70-336-8
SIRT1 Recombinant Rabbit Monoclonal Antibody (4H9L12), Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 70-336-8-Each-of-1 | In Stock | ₹ 42,780.00 |
70-336-8 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,780.00
GST (18%): ₹ 7,700.40
Total Price: ₹ 50,480.40
Antigen
SIRT1
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.
Q96EB6
Gene Symbols
SIRT1
Immunogen
Protein corresponding to human SIRT1 [aa608-aa747]
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ChIP Assay, Western Blot
Clone
4H9L12
Conjugate
Unconjugated
Gene
SIRT1
Gene Alias
75SirT1; AA673258; hSIR2; hSIRT1; mSIR2a; NAD-dependent deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; OTTHUMP00000198111; OTTHUMP00000198112; Regulatory protein SIR2 homolog 1; RP11-57G10.3; SIR2; Sir2a; SIR2alpha; SIR2L1; sir2-like 1; SIR2-like protein 1; SIRT 1; SIRT1; SIRT-1; SirtT1 75 kDa fragment; sirtuin 1; sirtuin 1 ((silent mating type information regulation 2, homolog) 1; sirtuin type 1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
23411
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody is predicted to react with Monkey, Pig, Cat
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- NAD-dependent protein deacetylase sirtuin-1 (SIRT1) links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, repsonse to DNA damage, metabolism, apoptosis, and autophagy
- SIRT1 can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histone and DNA, leading to transcriptional repression
- It is essential in skeletal muscle cell differentiation and in response to low nutrients mediates the inhibitory effect on skeletal myoblast differentiation which also involves 5'-AMP-activated protein kinase (AMPK) and nicotinamide phosphoribosyltransferase (NAMPT).
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Antigen: SIRT1
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: Q96EB6
Gene Symbols: SIRT1
Immunogen: Protein corresponding to human SIRT1 [aa608-aa747]
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ChIP Assay, Western Blot
Clone: 4H9L12
Conjugate: Unconjugated
Gene: SIRT1
Gene Alias: 75SirT1; AA673258; hSIR2; hSIRT1; mSIR2a; NAD-dependent deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; OTTHUMP00000198111; OTTHUMP00000198112; Regulatory protein SIR2 homolog 1; RP11-57G10.3; SIR2; Sir2a; SIR2alpha; SIR2L1; sir2-like 1; SIR2-like protein 1; SIRT 1; SIRT1; SIRT-1; SirtT1 75 kDa fragment; sirtuin 1; sirtuin 1 ((silent mating type information regulation 2, homolog) 1; sirtuin type 1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23411
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SIRT1
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
Q96EB6
Gene Symbols:
SIRT1
Immunogen:
Protein corresponding to human SIRT1 [aa608-aa747]
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP Assay, Western Blot
Clone:
4H9L12
Conjugate:
Unconjugated
Gene:
SIRT1
Gene Alias:
75SirT1; AA673258; hSIR2; hSIRT1; mSIR2a; NAD-dependent deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; OTTHUMP00000198111; OTTHUMP00000198112; Regulatory protein SIR2 homolog 1; RP11-57G10.3; SIR2; Sir2a; SIR2alpha; SIR2L1; sir2-like 1; SIR2-like protein 1; SIRT 1; SIRT1; SIRT-1; SirtT1 75 kDa fragment; sirtuin 1; sirtuin 1 ((silent mating type information regulation 2, homolog) 1; sirtuin type 1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23411
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: MBD1
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.4
Gene Accession No.: Q9UIS9
Gene Symbols: MBD1
Immunogen: Protein corresponding to human MBD1 [aa400-aa605]
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot, Western Blot
Clone: 12H8L4
Conjugate: Unconjugated
Gene: MBD1
Gene Alias: CXXC3, CXXC-type zinc finger protein 3, Mbd1, methyl-CpG binding domain protein 1, methyl-CpG binding domain protein 1 isoform PCM1, methyl-CpG-binding domain protein 1, Methyl-CpG-binding protein MBD1, PCM1, Protein containing methyl-CpG-binding domain 1, RFT, the regulator of fibroblast growth factor 2 (FGF-2) transcription
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4152
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MBD1
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.4
Gene Accession No.:
Q9UIS9
Gene Symbols:
MBD1
Immunogen:
Protein corresponding to human MBD1 [aa400-aa605]
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot, Western Blot
Clone:
12H8L4
Conjugate:
Unconjugated
Gene:
MBD1
Gene Alias:
CXXC3, CXXC-type zinc finger protein 3, Mbd1, methyl-CpG binding domain protein 1, methyl-CpG binding domain protein 1 isoform PCM1, methyl-CpG-binding domain protein 1, Methyl-CpG-binding protein MBD1, PCM1, Protein containing methyl-CpG-binding domain 1, RFT, the regulator of fibroblast growth factor 2 (FGF-2) transcription
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4152
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Apolipoprotein J
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: P10909
Gene Symbols: Clu
Immunogen: Peptides corresponding to human Apolipoprotein J [1) aa141 - aa160 2) aa426-aa445]
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: 12H12L20
Conjugate: Unconjugated
Gene: Clu
Gene Alias: AAG4; Aging associated protein 4; Aging-associated gene 4 protein; aging-associated protein 4; AI893575; apo j; Apo J a; Apo J alpha; Apo J b; Apo J beta; Apo J a; Apo J β; Apo Ja; Apo Jb; ApoJ; Apo-J; ApoJ a; ApoJ alpha; ApoJ b; ApoJ beta; ApoJ a; ApoJ β; ApoJa; ApoJalpha; ApoJb; ApoJbeta; Apolipoprotein J; CLI; Clu; CLU1; CLU2; clusterin; Clusterin alpha / beta chain; Clusterin alpha chain; Clusterin beta chain; Clustrin; Complement associated protein SP40; complement cytolysis inhibitor; Complement cytolysis inhibitor a chain; Complement cytolysis inhibitor b chain; complement lysis inhibitor; complement-associated protein SP-40,40; D14Ucla3; DAG; Dimeric acid glycoprotein; GP80; HGNC:2095; ku70-binding protein 1; Ku70-binding protein 1 (KUB1); KUB1; MGC24903; Msgp-2; NA1/NA2; RATTRPM2B; SGP2; Sgp-2; SP40; SP-40; Sugp-2; sulfated glycoprotein 2; Sulfated glycoprotein 2 (SGP2); testosterone repressed prostate message; testosterone repressed prostate message 2; Testosterone
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1191
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Apolipoprotein J
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
P10909
Gene Symbols:
Clu
Immunogen:
Peptides corresponding to human Apolipoprotein J [1) aa141 - aa160 2) aa426-aa445]
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
12H12L20
Conjugate:
Unconjugated
Gene:
Clu
Gene Alias:
AAG4; Aging associated protein 4; Aging-associated gene 4 protein; aging-associated protein 4; AI893575; apo j; Apo J a; Apo J alpha; Apo J b; Apo J beta; Apo J a; Apo J β; Apo Ja; Apo Jb; ApoJ; Apo-J; ApoJ a; ApoJ alpha; ApoJ b; ApoJ beta; ApoJ a; ApoJ β; ApoJa; ApoJalpha; ApoJb; ApoJbeta; Apolipoprotein J; CLI; Clu; CLU1; CLU2; clusterin; Clusterin alpha / beta chain; Clusterin alpha chain; Clusterin beta chain; Clustrin; Complement associated protein SP40; complement cytolysis inhibitor; Complement cytolysis inhibitor a chain; Complement cytolysis inhibitor b chain; complement lysis inhibitor; complement-associated protein SP-40,40; D14Ucla3; DAG; Dimeric acid glycoprotein; GP80; HGNC:2095; ku70-binding protein 1; Ku70-binding protein 1 (KUB1); KUB1; MGC24903; Msgp-2; NA1/NA2; RATTRPM2B; SGP2; Sgp-2; SP40; SP-40; Sugp-2; sulfated glycoprotein 2; Sulfated glycoprotein 2 (SGP2); testosterone repressed prostate message; testosterone repressed prostate message 2; Testosterone
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1191
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: JMJD2C
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.4
Gene Accession No.: Q9H3R0
Gene Symbols: KDM4C
Immunogen: Peptides corresponding to human KDM4C [1) aa1019-aa1038 2) aa494-aa513]
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 23H4L4
Conjugate: Unconjugated
Gene: KDM4C
Gene Alias: 2410141F18Rik, AA517467, bA146B14.1, GASC1, GASC-1 protein, gene amplified in squamous cell carcinoma 1, gene amplified in squamous cell carcinoma 1 protein, JHDM3C, JmjC domain-containing histone demethylation protein 3C, JMJD2C, jumonji domain containing 2C, jumonji domain-containing protein 2C, Kdm4c, KIAA0780, lysine (K)-specific demethylase 4C, lysine demethylase 4C, lysine-specific demethylase 4C, RP11-169L18.1, TDRD14C, tudor domain containing 14C
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23081
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
JMJD2C
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.4
Gene Accession No.:
Q9H3R0
Gene Symbols:
KDM4C
Immunogen:
Peptides corresponding to human KDM4C [1) aa1019-aa1038 2) aa494-aa513]
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
23H4L4
Conjugate:
Unconjugated
Gene:
KDM4C
Gene Alias:
2410141F18Rik, AA517467, bA146B14.1, GASC1, GASC-1 protein, gene amplified in squamous cell carcinoma 1, gene amplified in squamous cell carcinoma 1 protein, JHDM3C, JmjC domain-containing histone demethylation protein 3C, JMJD2C, jumonji domain containing 2C, jumonji domain-containing protein 2C, Kdm4c, KIAA0780, lysine (K)-specific demethylase 4C, lysine demethylase 4C, lysine-specific demethylase 4C, RP11-169L18.1, TDRD14C, tudor domain containing 14C
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23081
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid