70-380-9

TP63 Recombinant Rabbit Monoclonal Antibody (10H7L17), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 70-380-9-Each-of-1 In Stock ₹ 42,780.00

70-380-9 - Each of 1

₹ 42,780.00

In Stock

Quantity

1

Base Price: ₹ 42,780.00

GST (18%): ₹ 7,700.40

Total Price: ₹ 50,480.40

Antigen

TP63

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide, pH 7.4

Gene Accession No.

Q9H3D4

Gene Symbols

TP63

Immunogen

Protein corresponding to human TP63 [aa360-aa500]

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot, Western Blot

Clone

10H7L17

Conjugate

Unconjugated

Gene

TP63

Gene Alias

AIS, amplified in squamous cell carcinoma, B(p51A), B(p51B), Chronic μgcerative stomatitis protein, CUSP, EEC3, Keratinocyte transcription factor KET, KET, LMS, NBP, OFC8, p40, p51, p53CP, p63, p63a, P73H, p73L, RHS, SHFM4, TP53CP, TP53L, TP63, TP73L, Transformation-related protein 63, tumor protein 63, tumor protein p53-competing protein, tumor protein p63, Tumor protein p73-like

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

8626

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with Monkey, Mouse, Rat, Bovine
  • TP63 (tumor protein 63) acts as a sequence-specific DNA binding transcriptional activator or repressor
  • The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform-specific activity
  • Isoform 2 activates RIPK4 transcription
  • TP63 may be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes
  • It is involved in Notch signaling by inducing JAG1 and JAG2
  • TP63 plays a role in the regulation of epithelial morphogenesis
  • The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm
  • TP63 is required for limb formation from the apical ectodermal ridge
  • It also activates transcription of the p21 promoter
  • Mutations affecting the gene can result in Acro-dermato-ungual-lacrimal-tooth syndrome, ankyloblepharon-ectodermal defects-cleft lip/palate, ectrodactyly ectodermal dysplasia, split-hand/foot malformation 4, limb-mammary syndrome, ectodermal dysplasia - Rapp-Hodgkin type, and orofacial cleft 8.

Compare Similar Items

Show Difference

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Invitrogen

70-380-9

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Antigen:
TP63

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.4

Gene Accession No.:
Q9H3D4

Gene Symbols:
TP63

Immunogen:
Protein corresponding to human TP63 [aa360-aa500]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot, Western Blot

Clone:
10H7L17

Conjugate:
Unconjugated

Gene:
TP63

Gene Alias:
AIS, amplified in squamous cell carcinoma, B(p51A), B(p51B), Chronic μgcerative stomatitis protein, CUSP, EEC3, Keratinocyte transcription factor KET, KET, LMS, NBP, OFC8, p40, p51, p53CP, p63, p63a, P73H, p73L, RHS, SHFM4, TP53CP, TP53L, TP63, TP73L, Transformation-related protein 63, tumor protein 63, tumor protein p53-competing protein, tumor protein p63, Tumor protein p73-like

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8626

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Fischer Scientific

70-381-0

--


Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
10 mg

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Img

Invitrogen

70-381-1

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Antigen:
CALCRL

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q16602, Q63118

Gene Symbols:
CALCRL

Immunogen:
Peptides corresponding to human CALCRL [1) aa23-aa40 2) aa48-aa64]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Clone:
8H9L8

Conjugate:
Unconjugated

Gene:
CALCRL

Gene Alias:
AV071593; Calcitonin gene-related peptide type 1 receptor; calcitonin receptor like receptor; calcitonin receptor-like; calcitonin receptor-like receptor; CALCRL; CGRP receptor; CGRP type 1 receptor; Cgrp1 receptor; CGRPR; CLR; CRLR; RATCRLR; RNCLR

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10203, 25029

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Fischer Scientific

70-383-6

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Antigen:
H3.3 G34W oncohistone mutant

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
P84243

Gene Symbols:
H3-3A, H3-3B

Immunogen:
Peptide corresponding to human H3.3G34W [aa30-aa39]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, Immunocytochemistry, Western Blot

Clone:
4H32L4

Conjugate:
Unconjugated

Gene:
H3-3A

Gene Alias:
H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3.3; H3.3 G34W; H3.3A; H3.3B; H3/g; H3-3A; H3-3B; H3B; H3F3; H3F3A; H3F3B; H3FT; H3G34W; H3t; Histone 3.3; Histone cluster 3; Histone H3; Histone H3.3; Histone H3.3 G34W; Histone H3.3G34W; PP781

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3020, 3021

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid