7092407

CD123 Mouse anti-Human, PE, Clone: 7G3, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD123

Concentration

0.2mg/mL

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

Human IL-3Ra-transfected cells

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

7G3

Applications

Flow Cytometry

Conjugate

PE

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Isotype

IgG2a κ

Purification Method

Affinity Purified

Description

IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha

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Description

  • The 7G3 monoclonal antibody specifically reacts with human CD123, the 70 kDa IL-3 Receptor α (IL-3Rα) chain
  • CD123 associates with CD131, the 120-140 kDa Common β chain to form the IL-3 Receptor Complex
  • CD131 is shared with the receptors for interleukins IL-5 and GM-CSF
  • IL-3Rα is expressed on hematopoietic progenitors and plays an important role in hematopoietic progenitor cell growth and differentiation
  • It is also expressed by mast cells, macrophages and a CD5+ B cell subset
  • This antibody has been reported to block the binding of 125I-IL-3 to high and low affinity IL-3 receptors
  • In functional experiments, this antibody was found to inhibit acute myeloid leukemia cell proliferation, basophil histamine release, endothelial cell-mediated IL-8 secretion, and neutrophil transmigration
  • This antibody has been reported to be useful for immunoprecipitation, Western blot and immunofluorescent staining for flow cytometry
  • At the Fifth HLDA Workshop, the human IL-3 receptor was designated CD123.

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Fischer Scientific

7092407

Mouse Monoclonal Antibody...


Antigen:
CD123

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human IL-3Ra-transfected cells

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
7G3

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha

Img

Fischer Scientific

7092408

Mouse Monoclonal Antibody...


Antigen:
CD126

Concentration:
__

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
M5

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
Interleukin 6 Receptor alpha chain; IL-6R alpha; IL-6Rα

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Mouse Monoclonal Antibody...


Antigen:
CD127

Concentration:
__

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human IL-7R Recombinant Protein

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
HIL-7R-M21

Applications:
Flow Cytometry

Conjugate:
Alexa Fluor 647

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
IL-7R; IL7R; IL7RA; IL-7Rα; IL-7R-alpha; Interleukin-7 Receptor alpha

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7092410

Mouse Monoclonal Antibody...


Antigen:
CD127

Concentration:
__

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human IL-7R Recombinant Protein

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
HIL-7R-M21

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
IL-7R; IL7R; IL7RA; IL-7Rα; IL-7R-alpha; Interleukin-7 Receptor alpha