70-168-4

ATG12 Recombinant Rabbit Monoclonal Antibody (20H24L24), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 70-168-4-Each-of-1 In Stock ₹ 49,368.12

70-168-4 - Each of 1

₹ 49,368.12

In Stock

Quantity

1

Base Price: ₹ 49,368.12

GST (18%): ₹ 8,886.262

Total Price: ₹ 58,254.382

Antigen

ATG12

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

O94817, Q2TBJ5, Q9CQY1

Gene Symbols

ATG12

Immunogen

Peptides corresponding to Human ATG12 (aa 43-57, 122-133).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Clone

20H24L24

Conjugate

Unconjugated

Gene

ATG12

Gene Alias

4931423H11Rik; A330058M13Rik; APG 12; APG12; Apg12 (autophagy, yeast) homolog; APG12L; APG12-like; ATG12; ATG12 autophagy related 12 homolog; Atg12l; Atg12p; Atg12-PB; Autophagy protein 12-like; autophagy related 12; autophagy related protein 12; autophagy-related 12; autophagy-related protein 12; Autophagy-specific gene 12; CG10861; CG10861-PB; Dmel\CG10861; Dmel_CG10861; FBR93; HAPG12; IP05205p; IP05405p; OTTHUMP00000159129; ubiquitin-like protein ATG12; YBR1506; YBR217W

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

361321, 67526, 9140

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with Frog, Pig and Rat
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • ATG12, a member of the autophagy protein family, forms a conjugate with ATG5; this conjugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy
  • This conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells
  • ATG12 has also been shown to interact with ATG10 in human embryonic kidney cells in the presence of ATG7
  • At least two isoforms of ATG12 are known to exist
  • Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells
  • It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components
  • This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1.

Compare Similar Items

Show Difference

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Thermo Scientific

70-168-4

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Antigen:
ATG12

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
O94817, Q2TBJ5, Q9CQY1

Gene Symbols:
ATG12

Immunogen:
Peptides corresponding to Human ATG12 (aa 43-57, 122-133).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
20H24L24

Conjugate:
Unconjugated

Gene:
ATG12

Gene Alias:
4931423H11Rik; A330058M13Rik; APG 12; APG12; Apg12 (autophagy, yeast) homolog; APG12L; APG12-like; ATG12; ATG12 autophagy related 12 homolog; Atg12l; Atg12p; Atg12-PB; Autophagy protein 12-like; autophagy related 12; autophagy related protein 12; autophagy-related 12; autophagy-related protein 12; Autophagy-specific gene 12; CG10861; CG10861-PB; Dmel\CG10861; Dmel_CG10861; FBR93; HAPG12; IP05205p; IP05405p; OTTHUMP00000159129; ubiquitin-like protein ATG12; YBR1506; YBR217W

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
361321, 67526, 9140

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

70-168-5

--


Antigen:
ATG16L1

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q676U5, Q8C0J2

Gene Symbols:
ATG16L1

Immunogen:
Full length protein corresponding to Human ATG16L1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
17H32L7

Conjugate:
Unconjugated

Gene:
ATG16L1

Gene Alias:
1500009K01Rik; A16L1; APG 16-L1; Apg16l; APG16L beta; APG16L isoforms 1; APG16-like 1; atg16; ATG16 autophagy related 16-like 1; ATG16A; Atg16l; Atg16l1; Atg16L1 gamma; autophagy related 16 like 1; autophagy related 16-like 1; autophagy related 16-like 1 (S. cerevisiae); autophagy-related 16-like 1; autophagy-related 16-like 1 gamma; autophagy-related protein 16-1; hCG_1817841; IBD10; UNQ9393/PRO34307; WD repeat domain 30; Wdr30

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
363278, 55054, 77040

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

70-169-6

--


Antigen:
BNIP3

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q12983

Gene Symbols:
BNIP3

Immunogen:
Protein corresponding to Human BNIP3 (aa 1-140)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
8H14L2

Conjugate:
Unconjugated

Gene:
BNIP3

Gene Alias:
BCL2 interacting protein 3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; BCL2/adenovirus E1B 19 kDa-interacting protein 1, NIP3; BCL2/adenovirus E1B 19 kDa-interacting protein 3; BCL2/adenovirus E1B 19kDa interacting protein 3; BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP3; BCL2/adenovirus E1B interacting protein 1, NIP3; BCL2/adenovirus E1B interacting protein 3; Bnip3; NIP3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
664

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

70-169-8

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Antigen:
FOXA2

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q9Y261

Gene Symbols:
FOXA2

Immunogen:
Protein corresponding to Human FOXA2 (aa 236-451)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, Immunocytochemistry, Western Blot

Clone:
9H5L7

Conjugate:
Unconjugated

Gene:
FOXA2

Gene Alias:
FKHL20; forkhead box A2; forkhead box protein A2; Foxa2; hepatic nuclear factor-3-beta; hepatocyte nuclear factor 3 beta (winged helix transcription factor); hepatocyte nuclear factor 3, beta; hepatocyte nuclear factor 3-beta; hepatocyte nuclear factor-3beta; HNF3B; Hnf-3b; HNF3beta; HNF-3BETA; HNF-3-beta; HNF3-beta; MGC19807; putative; RONU; TCF3B; TCF-3B; transcription factor; transcription factor 3B; transcription factor Foxa2; WHN

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3170

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid