56-206-182
CD206 (MMR) Monoclonal Antibody (MR6F3), Alexa Fluor™ 700, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 56-206-182-Each | In Stock | ₹ 25,210.25 |
56-206-182 - Each
In Stock
Quantity
1
Base Price: ₹ 25,210.25
GST (18%): ₹ 4,537.845
Total Price: ₹ 29,748.095
Antigen
CD206 (MMR)
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
Q61830
Gene Symbols
Mrc1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17533
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
MR6F3
Conjugate
Alexa Fluor 700
Gene
Mrc1
Gene Alias
AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- Rat Monoclonal Antibody CD206 (MSR, Mannose receptor, MRC1) is a 175 kDa transmembrane protein belonging to the group of pattern recognition receptors
- CD206 is predominantly expressed in tissue macrophages, dendritic cells, a subpopulation of endothelial cells and sperm cells
- CD206 is thought to play a role in the innate and adaptive immune response
- CD206 is also expressed on microglia and mato cells of the brain but not astrocytes or neurons
- CD206 also mediate the recognition and uptake of a variety of macromolecules, including modified lipoproteins, advanced glycation end (AGEs) products and amyloid b-protein (Abeta)
- While the normal role of CD206 is associated with cell adhesion and host defense mechanisms, it also has been implicated in the development of atherosclerosis and Amyloid beta deposition in Alzheimer's disease (AD)
- CD206’s gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing
- The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs)
- The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms
- CD206 has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis
- The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages
- Other diseases associated with CD206 dysfunction include leprosy and Gaucher’s Disease.
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Antigen: CD206 (MMR)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: Q61830
Gene Symbols: Mrc1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17533
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: MR6F3
Conjugate: Alexa Fluor 700
Gene: Mrc1
Gene Alias: AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD206 (MMR)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q61830
Gene Symbols:
Mrc1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17533
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
MR6F3
Conjugate:
Alexa Fluor 700
Gene:
Mrc1
Gene Alias:
AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: CD206 (MMR)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P22897
Gene Symbols: Mrc1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4360
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 19.2
Conjugate: Alexa Fluor 700
Gene: Mrc1
Gene Alias: AW259686, bA541I19.1, CD206, CELE_Y39A3CR.4, CLEC13D, CLEC13DL, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, ddp-1, hMR, Human mannose receptor, macrophage mannose receptor 1, Macrophage mannose receptor 1-like protein 1, mannose receptor, C type 1, mannose receptor, C type 1-like 1, Mitochondrial import inner membrane translocase subunit Tim8, MMR, MR, MRC1, MRC1L1, tim-8, Y39A3CR.4
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD206 (MMR)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P22897
Gene Symbols:
Mrc1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4360
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
19.2
Conjugate:
Alexa Fluor 700
Gene:
Mrc1
Gene Alias:
AW259686, bA541I19.1, CD206, CELE_Y39A3CR.4, CLEC13D, CLEC13DL, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, ddp-1, hMR, Human mannose receptor, macrophage mannose receptor 1, Macrophage mannose receptor 1-like protein 1, mannose receptor, C type 1, mannose receptor, C type 1-like 1, Mitochondrial import inner membrane translocase subunit Tim8, MMR, MR, MRC1, MRC1L1, tim-8, Y39A3CR.4
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: __
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Quantity: 10 mg
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10 mg
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Quantity: 50 mg
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50 mg
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