7092568
CD40 Mouse anti-Human, APC, Clone: 5C3, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD40
Applications
Flow Cytometry
Conjugate
APC
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone
5C3
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Isotype
IgG1 κ
Purification Method
Affinity Purified
Related Products
Description
- This 5C3 monoclonal antibody specifically binds to CD40, a 45-48 kDa type I integral membrane glycoprotein
- CD40 is expressed on B lymphocytes, but is not expressed on terminally differentiated B cells
- CD40 is also expressed by endothelial cells, basal epithelial cells and some epithelial cell carcinomas, follicular dendritic cells, macrophages, fibroblasts, keratinocytes, and CD34+ hematopoietic progenitor cells
- This antibody is useful for studying the roles played by CD40 in B-cell growth, proliferation, and differentiation including immunoglobulin isotype switching
- Anti-CD40 antibodies have been reported to stimulate B-cell proliferation when costimulated with anti-µ, anti-CD20 antibodies or with phorbol esters
- 5C3 is capable of inducing B-cell proliferation when presented with IL-4
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Compare Similar Items
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Antigen: CD40
Applications: Flow Cytometry
Conjugate: APC
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: 5C3
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Isotype: IgG1 κ
Purification Method: Affinity Purified
Antigen:
CD40
Applications:
Flow Cytometry
Conjugate:
APC
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
5C3
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Antigen: CD40
Applications: Flow Cytometry
Conjugate: FITC
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: 3/23
Classification: Monoclonal
Host Species: Rat
Target Species: Mouse
Isotype: IgG2a κ
Purification Method: Affinity Purified
Antigen:
CD40
Applications:
Flow Cytometry
Conjugate:
FITC
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
3/23
Classification:
Monoclonal
Host Species:
Rat
Target Species:
Mouse
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Antigen: CD40
Applications: Flow Cytometry
Conjugate: FITC
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: 3/23
Classification: Monoclonal
Host Species: Rat
Target Species: Mouse
Isotype: IgG2a κ
Purification Method: Affinity Purified
Antigen:
CD40
Applications:
Flow Cytometry
Conjugate:
FITC
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
3/23
Classification:
Monoclonal
Host Species:
Rat
Target Species:
Mouse
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Antigen: CD40
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: 3/23
Classification: Monoclonal
Host Species: Rat
Target Species: Mouse
Isotype: IgG2a κ
Purification Method: Affinity Purified
Antigen:
CD40
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
3/23
Classification:
Monoclonal
Host Species:
Rat
Target Species:
Mouse
Isotype:
IgG2a κ
Purification Method:
Affinity Purified