7092397

CD117 Mouse anti-Human, PE, Clone: YB5.B8, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD117

Concentration

0.2mg/mL

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

Acute myelocytic leukemia blasts

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

YB5.B8

Applications

Flow Cytometry

Conjugate

PE

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

KIT; c-Kit; SCFR; PBT; Mast/stem cell growth factor receptor

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Description

  • The YB5.B8 monoclonal antibody specifically binds to CD117
  • CD117, also known as c-Kit, is a 145 kDa cell-surface glycoprotein with tyrosine kinase activity
  • CD117 is present on hematopoietic progenitor cell subsets, thymocytes, mast cells, hepatocytes and histiocytes
  • CD117 serves as a cytokine receptor for steel factor (SLF), also known as stem cell factor (SCF) or mast cell growth factor (MGF)
  • The interaction of c-Kit and SLF is crucial to hematopoiesis, mast cell differentiation, melanogenesis, and germ cell development
  • The ability of the YB5.B8 antibody to block the binding of c-Kit ligand is still controversial.

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Img

Fischer Scientific

7092397

Mouse Monoclonal Antibody...


Antigen:
CD117

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Acute myelocytic leukemia blasts

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
YB5.B8

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
KIT; c-Kit; SCFR; PBT; Mast/stem cell growth factor receptor

Img

Fischer Scientific

7092398

Rat Monoclonal Antibody...


Antigen:
CD117

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
Mouse Bone Marrow Mast Cells

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
2B8

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

Description:
c-KIT; W; SCFR; Stem Cell Factor Receptor; Sl; Steel Factor Receptor; Ssm

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7092401

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Antigen:
CD11b

Concentration:
0.5mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Human, Mouse

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
M1/70

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

Description:
Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain

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7092402

Rat Monoclonal Antibody...


Antigen:
CD11b

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
Mouse Splenic Cells

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
M1/70

Applications:
Flow Cytometry

Conjugate:
PE-CF594

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

Description:
Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain