7090011

CD31 (PECAM-1) Monoclonal Antibody (WM-59 (WM59)), APC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD31 (PECAM-1)

Concentration

5 μL/Test

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias

C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule

Gene Symbols

Pecam1

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

Pecam1

Clone

WM-59 (WM59)

Applications

Flow Cytometry

Conjugate

APC

Host Species

Mouse

Target Species

Human

Gene Accession No.

P16284

Gene ID (Entrez)

5175

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Product Type

Antibody

Description

  • Description: The WM59 monoclonal antibody reacts with human CD31, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1) and gpIIa
  • This 130-140 kDa surface protein is expressed by endothelial cells and at low levels on leukocytes and platelets
  • It has been reported that CD38 binds to CD31
  • Homotypic interaction of CD31 is important in adhesion, cell-cell and cell-matrix interaction, and signal transduction
  • Applications Reported: The WM-59 (WM59) antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This WM-59 (WM59) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
  • This can be used at 5 μL (0.5 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases
  • CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells
  • N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions
  • CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis
  • It is one of key regulatory molecules in vascular system.

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Img

Fischer Scientific

7090011

Mouse Monoclonal Antibody...


Antigen:
CD31 (PECAM-1)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule

Gene Symbols:
Pecam1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Pecam1

Clone:
WM-59 (WM59)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P16284

Gene ID (Entrez):
5175

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7090012

Mouse Monoclonal Antibody...


Antigen:
CD32b

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
AI528646; CD32; CD32 receptor 2; CD32 receptor 2a; CD32 receptor 2b; CD32A; CD32B; CDw32; F630109E10Rik; Fc fragment of IgG receptor IIb; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); fc gamma receptor IIB; Fc gamma RIIb; Fc receptor, IgG, low affinity IIb; Fc[g]RII; FCG2; FC-gamma RII; fc-gamma RII-a; Fc-gamma RII-b; Fc-gamma-RII; fc-gamma-RIIa; FcgammaRIIB; fc-gamma-RIIb; FcgammaRIIB2; FcGR; Fcgr2; Fcgr2a; FCGR2A1; FCGR2B; FcgRII; Fcr-2; Fcr-3; fcRII; fcRII-a; fcRII-b; FGFR2B; IGFR2; IgG Fc receptor II beta; igG Fc receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II; low affinity immunoglobulin gamma Fc region receptor II-b; Ly-17; LyM-1; Ly-m20; Lymphocyte antigen 17

Gene Symbols:
FCGR2B

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
FCGR2B

Clone:
AT130-2

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Mouse

Target Species:
Mouse

Gene Accession No.:
P08101

Gene ID (Entrez):
14130

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7090013

Mouse Monoclonal Antibody...


Antigen:
CD32

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
CD32; CD32 receptor 2; CD32 receptor 2a; CD32A; CD32B; CD32C; CDW32; Fc fragment of IgG receptor IIa; Fc fragment of IgG receptor IIb; Fc fragment of IgG receptor IIc (gene/pseudogene); Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc fragment of IgG, low affinity IIa, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc fragment of IgG, low affinity IIc, receptor for (CD32); Fc gamma receptor II; Fc gamma receptor IIa; Fc gamma receptor IIb; Fc gamma receptor IIC; Fc gamma RIIb; FCG2; Fc-gamma receptor II; fc-gamma RII; Fc-gamma RII-a; fc-gamma RII-b; Fc-gamma RII-c; fc-gamma-RIIa; Fc-gamma-RIIb; fc-gamma-RIIc; Fc-gamma-RII-D; FcGR; FCGR2; FCGR2A; FCGR2A1; FCGR2B; FCGR2C; fcRII; fcRII-a; fcRII-b; FCRIIC; FGFR2B; IGFR2; IgG Fc fragment receptor; IgG Fc gamma receptor II; igG Fc receptor II; IgG Fc receptor II-a; igG Fc receptor II-b; IgG Fc receptor II-c; Immunoglobulin G Fc receptor II; immunoglobulin G Fc receptor II-c; low affinity immunoglobulin gamma Fc region receptor II; Low affinity immunoglobulin gamma Fc region receptor II-a; low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; MGC23887; MGC30032; RP11-5K23.6; soluble receptor; boFcRII-2

Gene Symbols:
FCGR2A, FCGR2B, FCGR2C

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
__

Clone:
6C4 (CD32)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P12318, P31994, P31995

Gene ID (Entrez):
2212, 2213, 9103

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7090014

Mouse Monoclonal Antibody...


Antigen:
CD33

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3

Gene Symbols:
CD33

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CD33

Clone:
WM-53 (WM53)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P20138

Gene ID (Entrez):
945

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody