61-068-182

CD68 Monoclonal Antibody (FA-11), PE-eFluor™ 610, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 61-068-182-Each-of-1 In Stock ₹ 37,047.48

61-068-182 - Each of 1

₹ 37,047.48

In Stock

Quantity

1

Base Price: ₹ 37,047.48

GST (18%): ₹ 6,668.546

Total Price: ₹ 43,716.026

Antigen

CD68

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.

P31996

Gene Symbols

Cd68

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12514

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

FA-11

Conjugate

PE-eFluor 610

Gene

Cd68

Gene Alias

CD68, CD68 antigen, CD68 molecule, GP110, Lamp4, macrophage antigen CD68, macrosialin, Scard1, scavenger receptor class D, member 1, similar to CD68 antigen

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • Description: This FA-11 monoclonal antibody reacts with mouse CD68, known also as macrosialin
  • CD68 is a heavily O- and N- glycosylated type I integral membrane protein belonging to the sialomucin family and is closely related to the Lysosomal/endosomal-Associated Membrane Glycoproteins (LAMP)
  • Although commonly used as a pan-macrophage marker, low levels of expression have also been observed in Langerhans cells and conventional dendritic cells
  • CD68 is mostly localized in the late endosomes and lysosomes with a smaller fraction circulating to the cell surface
  • In the steady state, only about 10-15% of CD68 is present at the surface
  • Cell stimulation increases expression of CD68, its transport to cell surface, and results in glycoform remodeling
  • CD68 binds oxidized LDL and is involved in the process of phagocytosis
  • Applications Reported: This FA-11 antibody has been reported for use in intracellular staining followed by flow cytometric analysis
  • Applications Tested: This FA-11 antibody has been tested by intracellular staining followed by flow cytometric analysis of mouse bone marrow-derived macrophages using the Intracellular Fixation & Permeabilization Buffer Set (Product No
  • 88-8824-00) and protocol
  •  Please refer to Staining Intracellular Antigens for Flow Cytometry, Protocol A: Two step protocol for intracellular (cytoplasmic) proteins located under the Resources Tab online
  • This may be used at less than or equal to 1.0 μg per test
  • CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes
  • Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions
  • CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma
  • Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

Compare Similar Items

Show Difference

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Invitrogen

61-068-182

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Antigen:
CD68

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.:
P31996

Gene Symbols:
Cd68

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12514

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
FA-11

Conjugate:
PE-eFluor 610

Gene:
Cd68

Gene Alias:
CD68, CD68 antigen, CD68 molecule, GP110, Lamp4, macrophage antigen CD68, macrosialin, Scard1, scavenger receptor class D, member 1, similar to CD68 antigen

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Fischer Scientific

61-069-180

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Antigen:
CD69

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P37217

Gene Symbols:
CD69

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12515

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
H1.2F3

Conjugate:
PE-eFluor 610

Gene:
CD69

Gene Alias:
5830438K24Rik; Activation inducer molecule; activation inducer molecule (AIM/CD69); AI452015; AIM; BL-AC/P26; CD69; CD69 antigen; CD69 antigen (p60, early T-cell activation antigen); CD69 molecule; CLEC2C; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; EA1; early activation antigen CD69; early lymphocyte activation antigen; early T-cell activation antigen p60; GP32/28; leukocyte surface antigen Leu-23; MLR-3; VEA; Very Early Activation Antigen

Host Species:
Armenian Hamster

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

61-069-182

--


Antigen:
CD69

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P37217

Gene Symbols:
CD69

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12515

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
H1.2F3

Conjugate:
PE-eFluor 610

Gene:
CD69

Gene Alias:
5830438K24Rik; Activation inducer molecule; activation inducer molecule (AIM/CD69); AI452015; AIM; BL-AC/P26; CD69; CD69 antigen; CD69 antigen (p60, early T-cell activation antigen); CD69 molecule; CLEC2C; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; EA1; early activation antigen CD69; early lymphocyte activation antigen; early T-cell activation antigen p60; GP32/28; leukocyte surface antigen Leu-23; MLR-3; VEA; Very Early Activation Antigen

Host Species:
Armenian Hamster

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Invitrogen

61-069-942

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Antigen:
CD69

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
Q07108

Gene Symbols:
CD69

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
969

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
FN50

Conjugate:
PE-eFluor 610

Gene:
CD69

Gene Alias:
5830438K24Rik, Activation inducer molecule, activation inducer molecule (AIM/CD69), AI452015, AIM, BL-AC/P26, CD69, CD69 antigen, CD69 antigen (p60, early T-cell activation antigen), CD69 molecule, CLEC2C, C-type lectin domain family 2 member C, C-type lectin domain family 2, member C, EA1, early activation antigen CD69, early lymphocyte activation antigen, early T-cell activation antigen p60, GP32/28, leukocyte surface antigen Leu-23, MLR-3, VEA, Very Early Activation Antigen

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ