7092785

Nanog Mouse anti-Human, PE, Clone: N31-355, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Nanog

Applications

Flow Cytometry

Conjugate

PE

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Clone

N31-355

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

Human Nanog Recombinant Protein

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • Description The N31-355 monoclonal antibody reacts with human Nanog (named for Tir Na Nog, the land of the ever-young of Celtic mythology), which is a homeobox transcription factor required for the maintenance of the undifferentiated state of pluripotent stem cells
  • Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF (Leukemia Inhibitory Factor) and BMP (Bone Morphogenic Protein)
  • When Nanog expression is down-regulated, cell differentiation can proceed
  • Proteins that regulate Nanog expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53
  • Nanog is one of the factors that can contribute to reprogramming of differentiated cells to an induced pluripotent stem cell state.

Compare Similar Items

Show Difference

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Fischer Scientific

7092785

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Antigen:
Nanog

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Clone:
N31-355

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human Nanog Recombinant Protein

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
NK-1.1

Applications:
Flow Cytometry

Conjugate:
APC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Clone:
PK136

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Mouse

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
NK-1.1

Applications:
Flow Cytometry

Conjugate:
PE-Cyanine7

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Clone:
PK136

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Mouse

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
NKG2D

Applications:
Flow Cytometry

Conjugate:
APC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Clone:
1D11

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
NKL cells

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.