70-243-3
ATG12-ATG5 Recombinant Rabbit Monoclonal Antibody (20H20L20), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 70-243-3-Each-of-1 | In Stock | ₹ 51,592.68 |
70-243-3 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,592.68
GST (18%): ₹ 9,286.682
Total Price: ₹ 60,879.362
Antigen
ATG12-ATG5
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
O94817, Q2TBJ5, Q3MQ06, Q99J83, Q9CQY1, Q9H1Y0
Gene Symbols
ATG12, ATG5
Immunogen
Peptides corresponding to Human ATG12 (aa 43-57, 122-133)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
20H20L20
Conjugate
Unconjugated
Gene
ATG12
Gene Alias
2010107M05Rik; 3110067M24Rik; 4931423H11Rik; A330058M13Rik; Apg12; Apg12 (autophagy, yeast) homolog; APG12L; APG12-like; APG5; Apg5l; APG5-LIKE; apoptosis-specific protein; ASP; Atg12; ATG12 autophagy related 12 homolog; Atg12l; Atg5; ATG5 autophagy related 5 homolog; Atg5l; Autophagy protein 5; autophagy related 12; autophagy related 5; autophagy-related 12; autophagy-related 5; autophagy-related protein 12; AW319544; C88337; FBR93; HAPG12; hAPG5; Paddy; Ubiquitin-like protein ATG12
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
11793, 361321, 365601, 67526, 9140, 9474
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody is predicted to react with Monkey, Pig, Cat and Mouse
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells
- It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components
- This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1
- ATG12, another member of the autophagy protein family, forms a conjugate with ATG5; this conjugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy
- This conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells
- ATG12 has also been shown to interact with ATG10 in human embryonic kidney cells in the presence of ATG7
- At least two isoforms of ATG12 are known to exist.
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Antigen: ATG12-ATG5
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O94817, Q2TBJ5, Q3MQ06, Q99J83, Q9CQY1, Q9H1Y0
Gene Symbols: ATG12, ATG5
Immunogen: Peptides corresponding to Human ATG12 (aa 43-57, 122-133)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 20H20L20
Conjugate: Unconjugated
Gene: ATG12
Gene Alias: 2010107M05Rik; 3110067M24Rik; 4931423H11Rik; A330058M13Rik; Apg12; Apg12 (autophagy, yeast) homolog; APG12L; APG12-like; APG5; Apg5l; APG5-LIKE; apoptosis-specific protein; ASP; Atg12; ATG12 autophagy related 12 homolog; Atg12l; Atg5; ATG5 autophagy related 5 homolog; Atg5l; Autophagy protein 5; autophagy related 12; autophagy related 5; autophagy-related 12; autophagy-related 5; autophagy-related protein 12; AW319544; C88337; FBR93; HAPG12; hAPG5; Paddy; Ubiquitin-like protein ATG12
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 11793, 361321, 365601, 67526, 9140, 9474
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
ATG12-ATG5
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O94817, Q2TBJ5, Q3MQ06, Q99J83, Q9CQY1, Q9H1Y0
Gene Symbols:
ATG12, ATG5
Immunogen:
Peptides corresponding to Human ATG12 (aa 43-57, 122-133)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
20H20L20
Conjugate:
Unconjugated
Gene:
ATG12
Gene Alias:
2010107M05Rik; 3110067M24Rik; 4931423H11Rik; A330058M13Rik; Apg12; Apg12 (autophagy, yeast) homolog; APG12L; APG12-like; APG5; Apg5l; APG5-LIKE; apoptosis-specific protein; ASP; Atg12; ATG12 autophagy related 12 homolog; Atg12l; Atg5; ATG5 autophagy related 5 homolog; Atg5l; Autophagy protein 5; autophagy related 12; autophagy related 5; autophagy-related 12; autophagy-related 5; autophagy-related protein 12; AW319544; C88337; FBR93; HAPG12; hAPG5; Paddy; Ubiquitin-like protein ATG12
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
11793, 361321, 365601, 67526, 9140, 9474
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: JAK2
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O60674
Gene Symbols: JAK2
Immunogen: Peptide corresponding to Human JAK2 (aa 1004-1012)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: 18H11L8
Conjugate: Unconjugated
Gene: JAK2
Gene Alias: EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3717
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
JAK2
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O60674
Gene Symbols:
JAK2
Immunogen:
Peptide corresponding to Human JAK2 (aa 1004-1012)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
18H11L8
Conjugate:
Unconjugated
Gene:
JAK2
Gene Alias:
EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3717
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: PIP5K1C
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: O60331
Gene Symbols: PIP5K1C
Immunogen: Peptides corresponding to human Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma [1) aa537-aa551 2) aa330-aa347]
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: 16H4L5
Conjugate: Unconjugated
Gene: PIP5K1C
Gene Alias: AI115456; AI835305; diphosphoinositide kinase; Kiaa0589; LCCS3; phosphatidylinositol 4-phosphate 5-kinase type I gamma; Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; phosphatidylinositol-4-phosphate 5-kinase; phosphatidylinositol-4-phosphate 5-kinase type 1 gamma; phosphatidylinositol-4-phosphate 5-kinase type I gamma; phosphatidylinositol-4-phosphate 5-kinase type-1 gamma; phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma; Pip5k1c; PIP5K1-gamma; PIP5Kgamma; PIP5K-GAMMA; PIP5KI gamma; Pip5kIgamma; PIP5KI-gamma; PIPKIg_v4; ptdIns(4)P-5-kinase 1 gamma; ptdIns(4)P-5-kinase gamma; ptdInsPKIgamma; type I PIP kinase
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23396
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
PIP5K1C
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
O60331
Gene Symbols:
PIP5K1C
Immunogen:
Peptides corresponding to human Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma [1) aa537-aa551 2) aa330-aa347]
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
16H4L5
Conjugate:
Unconjugated
Gene:
PIP5K1C
Gene Alias:
AI115456; AI835305; diphosphoinositide kinase; Kiaa0589; LCCS3; phosphatidylinositol 4-phosphate 5-kinase type I gamma; Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; phosphatidylinositol-4-phosphate 5-kinase; phosphatidylinositol-4-phosphate 5-kinase type 1 gamma; phosphatidylinositol-4-phosphate 5-kinase type I gamma; phosphatidylinositol-4-phosphate 5-kinase type-1 gamma; phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma; Pip5k1c; PIP5K1-gamma; PIP5Kgamma; PIP5K-GAMMA; PIP5KI gamma; Pip5kIgamma; PIP5KI-gamma; PIPKIg_v4; ptdIns(4)P-5-kinase 1 gamma; ptdIns(4)P-5-kinase gamma; ptdInsPKIgamma; type I PIP kinase
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23396
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: PFKFB2
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: O60825
Gene Symbols: Pfkfb2
Immunogen: Peptides corresponding to human PFKFB2 [1) aa490-aa505 2) aa6-aa22]
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 2H2L15
Conjugate: Unconjugated
Gene: Pfkfb2
Gene Alias: 4930568D07Rik; 6PF-2-K/Fru-2,6-P2ase 2; 6PF-2-K/Fru-2,6-P2ase heart-type isozyme; 6-phosphofructo-2-kinase; 6-phosphofructo-2-kinase /fructose-2,6-bisphosphatase; 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (heart); 6-phosphofructo-2-kinase/fructose2,6-bisphosphatase isoenzyme 2; fructose 6-P,2-kinase:fructose 2,6-bisphosphatase; fructose 6-phosphate 2-kinase/fructose 2,6-bisphosphatase; fructose 6-phosphate, 2-kinase:fructose 2,6-bisphosphatase; fructose 6-phosphate,2-kinase:fructose 2, 6-bisphosphatase; Fructose-2,6-bisphosphatase; fructose-2,6-bisphosphatase, cardiac isozyme; PFK/FBPase 2; PFK-2 car; PFK-2 cardiac; PFK-2/FBPase-2; PFK-2/FBPase-2 gene B; PFKFB, cardiac; PFKFB2; RH2K
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5208
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
PFKFB2
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
O60825
Gene Symbols:
Pfkfb2
Immunogen:
Peptides corresponding to human PFKFB2 [1) aa490-aa505 2) aa6-aa22]
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
2H2L15
Conjugate:
Unconjugated
Gene:
Pfkfb2
Gene Alias:
4930568D07Rik; 6PF-2-K/Fru-2,6-P2ase 2; 6PF-2-K/Fru-2,6-P2ase heart-type isozyme; 6-phosphofructo-2-kinase; 6-phosphofructo-2-kinase /fructose-2,6-bisphosphatase; 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (heart); 6-phosphofructo-2-kinase/fructose2,6-bisphosphatase isoenzyme 2; fructose 6-P,2-kinase:fructose 2,6-bisphosphatase; fructose 6-phosphate 2-kinase/fructose 2,6-bisphosphatase; fructose 6-phosphate, 2-kinase:fructose 2,6-bisphosphatase; fructose 6-phosphate,2-kinase:fructose 2, 6-bisphosphatase; Fructose-2,6-bisphosphatase; fructose-2,6-bisphosphatase, cardiac isozyme; PFK/FBPase 2; PFK-2 car; PFK-2 cardiac; PFK-2/FBPase-2; PFK-2/FBPase-2 gene B; PFKFB, cardiac; PFKFB2; RH2K
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5208
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid