70-335-6
TRADD Recombinant Rabbit Monoclonal Antibody (17H3L22), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 70-335-6-Each | In Stock | ₹ 39,841.01 |
70-335-6 - Each
In Stock
Quantity
1
Base Price: ₹ 39,841.01
GST (18%): ₹ 7,171.382
Total Price: ₹ 47,012.392
Antigen
TRADD
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.
Q15628
Gene Symbols
TRADD
Immunogen
Protein corresponding to human TRADD [aa1-aa312]
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
17H3L22
Conjugate
Unconjugated
Gene
TRADD
Gene Alias
9130005N23Rik; AA930854; Hs.89862; Hs89862; MGC11078; TNF receptor 1 associated signal transducer; TNFR1-associated DEATH domain protein; TNFRSF1A associated via death domain; TNFRSF1A-associated via death domain; TRADD; tumor necrosis factor receptor type 1 associated death domain protein; tumor necrosis factor receptor type 1-associated DEATH domain protein; tumor necrosis factor receptor-1-associated protein
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
8717
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody is predicted to react with Monkey, Bat, Cat
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- TRADD (Tumor necrosis factor receptor type 1-associated DEATH domain protein) is an important mediator of FAS and TNFR1 associated apoptotic signaling
- The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12
- TRADD acts by interacting with TRIP12 and leading to the disruption of the interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A
- TRADD acts as an adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interation with FADD
- Overexpression of TRADD leads to two major TNF-induced responses - apoptosis and activation of NF-kappa-B.
Compare Similar Items
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Antigen: TRADD
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: Q15628
Gene Symbols: TRADD
Immunogen: Protein corresponding to human TRADD [aa1-aa312]
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 17H3L22
Conjugate: Unconjugated
Gene: TRADD
Gene Alias: 9130005N23Rik; AA930854; Hs.89862; Hs89862; MGC11078; TNF receptor 1 associated signal transducer; TNFR1-associated DEATH domain protein; TNFRSF1A associated via death domain; TNFRSF1A-associated via death domain; TRADD; tumor necrosis factor receptor type 1 associated death domain protein; tumor necrosis factor receptor type 1-associated DEATH domain protein; tumor necrosis factor receptor-1-associated protein
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 8717
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TRADD
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
Q15628
Gene Symbols:
TRADD
Immunogen:
Protein corresponding to human TRADD [aa1-aa312]
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
17H3L22
Conjugate:
Unconjugated
Gene:
TRADD
Gene Alias:
9130005N23Rik; AA930854; Hs.89862; Hs89862; MGC11078; TNF receptor 1 associated signal transducer; TNFR1-associated DEATH domain protein; TNFRSF1A associated via death domain; TNFRSF1A-associated via death domain; TRADD; tumor necrosis factor receptor type 1 associated death domain protein; tumor necrosis factor receptor type 1-associated DEATH domain protein; tumor necrosis factor receptor-1-associated protein
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
8717
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: GABBR2
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: O75899, O88871
Gene Symbols: GABBR2
Immunogen: Peptide corresponding to human GABBR2 [ aa318-aa333]
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry
Clone: 19H3L12
Conjugate: Unconjugated
Gene: GABBR2
Gene Alias: FLJ36928; G protein-coupled receptor 51; GABA BR; GABA-B R2 receptor; GABA-B receptor 2; GABA-B receptor, R2 subunit; GABABR2; GABA-BR2; GABA-B-R2; Gabbr2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) B receptor 2; gamma-aminobutyric acid (GABA) B receptor, 2; gamma-aminobutyric acid B receptor 2; gamma-aminobutyric acid type B receptor subunit 2; gamma-aminobutyric acid type B receptor, subunit 2; gb2; Gm425; Gpr51; GPRC3B; G-protein coupled receptor 51; HG20; HRIHFB2099; MGC119386; MGC119388; MGC119389; ortholog of human G protein-coupled receptor 51 GPR51; RP23-337N2.1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 83633, 9568
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
GABBR2
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
O75899, O88871
Gene Symbols:
GABBR2
Immunogen:
Peptide corresponding to human GABBR2 [ aa318-aa333]
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry
Clone:
19H3L12
Conjugate:
Unconjugated
Gene:
GABBR2
Gene Alias:
FLJ36928; G protein-coupled receptor 51; GABA BR; GABA-B R2 receptor; GABA-B receptor 2; GABA-B receptor, R2 subunit; GABABR2; GABA-BR2; GABA-B-R2; Gabbr2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) B receptor 2; gamma-aminobutyric acid (GABA) B receptor, 2; gamma-aminobutyric acid B receptor 2; gamma-aminobutyric acid type B receptor subunit 2; gamma-aminobutyric acid type B receptor, subunit 2; gb2; Gm425; Gpr51; GPRC3B; G-protein coupled receptor 51; HG20; HRIHFB2099; MGC119386; MGC119388; MGC119389; ortholog of human G protein-coupled receptor 51 GPR51; RP23-337N2.1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
83633, 9568
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: H3.3 G34R oncohistone mutant
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: P84243
Gene Symbols: H3-3A, H3-3B
Immunogen: Peptides corresponding to human Histone H3.3 G34R/V [1)aa7-aa15 2)aa7-aa15]
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 4H1L8
Conjugate: Unconjugated
Gene: H3-3A
Gene Alias: H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3.3; H3.3 G34R; H3.3A; H3.3B; H3/g; H3-3A; H3-3B; H3B; H3F3; H3F3A; H3F3B; H3FT; H3t; Histone 3.3; Histone cluster 3; Histone H3; Histone H3.3; Histone H3.3 G34R; Histone H3.3G34R; PP781
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3020, 3021
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
H3.3 G34R oncohistone mutant
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
P84243
Gene Symbols:
H3-3A, H3-3B
Immunogen:
Peptides corresponding to human Histone H3.3 G34R/V [1)aa7-aa15 2)aa7-aa15]
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
4H1L8
Conjugate:
Unconjugated
Gene:
H3-3A
Gene Alias:
H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3.3; H3.3 G34R; H3.3A; H3.3B; H3/g; H3-3A; H3-3B; H3B; H3F3; H3F3A; H3F3B; H3FT; H3t; Histone 3.3; Histone cluster 3; Histone H3; Histone H3.3; Histone H3.3 G34R; Histone H3.3G34R; PP781
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3020, 3021
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: SIRT1
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: Q96EB6
Gene Symbols: SIRT1
Immunogen: Protein corresponding to human SIRT1 [aa608-aa747]
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ChIP Assay, Western Blot
Clone: 4H9L12
Conjugate: Unconjugated
Gene: SIRT1
Gene Alias: 75SirT1; AA673258; hSIR2; hSIRT1; mSIR2a; NAD-dependent deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; OTTHUMP00000198111; OTTHUMP00000198112; Regulatory protein SIR2 homolog 1; RP11-57G10.3; SIR2; Sir2a; SIR2alpha; SIR2L1; sir2-like 1; SIR2-like protein 1; SIRT 1; SIRT1; SIRT-1; SirtT1 75 kDa fragment; sirtuin 1; sirtuin 1 ((silent mating type information regulation 2, homolog) 1; sirtuin type 1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23411
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SIRT1
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
Q96EB6
Gene Symbols:
SIRT1
Immunogen:
Protein corresponding to human SIRT1 [aa608-aa747]
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP Assay, Western Blot
Clone:
4H9L12
Conjugate:
Unconjugated
Gene:
SIRT1
Gene Alias:
75SirT1; AA673258; hSIR2; hSIRT1; mSIR2a; NAD-dependent deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; OTTHUMP00000198111; OTTHUMP00000198112; Regulatory protein SIR2 homolog 1; RP11-57G10.3; SIR2; Sir2a; SIR2alpha; SIR2L1; sir2-like 1; SIR2-like protein 1; SIRT 1; SIRT1; SIRT-1; SirtT1 75 kDa fragment; sirtuin 1; sirtuin 1 ((silent mating type information regulation 2, homolog) 1; sirtuin type 1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23411
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid