7092791
NKG2D Mouse anti-Human, APC, Clone: 1D11, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
NKG2D
Applications
Flow Cytometry
Conjugate
APC
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype
IgG1 κ
Purification Method
Affinity Purified
Clone
1D11
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Immunogen
NKL cells
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The 1D11 monoclonal antibody specifically binds to NKG2D, a 42 kDa type II transmembrane glycoprotein that is also known as CD314 and KLRK1
- NKG2D is a member of the C-type lectin family and is expressed on human NK cells
- This activating receptor binds strongly to several ligands including MICA and MICB and ULBP-1, -2, and -3 proteins that are expressed by different target cell types
- Different from natural cytotoxicity receptor (NCR), NKG2D expression is not confined to NK cells
- It is also expressed on virtually all TCR γ/δ+ and CD8+TCR α/β+ T cells
- NKG2D functions as a triggering receptor involved in natural cytotoxicity mediated by normal NK cells against a variety of tumors or normal target cells
- Importantly, NKG2D can complement the role of NCR in tumor cell lysis
- Remarkably, the combined maskings of NCR and NKG2D can reportedly lead to a complete inhibition of NK-mediated lysis of all tumor or normal cells
- The 1D11 antibody can reportedly block or stimulate the function of NKG2D-positive cells.
Compare Similar Items
Show Difference
Antigen: NKG2D
Applications: Flow Cytometry
Conjugate: APC
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Clone: 1D11
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: NKL cells
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
NKG2D
Applications:
Flow Cytometry
Conjugate:
APC
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Clone:
1D11
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
NKL cells
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Siglec-F
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Clone: E50-2440
Classification: Monoclonal
Host Species: Rat
Target Species: Mouse
Immunogen: Mouse Siglec-F and human IgG Fc recombinant fusion protein
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Siglec-F
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Clone:
E50-2440
Classification:
Monoclonal
Host Species:
Rat
Target Species:
Mouse
Immunogen:
Mouse Siglec-F and human IgG Fc recombinant fusion protein
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: SSEA-1
Applications: Flow Cytometry
Conjugate: Alexa Fluor 647
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype: IgM κ
Purification Method: Affinity Purified
Clone: MC480
Classification: Monoclonal
Host Species: Mouse
Target Species: Human, Mouse
Immunogen: __
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
SSEA-1
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor 647
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype:
IgM κ
Purification Method:
Affinity Purified
Clone:
MC480
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human, Mouse
Immunogen:
__
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: SSEA-1
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype: IgM κ
Purification Method: Affinity Purified
Clone: MC480
Classification: Monoclonal
Host Species: Mouse
Target Species: Human, Mouse
Immunogen: Mouse Teratocarcinoma Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
SSEA-1
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype:
IgM κ
Purification Method:
Affinity Purified
Clone:
MC480
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human, Mouse
Immunogen:
Mouse Teratocarcinoma Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.