7069436

EOMES Monoclonal Antibody (Dan11mag), eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

EOMES

Concentration

0.5 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Alias

C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2

Gene Symbols

Eomes

Primary or Secondary

Primary

Content And Storage

4° C

Gene

Eomes

Clone

Dan11mag

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Rat

Target Species

Mouse

Gene Accession No.

O54839

Gene ID (Entrez)

13813

Isotype

IgG2a κ

Purification Method

Affinity chromatography

Product Type

Antibody

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Description

  • Description: This Dan11mag antibody recognizes Eomesodermin (Eomes), also known as T-box brain 2 (TBR2)
  • Eomes is a T-box transcription factor that is highly homologous to T-bet, which is essential during trophoblast development and gastrulation in most vertebrates
  • In the immune system, Eomes controls the differentiation of effector and memory CD8+ T cells, as well as natural killer (NK) cells
  • Expression of Eomes in these cells correlates with high expression of CD122, the common beta-chain of the IL-2R and IL-15R
  • Applications Reported: This Dan11mag antibody has been reported for use in immunohistochemistry of formalin-fixed paraffin embedded tissue sections, intracellular staining followed by flow cytometric analysis, and western blotting
  • (Fluorochrome conjugated Dan11mag is recommended for use in intracellular flow cytometry.)
  • Applications Tested: This Dan11mag antibody has been tested by intracellular staining followed by flow cytometric analysis of mouse splenocytes and/or western blotting at 5 μg/mL
  • This Dan11mag antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded mouse tissue using low pH antigen retrieval at less than or equal to 5 μg/mL
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Purity: Greater than 90%, as determined by SDS-PAGE
  • Aggregation: Less than 10%, as determined by HPLC
  • Filtration: 0.2 μm post-manufacturing filtered
  • TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box
  • T-box genes encode transcription factors involved in the regulation of developmental processes
  • A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation
  • TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.

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Antigen:
EOMES

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2

Gene Symbols:
Eomes

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
Eomes

Clone:
Dan11mag

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
O54839

Gene ID (Entrez):
13813

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
Galectin 3

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
35 kDa lectin; advanced glycation end-product receptor 3; AGE-R3; beta-galactosides-binding lectin; carbohydrate-binding protein 35; CBP 35; CBP30; CBP-30; CBP35; epsilon BP; gal3; gal-3; galactose-specific lectin 3; Galactoside-binding protein; GALBP; galectin 3; Galectin3; galectin-3; GALIG; GBP; IgE binding protein; igE-binding protein; L-29; L31; L-31; L-34; L-34 galactoside-binding lectin; Laminin-binding protein; lectin galactoside-binding soluble 3; lectin galactoside-binding soluble 3 protein; lectin L-29; lectin, galactose binding, soluble 3; lectin, galactoside binding soluble 3; lectin, galactoside-binding, soluble, 3; lectin, galactoside-binding, soluble, 3 (galectin 3); LGALS2; Lgals3; MAC2; Mac-2; Mac-2 antigen

Gene Symbols:
LGALS3

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
LGALS3

Clone:
eBioM3/38 (M3/38)

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Human, Mouse

Gene Accession No.:
P16110, P17931

Gene ID (Entrez):
16854, 3958

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
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Concentration:
0.5 mg/mL

Classification:
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Form:
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Regulatory Status:
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Formulation:
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Gene Alias:
bHLHc3; Class C basic helix-loop-helix protein 3; MYF4; Myf-4; myo; MYOD1-related protein; MYOG; Myogenic factor 4; Myogenic factor-4; myogenin; myogenin (myogenic factor 4)

Gene Symbols:
MYOG

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
MYOG

Clone:
F5D

Applications:
Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Canine, Human, Mouse, Rat

Gene Accession No.:
P12979, P15173, P20428

Gene ID (Entrez):
17928, 29148, 4656, 490224

Isotype:
IgG1

Purification Method:
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Product Type:
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Antigen:
Plexin-B2

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
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Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
Debt; differentially expressed in brain tumors; dJ402G11.3; KIAA0315; MM1; MM1KIAA0315dJ402G11.3; Nbla00445; PLEXB2; plexin B2; plexin-B2; PLXNB2

Gene Symbols:
PLXNB2

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
PLXNB2

Clone:
eBio3E7 (3E7)

Applications:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation

Conjugate:
Unconjugated

Host Species:
Armenian Hamster

Target Species:
Mouse

Gene Accession No.:
B2RXS4

Gene ID (Entrez):
140570

Isotype:
IgG

Purification Method:
Affinity chromatography

Product Type:
Antibody