7069394
PDE3B Monoclonal Antibody (SMCP3B), eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
PDE3B
Concentration
0.5 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Alias
9830102A01Rik; AI847709; CGIP1; CGI-PDE B; CGIPDE1; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cyclic GMP-inhibited phosphodiesterase B; cyclic nucleotide phosphodiesterase; HcGIP1; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B; PDE3B; phosphodiesterase 3B; phosphodiesterase 3B cGMP inhibited; phosphodiesterase 3B, cGMP-inhibited
Gene Symbols
PDE3B
Primary or Secondary
Primary
Content And Storage
4° C
Gene
PDE3B
Clone
SMCP3B
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Rat
Target Species
Mouse
Gene Accession No.
Q61409
Gene ID (Entrez)
18576
Isotype
IgG2a κ
Purification Method
Affinity chromatography
Product Type
Antibody
Related Products
Description
- Description: Cyclic nucleotide phosphodiesterases (PDE) catalyze the hydrolysis of cAMP and cGMP thereby regulating the effects of these second messengers
- There are several families of PDE which share common structural organization
- The PDE3 family has two members, 3A and 3B that are products of two separate genes
- PDE3B (∽130 kDa) is expressed predominantly in adipose tissue and lymphocytes, while PDE3A (∽120 kDa) is expressed predominantly in platelets and heart tissue
- The monoclonal antibody SMCP3B reacts with mouse PDE3B
- The SMCP3B antibody was generated against amino acids 643-1100 in the C-terminus and does not cross-react with mouse PDE3A, as determined by western blot analysis of lysates of mouse heart tissue
- The SMCP3B antibody does not cross-react with human PDE3B
- Applications Reported: This SMCP3B antibody has been reported for use in immunoblotting (WB)
- Applications Tested: This SMCP3B antibody has been tested by immunoblotting of mouse lymph node cells and mouse heart under reducing conditions
- It can be used at 1-5 μg/mL
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes
- May play a role in fat metabolism
- Regulates cAMP binding of RAPGEF3
- Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.
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Antigen: PDE3B
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: 9830102A01Rik; AI847709; CGIP1; CGI-PDE B; CGIPDE1; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cyclic GMP-inhibited phosphodiesterase B; cyclic nucleotide phosphodiesterase; HcGIP1; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B; PDE3B; phosphodiesterase 3B; phosphodiesterase 3B cGMP inhibited; phosphodiesterase 3B, cGMP-inhibited
Gene Symbols: PDE3B
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: PDE3B
Clone: SMCP3B
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rat
Target Species: Mouse
Gene Accession No.: Q61409
Gene ID (Entrez): 18576
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
PDE3B
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
9830102A01Rik; AI847709; CGIP1; CGI-PDE B; CGIPDE1; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cyclic GMP-inhibited phosphodiesterase B; cyclic nucleotide phosphodiesterase; HcGIP1; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B; PDE3B; phosphodiesterase 3B; phosphodiesterase 3B cGMP inhibited; phosphodiesterase 3B, cGMP-inhibited
Gene Symbols:
PDE3B
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
PDE3B
Clone:
SMCP3B
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
Q61409
Gene ID (Entrez):
18576
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: CD4
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen
Gene Symbols: CD4
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: CD4
Clone: N1UG0
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P01730
Gene ID (Entrez): 920
Isotype: IgG2b κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD4
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen
Gene Symbols:
CD4
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
CD4
Clone:
N1UG0
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P01730
Gene ID (Entrez):
920
Isotype:
IgG2b κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: CD324 (E-Cadherin)
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: AA960649; ARC-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, epithelial; cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDH1; CDHE; cell adhesion molecule; cell-CAM 120/80; ECAD; E-cad; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Ecadherin; E-cadherin; E-cadherin 1; E-cadherin precursor; Epithelial cadherin; hab; half baked; LCAM; L-CAM; Um; UVO; Uvomorulin
Gene Symbols: CDH1
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: CDH1
Clone: DECMA-1
Applications: ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rat
Target Species: Canine, Human, Mouse
Gene Accession No.: F1PAA9, P09803, P12830
Gene ID (Entrez): 12550, 442858, 999
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD324 (E-Cadherin)
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
AA960649; ARC-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, epithelial; cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDH1; CDHE; cell adhesion molecule; cell-CAM 120/80; ECAD; E-cad; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Ecadherin; E-cadherin; E-cadherin 1; E-cadherin precursor; Epithelial cadherin; hab; half baked; LCAM; L-CAM; Um; UVO; Uvomorulin
Gene Symbols:
CDH1
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
CDH1
Clone:
DECMA-1
Applications:
ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rat
Target Species:
Canine, Human, Mouse
Gene Accession No.:
F1PAA9, P09803, P12830
Gene ID (Entrez):
12550, 442858, 999
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: Rat IgG2b kappa
Concentration: 0.5 mg/mL
Classification: __
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: IgG2; Immunoglobulin G; Immunoglobulin G2; ImmunoglobulinG; ImmunoglobulinG2
Gene Symbols: __
Primary or Secondary: Isotype Control (Primary)
Content And Storage: 4° C
Gene: __
Clone: eB149/10H5
Applications: Control, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rat
Target Species: Not Applicable
Gene Accession No.: __
Gene ID (Entrez): __
Isotype: IgG2b κ
Purification Method: Affinity chromatography
Product Type: __
Antigen:
Rat IgG2b kappa
Concentration:
0.5 mg/mL
Classification:
__
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
IgG2; Immunoglobulin G; Immunoglobulin G2; ImmunoglobulinG; ImmunoglobulinG2
Gene Symbols:
__
Primary or Secondary:
Isotype Control (Primary)
Content And Storage:
4° C
Gene:
__
Clone:
eB149/10H5
Applications:
Control, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rat
Target Species:
Not Applicable
Gene Accession No.:
__
Gene ID (Entrez):
__
Isotype:
IgG2b κ
Purification Method:
Affinity chromatography
Product Type:
__