56-040-942
CD40 Monoclonal Antibody (5C3), Alexa Fluor™ 700, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 56-040-942-Each-of-1 | In Stock | ₹ 30,288.24 |
56-040-942 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,288.24
GST (18%): ₹ 5,451.883
Total Price: ₹ 35,740.123
Antigen
CD40
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P25942
Gene Symbols
CD40
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
958
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
5C3
Conjugate
Alexa Fluor 700
Gene
CD40
Gene Alias
AI326936; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD antigen CD40; Cd40; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5); CD40 antigen, TNF receptor superfamily member 5; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDw40; GP39; HIGM1; I79_006806; IGM; IMD3; Immunoglobulin M; ImmunoglobulinM; membrane protein CD40; MGC9013; p50; receptor for ligand CD154; sCD40; soluble CD40; T-BAM; T-cell differentiation antigen; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The 5C3 monoclonal antibody reacts with human CD40, a 45-50 kDa type I transmembrane glycoprotein
- CD40 is a member of the TNFR family and is expressed by B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells
- CD40 regulates B cell development and maturation by inducing Ig isotype-switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation
- Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation
- 5C3 is reported to be used for activation of B cells in in vitro functional assays
- Applications Reported: This 5C3 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 5C3 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
- This may be used at 5 μL (0.25 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- The CD40 antigen is a single chain glycoprotein that is known to be a member of the tumor necrosis factor/nerve growth factor superfamily and shows a significant homology to the Hodgkin's disease associated antigen, CD30
- CD40 is present on all B cells except plasma cells and is also found on some epithelial cells, carcinomas and lymphoid dendritic cells
- CD40 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation
- AT-hook transcription factor AKNA is reported to coordinately regulate the expression of CD40, which may be important for homotypic cell interactions
- Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction
- The interaction of CD40 and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis
- Two alternatively spliced transcript variants of CD40 encoding distinct isoforms have been reported
- Diseases associated with CD40 dysfunction include Type 3 Hyper-Igm immunodeficiency and CD40 ligand deficiency.
Compare Similar Items
Show Difference
Antigen: CD40
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P25942
Gene Symbols: CD40
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 958
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 5C3
Conjugate: Alexa Fluor 700
Gene: CD40
Gene Alias: AI326936; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD antigen CD40; Cd40; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5); CD40 antigen, TNF receptor superfamily member 5; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDw40; GP39; HIGM1; I79_006806; IGM; IMD3; Immunoglobulin M; ImmunoglobulinM; membrane protein CD40; MGC9013; p50; receptor for ligand CD154; sCD40; soluble CD40; T-BAM; T-cell differentiation antigen; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD40
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P25942
Gene Symbols:
CD40
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
958
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
5C3
Conjugate:
Alexa Fluor 700
Gene:
CD40
Gene Alias:
AI326936; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD antigen CD40; Cd40; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5); CD40 antigen, TNF receptor superfamily member 5; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDw40; GP39; HIGM1; I79_006806; IGM; IMD3; Immunoglobulin M; ImmunoglobulinM; membrane protein CD40; MGC9013; p50; receptor for ligand CD154; sCD40; soluble CD40; T-BAM; T-cell differentiation antigen; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD45R (B220)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: P06800, P08575
Gene Symbols: PTPRC
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19264, 5788
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: RA3-6B2
Conjugate: Alexa Fluor 700
Gene: PTPRC
Gene Alias: B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD45R (B220)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
P06800, P08575
Gene Symbols:
PTPRC
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19264, 5788
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
RA3-6B2
Conjugate:
Alexa Fluor 700
Gene:
PTPRC
Gene Alias:
B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD45RA
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P08575
Gene Symbols: PTPRC
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5788
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: HI100
Conjugate: Alexa Fluor 700
Gene: PTPRC
Gene Alias: B220, CD45, CD45 antigen, CD45 antigen isoform 1 precursor, CD45 antigen isoform 2 precursor, CD45 antigen isoform 3 precursor, CD45 antigen isoform 4 precursor, CD45 antigen isoform 5 precursor, CD45 antigen isoform 6 precursor, CD45R, GP180, LCA, L-CA, leucocyte common antigen, Leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C, LY5, Ly-5, Lyt-4, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, protein tyrosine phosphatase, alternatively spliced, PTPRC, Receptor-type tyrosine-protein phosphatase C, RT7, T100, T200, T200 glycoprotein, T200 leukocyte common antigen
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD45RA
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P08575
Gene Symbols:
PTPRC
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5788
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
HI100
Conjugate:
Alexa Fluor 700
Gene:
PTPRC
Gene Alias:
B220, CD45, CD45 antigen, CD45 antigen isoform 1 precursor, CD45 antigen isoform 2 precursor, CD45 antigen isoform 3 precursor, CD45 antigen isoform 4 precursor, CD45 antigen isoform 5 precursor, CD45 antigen isoform 6 precursor, CD45R, GP180, LCA, L-CA, leucocyte common antigen, Leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C, LY5, Ly-5, Lyt-4, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, protein tyrosine phosphatase, alternatively spliced, PTPRC, Receptor-type tyrosine-protein phosphatase C, RT7, T100, T200, T200 glycoprotein, T200 leukocyte common antigen
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: CD47
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: Q08722
Gene Symbols: CD47
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 961
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: B6H12
Conjugate: Alexa Fluor 700
Gene: CD47
Gene Alias: 9130415E20Rik; AA407862; AI848868; antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; AW108519; B430305P08Rik; Cd47; CD47 antigen; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 antigen/integrin-associated protein; CD47 glycoprotein; CD47 molecule; CD47/IAP; IAP; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; Itgp; Leukocyte surface antigen CD47; MER6; OA3; Protein MER6; Rh-related antigen; sCD47; soluble CD 47; soluble CD47
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD47
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q08722
Gene Symbols:
CD47
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
961
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
B6H12
Conjugate:
Alexa Fluor 700
Gene:
CD47
Gene Alias:
9130415E20Rik; AA407862; AI848868; antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; AW108519; B430305P08Rik; Cd47; CD47 antigen; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 antigen/integrin-associated protein; CD47 glycoprotein; CD47 molecule; CD47/IAP; IAP; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; Itgp; Leukocyte surface antigen CD47; MER6; OA3; Protein MER6; Rh-related antigen; sCD47; soluble CD 47; soluble CD47
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ