7162177

CD62P (P-Selectin) Monoclonal Antibody (Psel.KO2.3), Super Bright™ 600, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD62P (P-Selectin)

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias

CD62, CD62 antigen-like family member P, CD62P, CD62P antigen, CD62P, CD62 homolog, FLJ45155, GMP140, GMP-140, GMRP, Granule membrane protein 140, granule membrane protein 140kDa, granulocyte membrane protein, Grmp, LECAM3, leukocyte-endothelial cell adhesion molecule 3, PADGEM, Platelet activation dependent granule-external membrane protein, platelet alpha-granule membrane protein, PSEL, PSELECT, P-selectin, P-selectin precursor, RP1-86F14.2, selectin P, selectin P (granule membrane protein 140kDa, antigen CD62), selectin, platelet, Selp

Gene Symbols

SELP

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

SELP

Clone

Psel.KO2.3

Applications

Flow Cytometry

Conjugate

Super Bright 600

Host Species

Mouse

Target Species

Human, Mouse

Gene Accession No.

P16109, Q01102

Gene ID (Entrez)

20344, 6403

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Product Type

Antibody

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Description

  • Description: The Psel.KO2.3 monoclonal antibody reacts with mouse CD62P (also known as P-selectin and GMP-140), a 140-kDa cell adhesion molecule that can be induced on endothelial cells and platelets
  • During inflammation, this selectin mediates adhesion of monocytes and neutrophils to activated platelets, as well as leukocyte rolling on endothelial cells
  • The major ligand for CD62P on neutrophils is P-selectin glycoprotein ligand-1 (PSGL-1)
  • This monoclonal antibody recognizes an epitope that is conserved across several species (e.g
  • mouse, human, and rat) and has not been reported to block cell adhesion
  • Applications Reported: This Psel.KO2.3 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This Psel.KO2.3 antibody has been tested by flow cytometric analysis of thrombin-activated platelets
  • This may be used at less than or equal to 0.5 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Super Bright 600 is a tandem dye that can be excited with the violet laser line (405 nm) and emits at 600 nm
  • We recommend using a 610/20 bandpass filter
  • Please make sure that your instrument is capable of detecting this fluorochrome
  • P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling
  • P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets
  • From there, it can be rapidly brought to the cell surface after exposure to thrombin, histamine, complement 5a, Ca21 ionophores, or adenosine diphosphate
  • P-selectin protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes
  • P-selectin plays an important role in adhesive processes between leucocytes and endothelial cells, and is a calcium dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens found on neutrophils and monocytes
  • P-selectin is constitutively expressed in inflammation and contributes to atherogenesis, thrombosis and tissue destruction
  • Clinically, P-selectin is used to distinguish heparin induced thrombocytopenia with and without thrombosis.

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7162177

Mouse Monoclonal Antibody...


Antigen:
CD62P (P-Selectin)

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
CD62, CD62 antigen-like family member P, CD62P, CD62P antigen, CD62P, CD62 homolog, FLJ45155, GMP140, GMP-140, GMRP, Granule membrane protein 140, granule membrane protein 140kDa, granulocyte membrane protein, Grmp, LECAM3, leukocyte-endothelial cell adhesion molecule 3, PADGEM, Platelet activation dependent granule-external membrane protein, platelet alpha-granule membrane protein, PSEL, PSELECT, P-selectin, P-selectin precursor, RP1-86F14.2, selectin P, selectin P (granule membrane protein 140kDa, antigen CD62), selectin, platelet, Selp

Gene Symbols:
SELP

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
SELP

Clone:
Psel.KO2.3

Applications:
Flow Cytometry

Conjugate:
Super Bright 600

Host Species:
Mouse

Target Species:
Human, Mouse

Gene Accession No.:
P16109, Q01102

Gene ID (Entrez):
20344, 6403

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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7162190

Mouse Monoclonal Antibody...


Antigen:
CD8a

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
BB154331, CD8, CD8 alpha, CD8 alpha chain, CD8 alpha chain precursor, CD8 antigen, CD8 antigen 32 kDa chain, CD8 antigen 37 kDa chain, CD8 antigen alpha polypeptide, CD8 antigen alpha protein, CD8 antigen alpha protein precursor, CD8 antigen alpha-chain, CD8 antigen beta polypeptide, CD8 antigen beta polypeptide precursor, CD8 antigen beta-chain, CD8 antigen, alpha chain, CD8 antigen, alpha polypeptide, CD8 antigen, alpha polypeptide (p32), CD8 antigen, alpha-chain, CD8 antigen, beta chain, CD8 antigen, beta chain 1, CD8 antigen, beta polypeptide, CD8 antigen, beta polypeptide 1 (p37), CD8 antigen, beta-chain, CD8 beta, CD8 beta chain, CD8 beta-2, CD8a, CD8A antigen alpha, CD8a molecule, CD8A, T-cell surface glycoprotein, CD8alpha, CD8B, CD8b antigen, CD8b molecule, CD8b molecule pseudogene, Cd8b1, CD8beta, CD8BP, fCD8, LEU2, Leu-2, Leu2 T-lymphocyte antigen, leu-2a, Ly-2, LY3, Ly-3, Ly-35, Ly-B, Ly-C, Lymphocyte antigen 3, Lyt2, Lyt-2, Lyt-2.1 lymphocyte differentiation antigen (AA at 100), Lyt3, Lyt-3, MAL, membrane glycoprotein, membrane protein, OKT8 T-cell antigen, OX-8 membrane antigen, p32, P37, RHACD8-4, T cell co-receptor, T lymphocyte surface glycoprotein beta chain, T8 T-cell antigen, T-cell antigen Leu2, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 beta chain, T-cell surface glycoprotein Lyt-2, T-cell surface glycoprotein Lyt-3, T-cell surface molecule, T-lymphocyte differentiation antigen T8/Leu-2, type I transmembrane glycoprotein

Gene Symbols:
Cd8a, CD8B

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CD8B

Clone:
HIT8a

Applications:
Flow Cytometry

Conjugate:
Super Bright 600

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P01732, P10966

Gene ID (Entrez):
925, 926

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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7162214

Mouse Monoclonal Antibody...


Antigen:
HLA-DR

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
AI323765, BLA-DRB3, BOLA-DRA, BoLA-DR-alpha, BoLA-DRB, BOLA-DRB3, BoLA-DRB3 protein, BoLA-DRB3.2, Bota-DRB01, Bota-DRB02, Bota-DRB04, Bota-DRB07, Bota-DRB21, Bota-DRB22, bovine leukocyte antigen, Cd74, CD74 antigen, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated), CD74 molecule, Cd74 molecule, major histocompatibility complex, class II invariant chain, class II-associated invariant chain peptide, CLIP, Clone P2-beta-3, DASS-397D15.1, DHLAG, dinucleotide microsatellite, DLA class II histocompatibility antigen, DR-1 beta chain, DLA DRBB1 beta chain, DLA-DR beta, DLA-DRB1, DLA-DRBB1, DR beta-5, DR beta-chain antigen binding domain, DR-16, DR2-beta-2, DR4, DR-4, DR7, DR9, DR-9, DRB, DRB1, DRB1 transplantation antigen, DRB3, DRB4, DRBB1, DR-beta chain, DR-beta chain MHC class II, DRw10, Dw2, DW2.2/DR2.2, E-alpha-f, FLJ51114, FLJ75017, FLJ76359, gamma chain of class II antigens, H-2 class II histocompatibility antigen gamma chain, H-2 cla

Gene Symbols:
CD74, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
HLA-DRB4

Clone:
L243

Applications:
Flow Cytometry

Conjugate:
PE-eFluor 610

Host Species:
Mouse

Target Species:
Canine, Cynomolgus Monkey, Human, Non-human Primate, Rhesus Monkey

Gene Accession No.:
P01903, P01911, P04233, P13762, P18470, P79483, Q30154

Gene ID (Entrez):
102131412, 3122, 3123, 3125, 3126, 3127, 474860, 479329, 710820, 972

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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7162215

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Antigen:
IL-2

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
aldesleukin, cytokine, H-IL-2, il 2, Il2, Il-2, ILN, Interleukin, interleukin 2, interleukin 2 precursor, interleukin 2 variant IL2delta2, Interleukin2, Interleukin-2, interleukin-2 precursor, interleukin-2 precursor protein, interleukin-2, interleukin 2, Involved in regulation of T cell clonal expansion, involved in regulation of T-cell clonal expansion, lymphokine, M-IL-2, patial sequence of Interleukin-2, POIL2, porcine Interleukin 2, T cell growth factor, T-cell growth factor, T-cell growth factor (TCGF), TCGF

Gene Symbols:
IL2

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
IL2

Clone:
MQ1-17H12

Applications:
Flow Cytometry

Conjugate:
Alexa Fluor 532

Host Species:
Rat

Target Species:
Human

Gene Accession No.:
P60568

Gene ID (Entrez):
3558

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody