7092793
Siglec-F Rat anti-Mouse, PE, Clone: E50-2440, BD
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Siglec-F
Concentration
0.2mg/mL
Classification
Monoclonal
Host Species
Rat
Target Species
Mouse
Immunogen
Mouse Siglec-F and human IgG Fc recombinant fusion protein
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone
E50-2440
Applications
Flow Cytometry
Conjugate
PE
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype
IgG2a κ
Purification Method
Affinity Purified
Related Products
Description
- The E50-2440 antibody reacts with Siglec-F, the sixth siglec protein to be reported in the mouse
- Siglecs are the s ialic acid-binding immunoglobulin superfamily lectins defined in the human, each of which has a distinctive expression pattern in the hematopoietic system and at least some of which are known to mediate cell-cell interactions
- Orthologous proteins of human Siglec-1 (Sialoadhesin or CD169), Siglec-2 (CD22), and Siglec-4 (myelin-associated glycoprotein) have been characterized in the mouse
- Human Siglec-3 (CD33) and Siglecs-5 through -10 are encoded by a cluster of closely related genes, and each has two cytoplasmic ITIM (Immunoreceptor Tyrosine-based Inhibitory Motifs)
- Similarly, mouse Siglec-F is encoded by a gene in a syntenic cluster in the mouse, and the protein has sialic acid-binding activity and an intracytoplasmic ITIM
- Its expression pattern differs from those of the human Siglec-3-related proteins in that it is found on immature cells of the myelomonocytic lineage, with reduced expression on mature neutrophils and monocytes, and not on lymphoid cells
- It has been proposed that mAb E50-2440 may be used for identification of immature myelomonocytic cells in the mouse.
Compare Similar Items
Show Difference
Antigen: Siglec-F
Concentration: 0.2mg/mL
Classification: Monoclonal
Host Species: Rat
Target Species: Mouse
Immunogen: Mouse Siglec-F and human IgG Fc recombinant fusion protein
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: E50-2440
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Antigen:
Siglec-F
Concentration:
0.2mg/mL
Classification:
Monoclonal
Host Species:
Rat
Target Species:
Mouse
Immunogen:
Mouse Siglec-F and human IgG Fc recombinant fusion protein
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
E50-2440
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Antigen: SSEA-1
Concentration: __
Classification: Monoclonal
Host Species: Mouse
Target Species: Human, Mouse
Immunogen: __
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: MC480
Applications: Flow Cytometry
Conjugate: Alexa Fluor 647
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype: IgM κ
Purification Method: Affinity Purified
Antigen:
SSEA-1
Concentration:
__
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human, Mouse
Immunogen:
__
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
MC480
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor 647
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype:
IgM κ
Purification Method:
Affinity Purified
Antigen: SSEA-1
Concentration: __
Classification: Monoclonal
Host Species: Mouse
Target Species: Human, Mouse
Immunogen: Mouse Teratocarcinoma Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: MC480
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype: IgM κ
Purification Method: Affinity Purified
Antigen:
SSEA-1
Concentration:
__
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human, Mouse
Immunogen:
Mouse Teratocarcinoma Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
MC480
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype:
IgM κ
Purification Method:
Affinity Purified
Antigen: SSEA-1
Concentration: __
Classification: Monoclonal
Host Species: Mouse
Target Species: Human, Mouse
Immunogen: Mouse Teratocarcinoma Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: MC480
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype: IgM κ
Purification Method: Affinity Purified
Antigen:
SSEA-1
Concentration:
__
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human, Mouse
Immunogen:
Mouse Teratocarcinoma Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
MC480
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype:
IgM κ
Purification Method:
Affinity Purified