7068927
CD153 Monoclonal Antibody (RM153), PE, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
CD153
Concentration
0.2 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Alias
CD153; CD153 antigen; CD30 antigen ligand; CD30 ligand; Cd30l; CD30-L; Cd30lg; CD30ligand; Tnfsf8; TNLG3A; tumor necrosis factor (ligand) superfamily member 8; tumor necrosis factor (ligand) superfamily, member 8; tumor necrosis factor ligand 3A; tumor necrosis factor ligand superfamily member 8; tumor necrosis factor superfamily member 8
Gene Symbols
Tnfsf8
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Gene
Tnfsf8
Clone
RM153
Applications
Flow Cytometry
Conjugate
PE
Host Species
Rat
Target Species
Mouse
Gene Accession No.
P32972
Gene ID (Entrez)
21949
Isotype
IgG2b κ
Purification Method
Affinity chromatography
Product Type
Antibody
Related Products
Description
- Description: The RM153 monoclonal antibody reacts with mouse CD153 (CD30 ligand)
- This 40 kDa cell surface receptor, a type II transmembrane protein, is a member of the TNF superfamily
- Interaction of CD30 with CD153 plays an important role in T cell activation/costimulation
- Expression of CD153 on T cells does not appear to require costimulation through CD28 and is upregulated via TCR engagement and peaks 24-48 hours after activation
- Signaling through CD153 is important in costimulation of pre-activated T cells
- Applications Reported: The RM153 antibody has been reported for use in flow cytometric analysis
- Applications Tested: The RM153 antibody has been tested by flow cytometric analysis of activated mouse splenocytes
- This can be used at less than or equal to 0.125 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
- Filtration: 0.2 μm post-manufacturing filtered
- The ligand for CD30 is CD30L (CD153)
- The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death
- CD30 has a critical role in the pathophysiology of Hodgkin's disease and other CD30+ lymphomas
- CD30 acts as a costimulatory molecule in thymic negative selection
- In addition to its expression on Hodgkin's and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin's lymphomas (including Burkitt's lymphomas), virus-infected T and B cells, and on normal T and B cells after activation
- In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that coexpress CD45RO and the IL4 receptor.
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Antigen: CD153
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: CD153; CD153 antigen; CD30 antigen ligand; CD30 ligand; Cd30l; CD30-L; Cd30lg; CD30ligand; Tnfsf8; TNLG3A; tumor necrosis factor (ligand) superfamily member 8; tumor necrosis factor (ligand) superfamily, member 8; tumor necrosis factor ligand 3A; tumor necrosis factor ligand superfamily member 8; tumor necrosis factor superfamily member 8
Gene Symbols: Tnfsf8
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: Tnfsf8
Clone: RM153
Applications: Flow Cytometry
Conjugate: PE
Host Species: Rat
Target Species: Mouse
Gene Accession No.: P32972
Gene ID (Entrez): 21949
Isotype: IgG2b κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD153
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
CD153; CD153 antigen; CD30 antigen ligand; CD30 ligand; Cd30l; CD30-L; Cd30lg; CD30ligand; Tnfsf8; TNLG3A; tumor necrosis factor (ligand) superfamily member 8; tumor necrosis factor (ligand) superfamily, member 8; tumor necrosis factor ligand 3A; tumor necrosis factor ligand superfamily member 8; tumor necrosis factor superfamily member 8
Gene Symbols:
Tnfsf8
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
Tnfsf8
Clone:
RM153
Applications:
Flow Cytometry
Conjugate:
PE
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
P32972
Gene ID (Entrez):
21949
Isotype:
IgG2b κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: CD158f
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias: CD158; CD158F; CD158f1; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A; killer cell immunoglobulin-like receptor 2DL5A; killer cell immunoglobulin-like receptor KIR2DL5A; killer cell immunoglobulin-like receptor two domains long cytoplasmic tail 5; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A; killer-cell Ig-like receptor; KIR2DL; KIR2DL5; KIR2DL5.1; KIR2DL5.3; KIR2DL5A; NKAT; NKAT1
Gene Symbols: KIR2DL5A
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: KIR2DL5A
Clone: UP-R1
Applications: Flow Cytometry
Conjugate: PE
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q8N109
Gene ID (Entrez): 57292
Isotype: IgG1
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD158f
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
CD158; CD158F; CD158f1; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A; killer cell immunoglobulin-like receptor 2DL5A; killer cell immunoglobulin-like receptor KIR2DL5A; killer cell immunoglobulin-like receptor two domains long cytoplasmic tail 5; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A; killer-cell Ig-like receptor; KIR2DL; KIR2DL5; KIR2DL5.1; KIR2DL5.3; KIR2DL5A; NKAT; NKAT1
Gene Symbols:
KIR2DL5A
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
KIR2DL5A
Clone:
UP-R1
Applications:
Flow Cytometry
Conjugate:
PE
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q8N109
Gene ID (Entrez):
57292
Isotype:
IgG1
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: CD160
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: AU045688; BY55; CD160; CD160 antigen; CD160 antigen, soluble form; CD160 molecule; CD160 transmembrane isoform; CD160-delta Ig; natural killer cell BY55; natural killer cell receptor; natural killer cell receptor BY55; natural killer cell receptor, immunoglobulin superfamily member; NK1; NK28; RGD1563598
Gene Symbols: CD160
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: CD160
Clone: eBioCNX46-3 (CNX46-3)
Applications: Flow Cytometry
Conjugate: PE
Host Species: Rat
Target Species: Mouse
Gene Accession No.: O88875
Gene ID (Entrez): 54215
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD160
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
AU045688; BY55; CD160; CD160 antigen; CD160 antigen, soluble form; CD160 molecule; CD160 transmembrane isoform; CD160-delta Ig; natural killer cell BY55; natural killer cell receptor; natural killer cell receptor BY55; natural killer cell receptor, immunoglobulin superfamily member; NK1; NK28; RGD1563598
Gene Symbols:
CD160
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
CD160
Clone:
eBioCNX46-3 (CNX46-3)
Applications:
Flow Cytometry
Conjugate:
PE
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
O88875
Gene ID (Entrez):
54215
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: CD166 (ALCAM)
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: activated leukocyte cell adhesion molecule; AI853494; ALCAM; BEN; CD166; CD166 antigen; cell adhesion molecule; DM-GRASP; FLJ38514; HB2; KG-CAM; MEMD; MGC71733; MuSC; Protein DM-GRASP; Protein MEMD; SB-10 antigen; SC1; unnamed protein product
Gene Symbols: ALCAM
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: ALCAM
Clone: eBioALC48
Applications: Flow Cytometry
Conjugate: PE
Host Species: Rat
Target Species: Mouse
Gene Accession No.: Q61490
Gene ID (Entrez): 11658
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD166 (ALCAM)
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
activated leukocyte cell adhesion molecule; AI853494; ALCAM; BEN; CD166; CD166 antigen; cell adhesion molecule; DM-GRASP; FLJ38514; HB2; KG-CAM; MEMD; MGC71733; MuSC; Protein DM-GRASP; Protein MEMD; SB-10 antigen; SC1; unnamed protein product
Gene Symbols:
ALCAM
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
ALCAM
Clone:
eBioALC48
Applications:
Flow Cytometry
Conjugate:
PE
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
Q61490
Gene ID (Entrez):
11658
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Product Type:
Antibody