7069308

CD49e (Integrin alpha 5) Monoclonal Antibody (eBioHMa5-1 (HMa5-1)), eBioscience™, Invitrogen™

Armenian Hamster Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD49e (Integrin alpha 5)

Concentration

0.5 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Alias

2-phospho-D-glycerate hydro-lyase; alpha enolase like 1; Alpha-enolase; alpha-enolase; c-myc promoter-binding protein-1; CD49 antigen-like family member E; Cd49e; C-myc promoter-binding protein; ENO1; ENO1L1; Enolase 1; enolase 1, (alpha); enolase-alpha; epididymis secretory protein Li 17; fibronectin receptor alpha polypeptide; fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; FNRA; HEL-S-17; integrin alpha 5; integrin alpha 5 (fibronectin receptor alpha); integrin alpha-5; Integrin alpha-5 heavy chain; Integrin alpha-5 light chain; Integrin alpha-F; integrin subunit alpha 5; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); ITGA5; Itga5_retired; MBP-1; MBPB1; MPB1; MPB-1; MYC promoter-binding protein 1; NNE; Non-neural enolase; phosphopyruvate hydratase; Plasminogen-binding protein; PPH; tau-crystallin; very late activation protein 5, alpha subunit; VLA5; VLA-5; VLA5A

Gene Symbols

Itga5

Primary or Secondary

Primary

Content And Storage

4° C

Gene

Itga5

Clone

eBioHMa5-1 (HMa5-1)

Applications

Flow Cytometry, Functional Assay, Immunoprecipitation

Conjugate

Unconjugated

Host Species

Armenian Hamster

Target Species

Mouse, Rat

Gene Accession No.

P11688

Gene ID (Entrez)

16402, 315346

Isotype

IgG

Purification Method

Affinity chromatography

Product Type

Antibody

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Description

  • Description: The eBioHMalpha5-1 monoclonal antibody reacts with mouse and rat CD49e, also known as integrin alpha5 or VLA-5A
  • CD49e is a member of the integrin alpha chain family, and binds with CD29 (integrin beta1) to form the receptor VLA-5, which binds the ligands fibronectin and fibrinogen
  • CD49e is a type I, single-pass membrane protein, with a molecular weight of 135 kDa, and is expressed on multiple cell types including thymocytes, mast cells, activated T cells and splenic B cells
  • In addition to its role in adhesion, VLA-5 contributes to T-cell co-stimulation
  • The eBioHMalpha5-1 monoclonal antibody has been demonstrated to interfere with VLA-5-mediated cell adhesion, and with the degranulation of IgE-sensitized rat RBL cells stimulated on fibronectin-coated plates
  • Furthermore, HMalpha5-1 injected into mice subcutaneously, along with anti-CD49d and anti-CD61, is able to inhibit passive cutaneous anaphylaxis
  • Applications Reported: This eBioHMa5-1 (HMa5-1) antibody has been reported for use in flow cytometric analysis, and immunoprecipitation
  • (Please use Functional Grade purified eBioHMa5-1 (HMa5-1), cat
  • 16-0493, in functional assays.)
  • Applications Tested: This eBioHMa5-1 (HMa5-1) antibody has been tested by flow cytometric analysis of mouse bone marrow cells
  • This can be used at less than or equal to 1 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • The product of this gene belongs to the integrin alpha chain family
  • Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain
  • This gene encodes the integrin alpha 5 chain
  • Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor
  • In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

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Antigen:
CD49e (Integrin alpha 5)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
2-phospho-D-glycerate hydro-lyase; alpha enolase like 1; Alpha-enolase; alpha-enolase; c-myc promoter-binding protein-1; CD49 antigen-like family member E; Cd49e; C-myc promoter-binding protein; ENO1; ENO1L1; Enolase 1; enolase 1, (alpha); enolase-alpha; epididymis secretory protein Li 17; fibronectin receptor alpha polypeptide; fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; FNRA; HEL-S-17; integrin alpha 5; integrin alpha 5 (fibronectin receptor alpha); integrin alpha-5; Integrin alpha-5 heavy chain; Integrin alpha-5 light chain; Integrin alpha-F; integrin subunit alpha 5; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); ITGA5; Itga5_retired; MBP-1; MBPB1; MPB1; MPB-1; MYC promoter-binding protein 1; NNE; Non-neural enolase; phosphopyruvate hydratase; Plasminogen-binding protein; PPH; tau-crystallin; very late activation protein 5, alpha subunit; VLA5; VLA-5; VLA5A

Gene Symbols:
Itga5

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
Itga5

Clone:
eBioHMa5-1 (HMa5-1)

Applications:
Flow Cytometry, Functional Assay, Immunoprecipitation

Conjugate:
Unconjugated

Host Species:
Armenian Hamster

Target Species:
Mouse, Rat

Gene Accession No.:
P11688

Gene ID (Entrez):
16402, 315346

Isotype:
IgG

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
CD49f (Integrin alpha 6)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
5033401O05Rik; AI115430; Alpha6p; CD49 antigen-like family member F; CD49f; DKFZp686J01244; FLJ18737; integrin alpha 6; integrin alpha-6; Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; integrin alpha6B; integrin subunit alpha 6; integrin, alpha 6; Itga6; ITGA6B; LOW QUALITY PROTEIN: integrin alpha-6; Processed integrin alpha-6; VLA-6

Gene Symbols:
Itga6

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
Itga6

Clone:
eBioGoH3 (GoH3)

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Human, Mouse

Gene Accession No.:
P23229, Q61739

Gene ID (Entrez):
16403, 3655

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
CD51 (Integrin alpha V)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
1110004F14Rik; 2610028E01Rik; alpha v integrin; antigen identified by monoclonal antibody L230; Cd51; CD61; D430040G12Rik; Dnmt3l-ps1 pseudogene; GP3A; GPIIIa; integrin alpha V; integrin alpha-V; Integrin alpha-V heavy chain; Integrin alpha-V light chain; integrin alphaVbeta3; integrin subunit alpha V; integrin, alpha V; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); ITGAV; ITGB3; MSK8; Vitronectin receptor; vitronectin receptor alpha polypeptide (VNRA); vitronectin receptor subunit alpha; VNR; VNRA; VTNR

Gene Symbols:
ITGAV

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
ITGAV

Clone:
RMV-7

Applications:
Flow Cytometry, Functional Assay, Immunoprecipitation, Neutralization

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P43406

Gene ID (Entrez):
16410

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
CD54 (ICAM-1)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
__

Gene Alias:
__

Gene Symbols:
__

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
__

Clone:
YN1/1.7.4

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry, Neutralization

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P13597

Gene ID (Entrez):
15894

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Product Type:
Antibody