7092411

CD127 Mouse anti-Human, PE, Clone: HIL-7R-M21, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD127

Concentration

0.2mg/mL

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

Human IL-7R Recombinant Protein

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

HIL-7R-M21

Applications

Flow Cytometry

Conjugate

PE

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

IL-7R; IL7R; IL7RA; IL-7Rα; IL-7R-alpha; Interleukin-7 Receptor alpha

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Description

  • The hIL-7R-M21 monoclonal antibody specifically binds to the 60-90 kDa glycoprotein, CD127
  • CD127 is also known as the IL-7 receptor alpha (IL-7Rα) subunit
  • The IL-7 receptor complex is a heterodimer composed of CD127 and the common gamma chain (γc, CD132), shared by other cytokine receptors (IL-2R, IL-4R, IL-9R, IL-15R, and IL-21R)
  • CD127 is expressed on thymocytes, T- and B-cell progenitors, mature T cells, and some lymphoid and myeloid cells
  • In vitro experiments show the expression of CD127 is down-regulated following T cell activation
  • Studies indicate that the IL-7 Receptor plays an important role in the proliferation and differentiation of mature T cells
  • Recently, it has been shown that low surface expression of CD127, in combination with intermediate to high surface expression of CD25, the α chain of the IL-2 receptor complex, can distinguish between human regulatory and conventional CD4+ T cells in human adult and cord blood, lymph nodes and thymus.

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Fischer Scientific

7092411

Mouse Monoclonal Antibody...


Antigen:
CD127

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human IL-7R Recombinant Protein

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
HIL-7R-M21

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
IL-7R; IL7R; IL7RA; IL-7Rα; IL-7R-alpha; Interleukin-7 Receptor alpha

Img

Fischer Scientific

7092413

Mouse Monoclonal Antibody...


Antigen:
CD13

Concentration:
__

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human AML Cells

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
WM15

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
__

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7092414

Mouse Monoclonal Antibody...


Antigen:
CD132

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
AG184

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
IL2RG; IL-2RG; IL-2Rγ; Common gamma chain; γc; CIDX; SCIDX; SCIDX1; IMD4

Img

Fischer Scientific

7092414

Mouse Monoclonal Antibody...


Antigen:
CD132

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
AG184

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
IL2RG; IL-2RG; IL-2Rγ; Common gamma chain; γc; CIDX; SCIDX; SCIDX1; IMD4