70-365-3

SIRT1 Recombinant Rabbit Monoclonal Antibody (2H9L18), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 70-365-3-Each-of-1 In Stock ₹ 42,780.00

70-365-3 - Each of 1

₹ 42,780.00

In Stock

Quantity

1

Base Price: ₹ 42,780.00

GST (18%): ₹ 7,700.40

Total Price: ₹ 50,480.40

Antigen

SIRT1

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

Q96EB6

Gene Symbols

SIRT1

Immunogen

Protein corresponding to human SIRT1 [aa608-aa747]

Quantity

100μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

ChIP Assay, Immunocytochemistry

Clone

2H9L18

Conjugate

Unconjugated

Gene

SIRT1

Gene Alias

75SirT1; AA673258; hSIR2; hSIRT1; mSIR2a; NAD-dependent deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; OTTHUMP00000198111; OTTHUMP00000198112; Regulatory protein SIR2 homolog 1; RP11-57G10.3; SIR2; Sir2a; SIR2alpha; SIR2L1; sir2-like 1; SIR2-like protein 1; SIRT 1; SIRT1; SIRT-1; SirtT1 75 kDa fragment; sirtuin 1; sirtuin 1 ((silent mating type information regulation 2, homolog) 1; sirtuin type 1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

23411

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with Monkey, Pig, Cat
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • NAD-dependent protein deacetylase sirtuin-1 (SIRT1) links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, repsonse to DNA damage, metabolism, apoptosis, and autophagy
  • SIRT1 can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histone and DNA, leading to transcriptional repression
  • It is essential in skeletal muscle cell differentiation and in response to low nutrients mediates the inhibitory effect on skeletal myoblast differentiation which also involves 5'-AMP-activated protein kinase (AMPK) and nicotinamide phosphoribosyltransferase (NAMPT).

Compare Similar Items

Show Difference

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Invitrogen

70-365-3

--


Antigen:
SIRT1

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q96EB6

Gene Symbols:
SIRT1

Immunogen:
Protein corresponding to human SIRT1 [aa608-aa747]

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, Immunocytochemistry

Clone:
2H9L18

Conjugate:
Unconjugated

Gene:
SIRT1

Gene Alias:
75SirT1; AA673258; hSIR2; hSIRT1; mSIR2a; NAD-dependent deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; OTTHUMP00000198111; OTTHUMP00000198112; Regulatory protein SIR2 homolog 1; RP11-57G10.3; SIR2; Sir2a; SIR2alpha; SIR2L1; sir2-like 1; SIR2-like protein 1; SIRT 1; SIRT1; SIRT-1; SirtT1 75 kDa fragment; sirtuin 1; sirtuin 1 ((silent mating type information regulation 2, homolog) 1; sirtuin type 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23411

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

70-365-8

--


Antigen:
GPIP137

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q14444

Gene Symbols:
Caprin1

Immunogen:
Protein corresponding to human GPIP137 [aa132-aa251]

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunoprecipitation

Clone:
6H17L10

Conjugate:
Unconjugated

Gene:
Caprin1

Gene Alias:
activation/proliferation-associated protein 1; AL022980; caprin 1; Caprin1; caprin-1; cell cycle associated protein 1; cell cycle-associated protein 1; cytop; Cytoplasmic activation- and proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein-1; G5E5; GPI p137; GPI-anchored membrane protein 1; GPI-anchored protein p137; Gpiap; GPIAP1; Gpip137; GPI-p137; GRIP137; M11S1; Membrane component chromosome 11 surface marker 1; membrane component, chromosome 11, surface marker 1; Mmgpip137; P137; p137GPI; RNA granule protein 105; Rng105

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4076

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

70-366-2

--


Antigen:
H3.3 G34V oncohistone mutant

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.4

Gene Accession No.:
P84243

Gene Symbols:
H3-3A, H3-3B

Immunogen:
Peptides corresponding to human H3.3 G34V [1) STGVVKKPH 2) STGRVKKPH]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, Western Blot

Clone:
1H32L36

Conjugate:
Unconjugated

Gene:
H3-3A

Gene Alias:
H3 histone, family 3A, H3 histone, family 3B, H3 histone, family 3B (H3.3B), H3.3, H3.3 G34V, H3.3A, H3.3B, H3/g, H3-3A, H3-3B, H3B, H3F3, H3F3A, H3F3B, H3FT, H3t, Histone 3.3, Histone cluster 3, Histone H3, Histone H3.3, Histone H3.3 G34V, Histone H3.3G34V, PP781

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3020, 3021

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

70-367-3

--


Antigen:
CSK

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.4

Gene Accession No.:
P41240

Gene Symbols:
CSK

Immunogen:
Protein corresponding to human CSK [aa73-aa178]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
5H3L21

Conjugate:
Unconjugated

Gene:
CSK

Gene Alias:
AW212630, CSK, CSK, non-receptor tyrosine kinase, C-SRC kinase, c-src tyrosine kinase, C-terminal Src kinase, MGC117393, p50CSK, protein-tyrosine kinase (CSK), protein-tyrosine kinase CYL, Protein-tyrosine kinase MPK-2, Tyrosine-protein kinase CSK

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1445

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid