7092557

CD4 Mouse anti-Human, PE, Clone: RPA-T4, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD4

Applications

Flow Cytometry

Conjugate

PE

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

RPA-T4

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Isotype

IgG1 κ

Purification Method

Affinity Purified

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Description

  • The RPA-T4 monoclonal antibody specifically binds to CD4, a 59 kDa single-chain transmembrane glycoprotein that is expressed on T-helper/inducer cell populations
  • CD4 is also expressed on thymocytes subsets and at lower levels on monocytes and macrophages
  • CD4 functions as a co-receptor in MHC class II-restricted antigen-induced T cell activation and as a receptor for human immunodeficiency viruses (HIV)
  • This antibody binds to the D1 domain (CDR1 and CDR3 epitopes) of the CD4 antigen and reacts with approximately 80% of thymocytes and 45% of peripheral blood lymphocytes
  • RPA-T4 is capable of blocking HIV-1, gp120, and inhibits syncytium formation
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development or are reported in the literature.

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Show Difference

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Antigen:
CD4

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
RPA-T4

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

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Rat Monoclonal Antibody...


Antigen:
CD4

Applications:
Flow Cytometry

Conjugate:
Alexa Fluor 700

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
RM4-5

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

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Antigen:
CD4

Applications:
Flow Cytometry

Conjugate:
APC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
RM4-5

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

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Antigen:
CD4

Applications:
Flow Cytometry

Conjugate:
APC-Cyanine7

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
GK1.5

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Isotype:
IgG2b κ

Purification Method:
Affinity Purified