7090431

EOMES Monoclonal Antibody (Dan11mag), PE-Cyanine7, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

EOMES

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Alias

C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2

Gene Symbols

Eomes

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

Eomes

Clone

Dan11mag

Applications

Flow Cytometry

Conjugate

PE-Cyanine7

Host Species

Rat

Target Species

Mouse

Gene Accession No.

O54839

Gene ID (Entrez)

13813

Isotype

IgG2a κ

Purification Method

Affinity chromatography

Product Type

Antibody

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Description

  • Description: This Dan11mag antibody recognizes Eomesodermin (EOMES), also known as T-box brain 2 (TBR2)
  • Eomes is a T-box transcription factor that is highly homologous to T-bet, which is essential during trophoblast development and gastrulation in most vertebrates
  • In the immune system, Eomes controls the differentiation of effector and memory CD8+ T cells, as well as natural killer (NK) cells
  • Expression of Eomes in these cells correlates with high expression of CD122, the common beta-chain of the IL-2R and IL-15R
  • Applications Reported: This Dan11mag antibody has been reported for use in intracellular staining followed by flow cytometric analysis
  • Applications Tested: This Dan11mag antibody has been tested by intracellular staining and flow cytometric analysis of mouse splenocytes using the Foxp3/Transcription Factor Buffer Set (cat 00-5523) and protocol
  • Please see Best Protocols Section (Staining intracellular Antigens for Flow Cytometry) for staining protocol (refer to Protocol B: One-step protocol for intracellular (nuclear) proteins)
  • This can be used at less than or equal to 0.25 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box
  • T-box genes encode transcription factors involved in the regulation of developmental processes
  • A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation
  • TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.

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Antigen:
EOMES

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2

Gene Symbols:
Eomes

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Eomes

Clone:
Dan11mag

Applications:
Flow Cytometry

Conjugate:
PE-Cyanine7

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
O54839

Gene ID (Entrez):
13813

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
EOMES

Concentration:
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Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
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Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2

Gene Symbols:
Eomes

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Eomes

Clone:
WD1928

Applications:
Flow Cytometry

Conjugate:
PE-Cyanine7

Host Species:
Mouse

Target Species:
Human, Porcine

Gene Accession No.:
O95936

Gene ID (Entrez):
100622125, 8320

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IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Concentration:
0.2 mg/mL

Classification:
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Form:
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Regulatory Status:
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Formulation:
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Gene Alias:
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Gene Symbols:
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Primary or Secondary:
Isotype Control (Primary)

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
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Clone:
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Applications:
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Conjugate:
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Host Species:
Armenian Hamster

Target Species:
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Gene Accession No.:
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Gene ID (Entrez):
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Classification:
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Form:
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Regulatory Status:
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Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
Abeta; AI323765; AI845868; cell surface glycoprotein; E-alpha-f; H-2 class II histocompatibility antigen, A beta chain; H-2 class II histocompatibility antigen, E-D alpha chain; H-2 class II histocompatibility antigen, E-K alpha chain; H-2 class II histocompatibility antigen, E-U alpha chain; H-2 class II histocompatibility antigen, I-E beta chain; H-2Ab; H2-Ab; H2-Ab1; H-2Ea; H2-Ea; H2-Ea-ps; H2Eb; H-2Eb; H2-Eb1; H2-iabeta; H2-IE-alpha; histocompatibility 2, class II antigen A, beta 1; histocompatibility 2, class II antigen E alpha; histocompatibility 2, class II antigen E alpha, pseudogene; histocompatibility 2, class II antigen E beta; Ia2; Ia-2; Ia3; Ia-3; Ia4; Ia-4; IAb; I-Ab; I-Abeta; I-Ad; I-Aq; I-E alpha MHC class II; I-E beta MHC class II; I-Ealpha; I-Ed; I-Ek; major histocompatibility complex class II beta chain; major histocompatibility complex H-2E beta chain; MHC class 2; MHC class II antigen A beta; MHC class II antigen E alpha; MHC class II H2-IA-beta-psi; MHC class II IE-b; MHC class II protein; MHC H2-IE-beta cell surface glycoprotein; response to metastatic cancers 1; Rmcs1

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H2-Ab1, H2-Eb1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
H2-Ab1

Clone:
M5/114.15.2

Applications:
Flow Cytometry

Conjugate:
PE-Cyanine7

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P01921, P04230, P06342, P06343, P06344, P06345, P06346, P14483

Gene ID (Entrez):
14961, 14969

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Product Type:
Antibody