7092570

CD40 Rat anti-Mouse, PE, Clone: 3/23, BD

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD40

Concentration

0.2mg/mL

Classification

Monoclonal

Host Species

Rat

Target Species

Mouse

Immunogen

Mouse CD40 Recombinant Protein

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

3/23

Applications

Flow Cytometry

Conjugate

PE

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype

IgG2a κ

Purification Method

Affinity Purified

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Description

  • The 3/23 clone monoclonal antibody specifically binds to CD40, a 40-50 kDa glycoprotein expressed on B lymphocytes and other antigen-presenting cells
  • CD40 has been reported to be transiently expressed on activated CD4+ and CD8+ T cells and in some mouse strains, the 3/23 mAb has been reported to react with 5-10% of T lymphocytes in adult mouse, but not neonatal, spleen
  • CD40 plays a key role in B-cell growth and differentiation where interactions of CD40 with its ligand, CD154, are involved in the initiation, effector, and memory stages of cell-mediated immune responses
  • In addition, CD40 has been reported to be involved with the triggering of NK cells and NK-T cells
  • Ligation of CD40 with the 3/23 antibody has been reported to induce splenic B cells to express the costimulatory molecule CD86 (B7-2)
  • In addition, although the 3/23 antibody by itself is a weak B-cell mitogen, it has been reported to synergize markedly with mitogenic anti-IgM, anti-IgD mAb or IL-4 to promote B-cell proliferation.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7092570

Rat Monoclonal Antibody...


Antigen:
CD40

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
Mouse CD40 Recombinant Protein

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
3/23

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

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Fischer Scientific

7092571

Rat Monoclonal Antibody...


Antigen:
CD41

Concentration:
0.5mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
Mouse Platelets

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
MWREG30

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

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7092573

Mouse Monoclonal Antibody...


Antigen:
CD41a

Concentration:
__

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Purified platelet membrane glycoproteins

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
HIP8

Applications:
Flow Cytometry

Conjugate:
APC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

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Fischer Scientific

7092573

Mouse Monoclonal Antibody...


Antigen:
CD41a

Concentration:
__

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Purified platelet membrane glycoproteins

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
HIP8

Applications:
Flow Cytometry

Conjugate:
APC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified