7090050

CD62P (P-Selectin) Monoclonal Antibody (Psel.KO2.3), APC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD62P (P-Selectin)

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Alias

CD62; CD62 antigen-like family member P; CD62P; CD62P antigen; CD62P; CD62 homolog; FLJ45155; GMP140; GMP-140; GMRP; Granule membrane protein 140; granule membrane protein 140kDa; granulocyte membrane protein; Grmp; LECAM3; leukocyte-endothelial cell adhesion molecule 3; PADGEM; Platelet activation dependent granule-external membrane protein; platelet alpha-granule membrane protein; PSEL; PSELECT; P-selectin; P-selectin precursor; RP1-86F14.2; selectin P; selectin P (granule membrane protein 140kDa, antigen CD62); selectin, platelet; Selp

Gene Symbols

SELP

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

SELP

Clone

Psel.KO2.3

Applications

Flow Cytometry

Conjugate

APC

Host Species

Mouse

Target Species

Human, Mouse

Gene Accession No.

P16109, Q01102

Gene ID (Entrez)

20344, 6403

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Product Type

Antibody

Related Products

Img

Fischer Scientific

50-112-3059

--

Img

Fischer Scientific

50-112-8644

--

Img

Fischer Scientific

50-112-8950

--

Img

Fischer Scientific

7162177

Mouse Monoclonal Antibody...

Img

Fischer Scientific

7069844

Mouse Monoclonal Antibody...

Img

Fischer Scientific

50-143-65

--

Img

Fischer Scientific

50-143-66

--

Img

Fischer Scientific

7090360

Rat Monoclonal Antibody...

Description

  • Description: The Psel.KO2.3 monoclonal antibody reacts with mouse CD62P (also known as P-selectin and GMP-140), a 140-kDa cell adhesion molecule that can be induced on endothelial cells and platelets
  • During inflammation, this selectin mediates adhesion of monocytes and neutrophils to activated platelets, as well as leukocyte rolling on endothelial cells
  • The major ligand for CD62P on neutrophils is P-selectin glycoprotein ligand-1 (PSGL-1)
  • This monoclonal antibody recognizes an epitope that is conserved across several species (e.g
  • mouse, human, and rat) and has not been reported to block cell adhesion
  • Applications Reported: This Psel.KO2.3 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This Psel.KO2.3 antibody has been tested by flow cytometric analysis on thrombin-activated human platelets
  • This can be used at less than or equal to 0.25 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling
  • P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets
  • From there, it can be rapidly brought to the cell surface after exposure to thrombin, histamine, complement 5a, Ca21 ionophores, or adenosine diphosphate
  • P-selectin protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes
  • P-selectin plays an important role in adhesive processes between leucocytes and endothelial cells, and is a calcium dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens found on neutrophils and monocytes
  • P-selectin is constitutively expressed in inflammation and contributes to atherogenesis, thrombosis and tissue destruction
  • Clinically, P-selectin is used to distinguish heparin induced thrombocytopenia with and without thrombosis.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7090050

Mouse Monoclonal Antibody...


Antigen:
CD62P (P-Selectin)

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
CD62; CD62 antigen-like family member P; CD62P; CD62P antigen; CD62P; CD62 homolog; FLJ45155; GMP140; GMP-140; GMRP; Granule membrane protein 140; granule membrane protein 140kDa; granulocyte membrane protein; Grmp; LECAM3; leukocyte-endothelial cell adhesion molecule 3; PADGEM; Platelet activation dependent granule-external membrane protein; platelet alpha-granule membrane protein; PSEL; PSELECT; P-selectin; P-selectin precursor; RP1-86F14.2; selectin P; selectin P (granule membrane protein 140kDa, antigen CD62); selectin, platelet; Selp

Gene Symbols:
SELP

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
SELP

Clone:
Psel.KO2.3

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Mouse

Target Species:
Human, Mouse

Gene Accession No.:
P16109, Q01102

Gene ID (Entrez):
20344, 6403

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7090052

Rat Monoclonal Antibody...


Antigen:
CD63

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
C75951; CD 63; Cd63; CD63 antigen; CD63 antigen (melanoma 1 antigen); Cd63 molecule; CD63 protein; granulophysin; LAMP-3; Lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; mast cell antigen AD1; ME491; melanoma 1 antigen; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; Ocular melanoma-associated antigen; OMA81H; Tetraspanin-30; TSPAN30; tspan-30

Gene Symbols:
CD63

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CD63

Clone:
NVG-2

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P41731

Gene ID (Entrez):
12512

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7090053

Mouse Monoclonal Antibody...


Antigen:
CD66b

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
carcinoembryonic antigen CGM6; carcinoembryonic antigen gene family member 6; carcinoembryonic antigen related cell adhesion molecule 8; carcinoembryonic antigen-related cell adhesion molecule 8; CD66b; CD67; CD67 antigen; CEACAM8; CGM6; NCA-95; non-specific cross-reacting antigen NCA-95

Gene Symbols:
CEACAM8

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CEACAM8

Clone:
G10F5

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P31997

Gene ID (Entrez):
1088

Isotype:
IgM κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7090056

Mouse Monoclonal Antibody...


Antigen:
CD69

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
5830438K24Rik; Activation inducer molecule; activation inducer molecule (AIM/CD69); AI452015; AIM; BL-AC/P26; CD69; CD69 antigen; CD69 antigen (p60, early T-cell activation antigen); CD69 molecule; CLEC2C; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; EA1; early activation antigen CD69; early lymphocyte activation antigen; early T-cell activation antigen p60; GP32/28; leukocyte surface antigen Leu-23; MLR-3; VEA; Very Early Activation Antigen

Gene Symbols:
CD69

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CD69

Clone:
FN50

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q07108

Gene ID (Entrez):
969

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody