70-278-8

Ataxin 3 Recombinant Rabbit Monoclonal Antibody (13H9L9), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 70-278-8-Each-of-1 In Stock ₹ 42,780.00

70-278-8 - Each of 1

₹ 42,780.00

In Stock

Quantity

1

Base Price: ₹ 42,780.00

GST (18%): ₹ 7,700.40

Total Price: ₹ 50,480.40

Antigen

Ataxin 3

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

P54252, Q9CVD2

Gene Symbols

ATXN3

Immunogen

Protein corresponding to human Ataxin 3 (aa1-aa364) (isoform 2)

Quantity

100μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

13H9L9

Conjugate

Unconjugated

Gene

ATXN3

Gene Alias

2210008M02Rik; AI463012; AI647473; AT3; ataxin 3; ataxin 3 variant an; ataxin 3 variant ao; ataxin 3 variant at; ataxin 3 variant e; ataxin 3 variant h; ataxin 3 variant m; ataxin 3 variant r; ataxin 3 variant ref; ataxin 3 variant y; ataxin3; ataxin-3; ATX3; ATXN3; JOS; josephin; Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3); Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3) homolog; Machado-Joseph disease protein 1; Machado-Joseph disease protein 1 homolog; MJD; MJD1; olivopontocerebellar ataxia 3; Rsca3; Sca3; spin; Spinocerebellar ataxia type 3 protein

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

110616, 4287

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with Monkey, Horse, Dog Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Machado-Joseph disease is an autosomal dominant neurologic disorder, and is now known to be the same as previously described spinocerebellar ataxia-3
  • MJD protein (Ataxin-3) contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is the cause of Machado-Joseph disease
  • There is a negative correlation between the age of onset and CAG repeat numbers
  • This protein interacts with key regulators (CBP, p300 and PCAF) of transcription and represses transcription, and also acts as a histone-binding protein that regulates transcription
  • MJD is a deubiquitinating enzyme.

Compare Similar Items

Show Difference

Img

Invitrogen

70-278-8

--


Antigen:
Ataxin 3

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
P54252, Q9CVD2

Gene Symbols:
ATXN3

Immunogen:
Protein corresponding to human Ataxin 3 (aa1-aa364) (isoform 2)

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
13H9L9

Conjugate:
Unconjugated

Gene:
ATXN3

Gene Alias:
2210008M02Rik; AI463012; AI647473; AT3; ataxin 3; ataxin 3 variant an; ataxin 3 variant ao; ataxin 3 variant at; ataxin 3 variant e; ataxin 3 variant h; ataxin 3 variant m; ataxin 3 variant r; ataxin 3 variant ref; ataxin 3 variant y; ataxin3; ataxin-3; ATX3; ATXN3; JOS; josephin; Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3); Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3) homolog; Machado-Joseph disease protein 1; Machado-Joseph disease protein 1 homolog; MJD; MJD1; olivopontocerebellar ataxia 3; Rsca3; Sca3; spin; Spinocerebellar ataxia type 3 protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
110616, 4287

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

70-278-9

--


Antigen:
DENND5A

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
G3V7Q0, Q6IQ26, Q6PAL8

Gene Symbols:
DENND5A

Immunogen:
Peptide corresponding to human DENND5A [aa828-aa847]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
14H6L8

Conjugate:
Unconjugated

Gene:
DENND5A

Gene Alias:
1500012B19Rik; AJ245569; AW496491; DENN domain containing 5A; DENN domain-containing protein 5A; DENN/MADD domain containing 5A; DENND5A; KIAA1091; mKIAA1091; ORF37; Rab6 interacting protein 1; rab6-interacting protein 1; RAB6IP1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
19347, 23258, 308942

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

70-279-2

--


Antigen:
TMEM230

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q96A57

Gene Symbols:
TMEM230

Immunogen:
Peptides corresponding to human TMEM230 [1) aa101-aa120 2) aa26-aa45]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
24H23L8

Conjugate:
Unconjugated

Gene:
TMEM230

Gene Alias:
5730494N06Rik; AA407821; C20orf30; dJ1116H23.2.1; HSPC274; HSPC274 protein; RGD1307399; TMEM230; Transmembrane protein 230; UNQ2432/PRO4992; UPF0414 transmembrane protein C20orf30; UPF0414 transmembrane protein C20orf30 homolog

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
29058

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

70-279-6

--


Antigen:
PTGES

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
O14684, Q9JM51

Gene Symbols:
PTGES

Immunogen:
Peptides corresponding to human PTGES [1) aa42-aa58 2) aa1-aa12]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
13H2L6

Conjugate:
Unconjugated

Gene:
PTGES

Gene Alias:
2410099E23Rik; D2Ertd369e; glutathione S-transferase 1-like 1; MGST1L1; MGST1-L1; MGST1-like 1; MGST-IV; Microsomal glutathione S-transferase 1-like 1; microsomal prostaglandin E synthase 1; microsomal prostaglandin E synthase-1; MPGES; MPGES1; mPGES-1; p53-induced apoptosis protein 12; p53-induced gene 12 protein; Pges; PIG12; PP102; PP1294; Prostaglandin E synthase; PTGES; TP53I12; tumor protein p53 inducible protein 12

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
64292, 9536

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid