56-947-742

IDO Monoclonal Antibody (eyedio), Alexa Fluor™ 700, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 56-947-742-Each-of-1 In Stock ₹ 32,855.04

56-947-742 - Each of 1

₹ 32,855.04

In Stock

Quantity

1

Base Price: ₹ 32,855.04

GST (18%): ₹ 5,913.907

Total Price: ₹ 38,768.947

Antigen

IDO

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P14902

Gene Symbols

Ido1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3620

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

eyedio

Conjugate

Alexa Fluor 700

Gene

Ido1

Gene Alias

EC 1.13.11.52; IDO; IDO1; IDO-1; INDO; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; indoleamine-pyrrole 2,3-dioxygenase

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • This eyedio MAb reacts with human indoleamine-2, 3-dioxygenase (IDO, INDO, IDO1), an intracellular enzyme that catalyzes the degradation of tryptophan to kynurenines
  • IDO is expressed in a wide variety of tissues and cells, including macrophages, plasmacytoid dendritic cells, and several cell lines
  • IDO can be induced in many different cell types by IFN gamma or other inflammatory stimuli
  • Expression of IDO in antigen presenting cells and tumors is thought to mediate immune suppression through depletion of this essential amino acid and/or by the creation of tryptophan metabolites that cause apoptosis of T cells and induction of regulatory T cells
  • IDO1 is an intracellular heme-containing enzyme that catalyzes the oxidative cleavage of the indole ring of several important regulatory molecules like tryptophan, serotonin, and melatonin
  • By doing this, IDO1 initiates the production of biologically active metabolites, commonly referred to as kynurenines
  • IDO1 is widely expressed in a variety of human tissues as well as in macrophages and dendritic cells (DCs)
  • In inflammation, interferons (IFNs) act on specific receptors to trigger IDO1 induction
  • The production of IFN-gamma and induction of IDO1 represent important antimicrobial mechanisms
  • Degradation and depletion of tryptophan by IDO1 inhibits the growth of viruses, bacteria and parasites
  • Furthermore, IDO1 plays a complex and crucial role in immunoregulation during infection, pregnancy, autoimmunity, transplantation, and neoplasia.

Compare Similar Items

Show Difference

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Fischer Scientific

56-947-742

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Antigen:
IDO

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P14902

Gene Symbols:
Ido1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3620

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
eyedio

Conjugate:
Alexa Fluor 700

Gene:
Ido1

Gene Alias:
EC 1.13.11.52; IDO; IDO1; IDO-1; INDO; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; indoleamine-pyrrole 2,3-dioxygenase

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Invitrogen

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Antigen:
TIGIT

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q495A1

Gene Symbols:
TIGIT

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
201633

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MBSA43

Conjugate:
Alexa Fluor 700

Gene:
TIGIT

Gene Alias:
ENSMUSG00000071552; T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; TIGIT; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9; VSTM3; Washington University cell adhesion molecule; WUCAM

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Antigen:
Ly-6G

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.:
P35461

Gene Symbols:
Ly6g

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
546644

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
1A8-Ly6g

Conjugate:
Alexa Fluor 700

Gene:
Ly6g

Gene Alias:
Gr1, Gr-1, Ly6g, Ly-6G, ly-6G.1, lymphocyte antigen 6 complex, locus G, lymphocyte antigen 6G

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

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Antigen:
Alpha-Smooth Muscle Actin

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.5% BSA, 10% proprietary stabilizer and 0.05% sodium azide; pH 7.2

Gene Accession No.:
P62736

Gene Symbols:
__

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
59

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
1A4

Conjugate:
Alexa Fluor 700

Gene:
ACTA2

Gene Alias:
0610041G09Rik; AAT6; ACT-4; acta2; acta2.L; acta2.S; actin; Actin Alpha 2 Smooth Muscle Aorta; actin alpha 2, smooth muscle; Actin Vascular Smooth Muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha 2, smooth muscle, aorta L homeolog; actin, alpha 2, smooth muscle, aorta S homeolog; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; ACTSA; ACTVS; alpha actin 2; Alpha Cardiac Actin; alpha smooth muscle actin; alpha-actin; Alpha-actin-2; alpha-cardiac actin; alphaSMA; alpha-SM-actin; alpha-smooth muscle actin; Aortic Smooth Muscle; ASMA; a-sma; cell growth-inhibiting gene 46 protein; GIG46; Growth Inhibiting Gene 46; hypothetical protein LOC515610; LOW QUALITY PROTEIN: actin, aortic smooth muscle; mymy5; SM actin; sma; SMactin; sm-actin; SMalphaA; smooth muscle; smooth muscle alpha-actin; vascular smooth muscle alpha-actin; wu:fb63d03; XELAEV_18034370mg

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ