70-337-3

Apolipoprotein J Recombinant Rabbit Monoclonal Antibody (12H12L20), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 70-337-3-Each-of-1 In Stock ₹ 48,769.20

70-337-3 - Each of 1

₹ 48,769.20

In Stock

Quantity

1

Base Price: ₹ 48,769.20

GST (18%): ₹ 8,778.456

Total Price: ₹ 57,547.656

Antigen

Apolipoprotein J

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

P10909

Gene Symbols

Clu

Immunogen

Peptides corresponding to human Apolipoprotein J [1) aa141 - aa160 2) aa426-aa445]

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Clone

12H12L20

Conjugate

Unconjugated

Gene

Clu

Gene Alias

AAG4; Aging associated protein 4; Aging-associated gene 4 protein; aging-associated protein 4; AI893575; apo j; Apo J a; Apo J alpha; Apo J b; Apo J beta; Apo J a; Apo J β; Apo Ja; Apo Jb; ApoJ; Apo-J; ApoJ a; ApoJ alpha; ApoJ b; ApoJ beta; ApoJ a; ApoJ β; ApoJa; ApoJalpha; ApoJb; ApoJbeta; Apolipoprotein J; CLI; Clu; CLU1; CLU2; clusterin; Clusterin alpha / beta chain; Clusterin alpha chain; Clusterin beta chain; Clustrin; Complement associated protein SP40; complement cytolysis inhibitor; Complement cytolysis inhibitor a chain; Complement cytolysis inhibitor b chain; complement lysis inhibitor; complement-associated protein SP-40,40; D14Ucla3; DAG; Dimeric acid glycoprotein; GP80; HGNC:2095; ku70-binding protein 1; Ku70-binding protein 1 (KUB1); KUB1; MGC24903; Msgp-2; NA1/NA2; RATTRPM2B; SGP2; Sgp-2; SP40; SP-40; Sugp-2; sulfated glycoprotein 2; Sulfated glycoprotein 2 (SGP2); testosterone repressed prostate message; testosterone repressed prostate message 2; Testosterone

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1191

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with Mouse, Rat, Bovine
  • Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins
  • Prevents stress-induced aggregation of blood plasma proteins
  • Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro)
  • Does not require ATP
  • Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70
  • Does not refold proteins by itself
  • Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysosomal or proteasomal degradation
  • Secreted isoform 1 protects cells against apoptosis and against cytolysis by complement
  • Intracellular isoforms interact with ubiquitin and SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes and promote the ubiquitination and subsequent proteasomal degradation of target proteins
  • Promotes proteasomal degradation of COMMD1 and IKBKB
  • Modulates NF-kappa-B transcriptional activity
  • Nuclear isoforms promote apoptosis
  • Mitochondrial isoforms suppress BAX-dependent release of cytochrome c into the cytoplasm and inhibit apoptosis
  • Plays a role in the regulation of cell proliferation.

Compare Similar Items

Show Difference

Img

Invitrogen

70-337-3

--


Antigen:
Apolipoprotein J

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
P10909

Gene Symbols:
Clu

Immunogen:
Peptides corresponding to human Apolipoprotein J [1) aa141 - aa160 2) aa426-aa445]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
12H12L20

Conjugate:
Unconjugated

Gene:
Clu

Gene Alias:
AAG4; Aging associated protein 4; Aging-associated gene 4 protein; aging-associated protein 4; AI893575; apo j; Apo J a; Apo J alpha; Apo J b; Apo J beta; Apo J a; Apo J β; Apo Ja; Apo Jb; ApoJ; Apo-J; ApoJ a; ApoJ alpha; ApoJ b; ApoJ beta; ApoJ a; ApoJ β; ApoJa; ApoJalpha; ApoJb; ApoJbeta; Apolipoprotein J; CLI; Clu; CLU1; CLU2; clusterin; Clusterin alpha / beta chain; Clusterin alpha chain; Clusterin beta chain; Clustrin; Complement associated protein SP40; complement cytolysis inhibitor; Complement cytolysis inhibitor a chain; Complement cytolysis inhibitor b chain; complement lysis inhibitor; complement-associated protein SP-40,40; D14Ucla3; DAG; Dimeric acid glycoprotein; GP80; HGNC:2095; ku70-binding protein 1; Ku70-binding protein 1 (KUB1); KUB1; MGC24903; Msgp-2; NA1/NA2; RATTRPM2B; SGP2; Sgp-2; SP40; SP-40; Sugp-2; sulfated glycoprotein 2; Sulfated glycoprotein 2 (SGP2); testosterone repressed prostate message; testosterone repressed prostate message 2; Testosterone

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1191

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

70-338-0

--


Antigen:
JMJD2C

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.4

Gene Accession No.:
Q9H3R0

Gene Symbols:
KDM4C

Immunogen:
Peptides corresponding to human KDM4C [1) aa1019-aa1038 2) aa494-aa513]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
23H4L4

Conjugate:
Unconjugated

Gene:
KDM4C

Gene Alias:
2410141F18Rik, AA517467, bA146B14.1, GASC1, GASC-1 protein, gene amplified in squamous cell carcinoma 1, gene amplified in squamous cell carcinoma 1 protein, JHDM3C, JmjC domain-containing histone demethylation protein 3C, JMJD2C, jumonji domain containing 2C, jumonji domain-containing protein 2C, Kdm4c, KIAA0780, lysine (K)-specific demethylase 4C, lysine demethylase 4C, lysine-specific demethylase 4C, RP11-169L18.1, TDRD14C, tudor domain containing 14C

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23081

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

70-338-2

--


Antigen:
PKM2

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
P14618

Gene Symbols:
PKM

Immunogen:
Peptides corresponding to human PKM2 [(aa476-aa493) (aa120-aa136)]

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
3H4L19

Conjugate:
Unconjugated

Gene:
PKM

Gene Alias:
AA414905; AL024370; AL024424; ATP:pyruvate 2-o-phosphotransferase; CTHBP; Cytosolic thyroid hormone-binding protein; epididymis secretory protein Li 30; HEL-S-30; isozymes M1/M2; m2pk; muscle pyruvate kinase; OIP3; OIP-3; OPA-interacting protein 3; p58; PK, muscle type; PK2; Pk-2; Pk3; Pk-3; PKLR; PKM; pkm.L; PKM12; PKM2; Pykm; pyruvate kinase; pyruvate kinase 2/3; pyruvate kinase 3; pyruvate kinase isozymes M1/M2; pyruvate kinase M1/2; pyruvate kinase M1/2 L homeolog; pyruvate kinase M1/2 L homeolog; pyruvate kinase, muscle; pyruvate kinase muscle isozyme; Pyruvate kinase PKM; pyruvate kinase, liver and RBC; pyruvate kinase, muscle; TCB; THBP1; thyroid hormone-binding protein 1; thyroid hormone-binding protein, cytosolic; tu; tumor M2-PK; XELAEV_18018020mg

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5315

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

70-338-3

--


Antigen:
P2Y6

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q15077

Gene Symbols:
P2ry6

Immunogen:
Peptides corresponding to human P2Y6 [1) aa132-aa144 2) aa256-aa272]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
8H45L52

Conjugate:
Unconjugated

Gene:
P2ry6

Gene Alias:
2010204J23Rik; G-coupled nucleotide receptor; MGC15335; P2 purinoceptor; P2ry6; P2Y ATP receptor 6; P2Y purinoceptor 6; p2y3 and chick; p2y3 receptor; P2Y6; P2Y6 receptor; PP2891; Purinoceptor p2y6; pyrimidinergic receptor P2Y, G-protein coupled, 6; pyrimidinergic receptor P2Y6

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5031

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid