67-575-742
VSIG4 Monoclonal Antibody (JAV4), Super Bright™ 702, eBioscience™, Invitrogen™
Manufacturer: eBioscience
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 67-575-742-Each-of-1 | In Stock | ₹ 34,977.00 |
67-575-742 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,977.00
GST (18%): ₹ 6,295.86
Total Price: ₹ 41,272.86
Antigen
VSIG4
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
Q9Y279
Gene Symbols
VSIG4
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11326
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
JAV4
Conjugate
Super Bright 702
Gene
VSIG4
Gene Alias
A530061A11; BC025105; complement receptor of the immunoglobulin superfamily; CRIg; Ig superfamily protein; MGC137243 protein; protein Z39Ig; UNQ317/PRO362; V-set and immunoglobulin domain containing 4; V-set and immunoglobulin domain-containing protein 4; VSIG4; Z39IG
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: This JAV4 monoclonal antibody recognizes human V-Set and Immunoglobulin domain containing 4 (VSIG4), also known as Complement Receptor of the Immunoglobulin superfamily (CRIg) or Z39Ig
- There are two variants of human VSIG4 that result from alternative splicing
- Isoform 1 is longer and more prevalent than isoform 2, and this JAV4 antibody recognizes both
- VSIG4 is a type I transmembrane glycoprotein structurally related to the B7 family of immune regulatory proteins
- It contains one complete V-type Ig domain and one truncated C-type Ig domain
- VSIG4 is exclusively expressed on tissue resident and tumor infiltrating macrophages
- It has been shown to bind complement components C3b and iC3b
- This binding inhibits the alternative complement pathway and facilitates phagocytosis of complement-opsonized pathogens
- VSIG4 has also been reported to suppress T cell activation, proliferation and IL-2 production thereby playing a role in the maintece of peripheral T cell tolerance and suppression of established inflammation
- Expression of VSIG4 on tumor-infiltrating macrophages suggests its role in immune evasion
- Pro-inflammatory stimuli such as TNF and LPS have been reported to down-regulate the expression of VSIG4
- The JAV4 antibody will recognize VSIG4 on cells that have been formaldehyde-fixed and permeabilized
- This antibody does not cross-react with mouse or rat VSIG4
- Applications Reported: This JAV4 antibody has been reported for use in flow cytometric analysis
- T cell activation by APCs is positively and negatively regulated by members of the B7 family
- VSIG4 is a strong negative regulator of murine and human T cell proliferation and IL-2 production.
Compare Similar Items
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Antigen: VSIG4
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9Y279
Gene Symbols: VSIG4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11326
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: JAV4
Conjugate: Super Bright 702
Gene: VSIG4
Gene Alias: A530061A11; BC025105; complement receptor of the immunoglobulin superfamily; CRIg; Ig superfamily protein; MGC137243 protein; protein Z39Ig; UNQ317/PRO362; V-set and immunoglobulin domain containing 4; V-set and immunoglobulin domain-containing protein 4; VSIG4; Z39IG
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
VSIG4
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9Y279
Gene Symbols:
VSIG4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11326
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
JAV4
Conjugate:
Super Bright 702
Gene:
VSIG4
Gene Alias:
A530061A11; BC025105; complement receptor of the immunoglobulin superfamily; CRIg; Ig superfamily protein; MGC137243 protein; protein Z39Ig; UNQ317/PRO362; V-set and immunoglobulin domain containing 4; V-set and immunoglobulin domain-containing protein 4; VSIG4; Z39IG
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD366 (TIM3)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: Q8VIM0
Gene Symbols: Havcr2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 171285
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: RMT3-23
Conjugate: Super Bright 702
Gene: Havcr2
Gene Alias: CD366; FLJ14428; Havcr2; HAVcr-2; Hepatitis A virus cellular receptor 2; hepatitis A virus cellular receptor 2 homolog; kidney injury molecule-3; KIM-3; sCD366; soluble CD366; soluble TIM 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin family member 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; Tim3; TIM-3; TIMD3; TIMD-3
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD366 (TIM3)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q8VIM0
Gene Symbols:
Havcr2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
171285
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
RMT3-23
Conjugate:
Super Bright 702
Gene:
Havcr2
Gene Alias:
CD366; FLJ14428; Havcr2; HAVcr-2; Hepatitis A virus cellular receptor 2; hepatitis A virus cellular receptor 2 homolog; kidney injury molecule-3; KIM-3; sCD366; soluble CD366; soluble TIM 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin family member 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; Tim3; TIM-3; TIMD3; TIMD-3
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD357 (AITR/GITR)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: O35714
Gene Symbols: Tnfrsf18
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 21936
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: DTA-1
Conjugate: Super Bright 702
Gene: Tnfrsf18
Gene Alias: Activation-inducible TNFR family receptor; AITR; CD357; GITR; GITR-D; glucocorticoid-induced TNFR-related protein; PRO364; TNF receptor superfamily activation-inducible protein; TNF receptor superfamily member 18; TNFRSF18; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily, member 18; UNQ319; UNQ319/PRO364
Host Species: Rat
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD357 (AITR/GITR)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
O35714
Gene Symbols:
Tnfrsf18
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
21936
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
DTA-1
Conjugate:
Super Bright 702
Gene:
Tnfrsf18
Gene Alias:
Activation-inducible TNFR family receptor; AITR; CD357; GITR; GITR-D; glucocorticoid-induced TNFR-related protein; PRO364; TNF receptor superfamily activation-inducible protein; TNF receptor superfamily member 18; TNFRSF18; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily, member 18; UNQ319; UNQ319/PRO364
Host Species:
Rat
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: TER-119
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: 0
Gene Symbols: Ly76
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 104231
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: TER-119
Conjugate: Super Bright 702
Gene: Ly76
Gene Alias: Ly76; Ly-76; TER119
Host Species: Rat
Quantity: 25μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
TER-119
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
0
Gene Symbols:
Ly76
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
104231
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
TER-119
Conjugate:
Super Bright 702
Gene:
Ly76
Gene Alias:
Ly76; Ly-76; TER119
Host Species:
Rat
Quantity:
25μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ