70-356-8
SHP-1 Recombinant Rabbit Monoclonal Antibody (3H20L13), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 70-356-8-Each-of-1 | In Stock | ₹ 42,780.00 |
70-356-8 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,780.00
GST (18%): ₹ 7,700.40
Total Price: ₹ 50,480.40
Antigen
SHP-1
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide, pH 7.4
Gene Accession No.
P29350
Gene Symbols
PTPN6
Immunogen
Protein corresponding to human SHP-1 [aa243-aa541]
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot, Western Blot
Clone
3H20L13
Conjugate
Unconjugated
Gene
PTPN6
Gene Alias
70Z-SHP, EC 3.1.3.48, hcp, Hcph, hematopoietic cell phosphatase, hematopoietic cell protein-tyrosine phosphatase, HPTP1C, me, motheaten, protein tyrosine phosphatase, non-receptor type 6, protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, PTN6, Ptp1C, PTP-1C, Ptph6, PTPN6, PTPTY-42, SH2 phosphatase 1, SHP1, Shp-1, SHP-1L, SH-PTP1, Tyrosine-protein phosphatase non-receptor type 6
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5777
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody is predicted to react with Monkey, Horse, Cat
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- SHP-1 (PTPN6) is a non-receptor protein tyrosine phosphatase that is expressed primarily in hematopoietic cells
- The enzyme is composed of two SH2 domains, a tyrosine phosphatase catalytic domain, and a carboxy-terminal regulatory domain
- SHP-1 removes phosphates from target proteins to downregulate several tyrosine kinase-regulated pathways
- In hematopoietic cells, the amino-terminal SH2 domain of SHP-1 binds to tyrosine phosphorylated erythropoietin receptors (EpoR) to negatively regulate hematopoietic growth
- Overexpression of SHP-1 in epithelial cells results in dephosphorylation of the Ros receptor tyrosine kinase and subsequent downregulation of Ros-dependent cell proliferation and transformation
- Following ligand binding in myeloid cells, SHP-1 associates with the IL-3R beta chain and downregulates IL-3-induced tyrosine phosphorylation and cell proliferation.
Compare Similar Items
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Antigen: SHP-1
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.4
Gene Accession No.: P29350
Gene Symbols: PTPN6
Immunogen: Protein corresponding to human SHP-1 [aa243-aa541]
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot, Western Blot
Clone: 3H20L13
Conjugate: Unconjugated
Gene: PTPN6
Gene Alias: 70Z-SHP, EC 3.1.3.48, hcp, Hcph, hematopoietic cell phosphatase, hematopoietic cell protein-tyrosine phosphatase, HPTP1C, me, motheaten, protein tyrosine phosphatase, non-receptor type 6, protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, PTN6, Ptp1C, PTP-1C, Ptph6, PTPN6, PTPTY-42, SH2 phosphatase 1, SHP1, Shp-1, SHP-1L, SH-PTP1, Tyrosine-protein phosphatase non-receptor type 6
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5777
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SHP-1
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.4
Gene Accession No.:
P29350
Gene Symbols:
PTPN6
Immunogen:
Protein corresponding to human SHP-1 [aa243-aa541]
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot, Western Blot
Clone:
3H20L13
Conjugate:
Unconjugated
Gene:
PTPN6
Gene Alias:
70Z-SHP, EC 3.1.3.48, hcp, Hcph, hematopoietic cell phosphatase, hematopoietic cell protein-tyrosine phosphatase, HPTP1C, me, motheaten, protein tyrosine phosphatase, non-receptor type 6, protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, PTN6, Ptp1C, PTP-1C, Ptph6, PTPN6, PTPTY-42, SH2 phosphatase 1, SHP1, Shp-1, SHP-1L, SH-PTP1, Tyrosine-protein phosphatase non-receptor type 6
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5777
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: ALKBH5
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: Q3TSG4, Q6P6C2
Gene Symbols: ALKBH5
Immunogen: Protein corresponding to human ALKBH5 [aa66-aa292]
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 10H24L9
Conjugate: Unconjugated
Gene: ALKBH5
Gene Alias: ABH5; AlkB family member 5, RNA demethylase; alkB homolog 5, RNA demethylase; alkB, alkylation repair homolog 5; alkB, alkylation repair homolog 5 (E. coli); Alkbh5; Alkylated DNA repair protein alkB homolog 5; alpha-ketoglutarate-dependent dioxygenase alkB homolog 5; AW050020; AW215868; E130207K11; OFOXD; OFOXD1; oxoglutarate and iron-dependent oxygenase domain containing; probable alpha-ketoglutarate-dependent dioxygenase ABH5; RGD1309496; RNA demethylase ALKBH5
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 268420, 54890
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
ALKBH5
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
Q3TSG4, Q6P6C2
Gene Symbols:
ALKBH5
Immunogen:
Protein corresponding to human ALKBH5 [aa66-aa292]
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
10H24L9
Conjugate:
Unconjugated
Gene:
ALKBH5
Gene Alias:
ABH5; AlkB family member 5, RNA demethylase; alkB homolog 5, RNA demethylase; alkB, alkylation repair homolog 5; alkB, alkylation repair homolog 5 (E. coli); Alkbh5; Alkylated DNA repair protein alkB homolog 5; alpha-ketoglutarate-dependent dioxygenase alkB homolog 5; AW050020; AW215868; E130207K11; OFOXD; OFOXD1; oxoglutarate and iron-dependent oxygenase domain containing; probable alpha-ketoglutarate-dependent dioxygenase ABH5; RGD1309496; RNA demethylase ALKBH5
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
268420, 54890
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: 53BP1
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: Q12888
Gene Symbols: TP53BP1
Immunogen: Protein corresponding to human 53BP1 [aa241-aa440]
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: 7H14L12
Conjugate: Unconjugated
Gene: TP53BP1
Gene Alias: 53BP1; FLJ41424; m53BP1; MGC138366; murine p53-binding protein; p202; p53-binding protein 1; p53BP1; TDRD30; TP53; TP53-binding protein 1; Tp53bp1; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; Trp53bp1; tumor protein 53-binding protein, 1; tumor protein p53 binding protein 1; tumor protein p53-binding protein, 1; tumor suppressor p53-binding protein 1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7158
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
53BP1
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
Q12888
Gene Symbols:
TP53BP1
Immunogen:
Protein corresponding to human 53BP1 [aa241-aa440]
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
7H14L12
Conjugate:
Unconjugated
Gene:
TP53BP1
Gene Alias:
53BP1; FLJ41424; m53BP1; MGC138366; murine p53-binding protein; p202; p53-binding protein 1; p53BP1; TDRD30; TP53; TP53-binding protein 1; Tp53bp1; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; Trp53bp1; tumor protein 53-binding protein, 1; tumor protein p53 binding protein 1; tumor protein p53-binding protein, 1; tumor suppressor p53-binding protein 1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7158
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: EYA1
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: P97767, Q99502
Gene Symbols: EYA1
Immunogen: Peptides corresponding to human EYA1 [1) aa11-aa29 2) aa290-aa303]
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 24H60L7
Conjugate: Unconjugated
Gene: EYA1
Gene Alias: BOP; bor; BOS1; dog eared; EYA transcriptional coactivator and phosphatase 1; eya1; eya1 protein; Eyes absent; eyes absent 1; eyes absent 1 homolog; eyes absent 1 homolog (Drosophila); eyes absent homolog 1; MGC141875; OFC1; OTTHUMP00000195053; wu:fc13c10; zgc:100770
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 14048, 2138
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
EYA1
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
P97767, Q99502
Gene Symbols:
EYA1
Immunogen:
Peptides corresponding to human EYA1 [1) aa11-aa29 2) aa290-aa303]
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
24H60L7
Conjugate:
Unconjugated
Gene:
EYA1
Gene Alias:
BOP; bor; BOS1; dog eared; EYA transcriptional coactivator and phosphatase 1; eya1; eya1 protein; Eyes absent; eyes absent 1; eyes absent 1 homolog; eyes absent 1 homolog (Drosophila); eyes absent homolog 1; MGC141875; OFC1; OTTHUMP00000195053; wu:fc13c10; zgc:100770
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
14048, 2138
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid