51-948-842

KLRG1 Monoclonal Antibody (13F12F2), Alexa Fluor™ 647, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 51-948-842-Each-of-1 In Stock ₹ 36,876.36

51-948-842 - Each of 1

₹ 36,876.36

In Stock

Quantity

1

Base Price: ₹ 36,876.36

GST (18%): ₹ 6,637.745

Total Price: ₹ 43,514.105

Antigen

KLRG1

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

Q96E93

Gene Symbols

Klrg1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10219

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

13F12F2

Conjugate

Alexa Fluor 647

Gene

Klrg1

Gene Alias

2F1; 2F1-Ag; CLEC15A; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin like receptor G1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; Klrg1; Mafa; MAFA-2F1; MAFAL; MAFA-L; MAFA-LIKE; MAFA-like receptor; Mast cell function-associated antigen; mast cell function-associated antigen (ITIM-containing); mast cell function-associated antigen 2F1; natural killer cell receptor

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • Description: This 13F12F2 monoclonal antibody reacts with human killer cell lectin-like receptor subfamily G, member 1 (KLRG1), a type II transmembrane inhibitor receptor of the C-type lectin superfamily that contains an ITIM domain
  • This inhibitory receptor is expressed on subsets of gamma-delta T cells, NK (CD56dim), CD8+ and CD4+ T Cells
  • KLRG1 is expressed primarily by cells with an effector/memory phenotype that are short-lived, but capable of immediate effector cell function
  • Cadherin-E, -N, and -R are ligands for KLRG1
  • Cadherin/KLRG1 interaction inhibits cytolytic activity and proliferation
  • The percentage of KLRG1 positive cells can vary considerably, depending on antigen experience
  • The clones 13F12F2 and 13A2 appear to recognize a similar epitope based on cross-blocking studies
  • Applications Reported: This 13F12F2 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 13F12F2 antibody has been pre-titrated and tested by flow cytometric analysis of human peripheral blood cells
  • This can be used at 5 μL (0.125 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains
  • These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1
  • KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells
  • NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.

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Invitrogen

51-948-842

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Antigen:
KLRG1

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q96E93

Gene Symbols:
Klrg1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10219

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
13F12F2

Conjugate:
Alexa Fluor 647

Gene:
Klrg1

Gene Alias:
2F1; 2F1-Ag; CLEC15A; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin like receptor G1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; Klrg1; Mafa; MAFA-2F1; MAFAL; MAFA-L; MAFA-LIKE; MAFA-like receptor; Mast cell function-associated antigen; mast cell function-associated antigen (ITIM-containing); mast cell function-associated antigen 2F1; natural killer cell receptor

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

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Antigen:
TIGIT

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q495A1

Gene Symbols:
TIGIT

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
201633

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MBSA43

Conjugate:
Alexa Fluor 647

Gene:
TIGIT

Gene Alias:
ENSMUSG00000071552; T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; TIGIT; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9; VSTM3; Washington University cell adhesion molecule; WUCAM

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Invitrogen

51-972-582

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Antigen:
COX2

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.:
P35354

Gene Symbols:
PTGS2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5743

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
COX 229

Conjugate:
Alexa Fluor 647

Gene:
PTGS2

Gene Alias:
COII, COX2, Cox-2, COXII, cyclooxygenase, cyclooxygenase 2, cyclooxygenase 2b, cyclooxygenase-2, Cytochrome c oxidase polypeptide II, Cytochrome c oxidase subunit 2, cytochrome c oxidase subunit II, glucocorticoid-regulated inflammatory cyclooxygenase, Gripghs, hCox-2, Macrophage activation-associated marker protein P71/73, mitochondrially encoded cytochrome c oxidase II, MTCO2, MT-CO2, PES-2, PGG/HS, PGH synthase 2, Pghs2, PGHS-2, Pghs-b, PHS II, PHS-2, prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, prostaglandin-endoperoxide synthase 2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), Ptgs2, Tis10, TIS10 protein

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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51-972-980

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Antigen:
Sall1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q9ER74

Gene Symbols:
SALL1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
58198

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
NRNSTNX

Conjugate:
Alexa Fluor 647

Gene:
SALL1

Gene Alias:
epididymis secretory protein Li 89; HEL-S-89; HSal1; Msal-3; SAL1; Sal-1; sal-3; SALL1; sal-like 1; sal-like 1 (Drosophila); sal-like protein 1; spalt like transcription factor 1; spalt-like transcription factor 1; TBS; Zinc finger protein 794; zinc finger protein SALL1; Zinc finger protein Spalt-1; zinc finger protein Spalt-3; ZNF794

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ