7069915

IL-6 Monoclonal Antibody (MQ2-13A5), Functional Grade, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

IL-6

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with no preservative; pH 7.2

Gene Alias

B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6

Gene Symbols

Il6

Primary or Secondary

Primary

Content And Storage

4° C

Gene

Il6

Clone

MQ2-13A5

Applications

ELISA, Functional Assay, Neutralization

Conjugate

Functional Grade

Host Species

Rat

Target Species

Human

Gene Accession No.

P05231

Gene ID (Entrez)

3569

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Product Type

Antibody

Description

  • Description: The MQ2-13A5 antibody reacts with human interleukin-6 (IL-6), a 21-28 kDa cytokine secreted by a variety of cell types
  • Applications Reported: This MQ2-13A5 antibody has been reported for use in cytokine neutralization, ELISPOT, and ELISA capture
  • Applications Tested: The MQ2-13A5 antibody has been tested for neutralizing IL-6 binding and biological activity
  • Storage and handling: Use in a sterile environment
  • Filtration: 0.2 μm post-manufacturing filtered
  • Purity: Greater than 90%, as determined by SDS-PAGE
  • Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay
  • Aggregation: Less than 10%, as determined by HPLC
  • IL-6 is a gene that encodes a cytokine that plays a role in inflammation and the maturation of B cells
  • The protein produced by this gene is an endogenous pyrogen that can induce fever in people with autoimmune diseases or infections
  • The gene is primarily expressed at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha
  • The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis
  • Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2)
  • Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.

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7069915

Rat Monoclonal Antibody...


Antigen:
IL-6

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative; pH 7.2

Gene Alias:
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6

Gene Symbols:
Il6

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
Il6

Clone:
MQ2-13A5

Applications:
ELISA, Functional Assay, Neutralization

Conjugate:
Functional Grade

Host Species:
Rat

Target Species:
Human

Gene Accession No.:
P05231

Gene ID (Entrez):
3569

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Concentration:
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Classification:
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Form:
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Regulatory Status:
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Formulation:
PBS with no preservative; pH 7.2

Gene Alias:
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF

Gene Symbols:
IL10

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
IL10

Clone:
JES3-9D7

Applications:
ELISA, Functional Assay, Neutralization

Conjugate:
Functional Grade

Host Species:
Rat

Target Species:
Human

Gene Accession No.:
P22301

Gene ID (Entrez):
3586

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
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Antigen:
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Concentration:
1 mg/mL

Classification:
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Form:
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Regulatory Status:
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Formulation:
PBS with no preservative; pH 7.2

Gene Alias:
Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A

Gene Symbols:
IL17A

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
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Clone:
eBioMM17F3

Applications:
Functional Assay, Neutralization

Conjugate:
Functional Grade

Host Species:
Mouse

Target Species:
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Gene ID (Entrez):
16171

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
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TNF alpha

Concentration:
1 mg/mL

Classification:
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Form:
Liquid

Regulatory Status:
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Formulation:
PBS with no preservative; pH 7.2

Gene Alias:
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor

Gene Symbols:
Tnf

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
Tnf

Clone:
MP6-XT22

Applications:
Functional Assay, Neutralization

Conjugate:
Functional Grade

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P06804

Gene ID (Entrez):
21926

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody