7092455
CD195 Mouse anti-Human, PE-Cy5, Clone: 2D7/CCR5, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD195
Applications
Flow Cytometry
Conjugate
PE-Cyanine5
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype
IgG2a κ
Purification Method
Affinity Purified
Description
CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Clone
2D7/CCR5
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Immunogen
Human CCR5 Transfected Cell Line
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The 2D7/CCR5 monoclonal antibody specifically binds to the human chemokine receptor, CCR5
- CCR5 is also known as CD195
- CCR5 is a seven transmembrane-spanning G protein-associated molecule
- CCR5 belongs to the beta chemokine receptor family
- It is expressed on a subset of T lymphocytes (CD3+CD45RO+CD95+)
- CCR5 regulates lymphocyte chemotaxis activation and transendothelial migration during inflammation
- It signals a response to at least three chemokines: Regulated upon Activation Normal T-cell Expressed and Secreted (RANTES), Macrophage Inflammatory Protein-1 (MIP-1) and Monocyte Chemoattractant Protein 2 (MCP-2)
- Additionally, CCR5 has been found to be a coreceptor for macrophage-tropic HIV-1 on CD4+ cells, a characteristic that is important in viral transmission
- Reports indicate that individuals who have partial (heterozygous) or complete (homozygous) deletion of the CCR5 allele, demonstrate resistance to HIV infection
- This antibody has been shown to block ligand and gp120 binding
- It is also able to neutralize HIV infection.
Compare Similar Items
Show Difference
Antigen: CD195
Applications: Flow Cytometry
Conjugate: PE-Cyanine5
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Description: CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Clone: 2D7/CCR5
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Human CCR5 Transfected Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD195
Applications:
Flow Cytometry
Conjugate:
PE-Cyanine5
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Description:
CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Clone:
2D7/CCR5
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Human CCR5 Transfected Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD195
Applications: Flow Cytometry
Conjugate: PE-Cyanine7
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Description: CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Clone: 2D7/CCR5
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Human CCR5 Transfected Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD195
Applications:
Flow Cytometry
Conjugate:
PE-Cyanine7
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Description:
CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Clone:
2D7/CCR5
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Human CCR5 Transfected Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD1a
Applications: Flow Cytometry
Conjugate: APC
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: __
Clone: HI149
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: __
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD1a
Applications:
Flow Cytometry
Conjugate:
APC
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
__
Clone:
HI149
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
__
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD1a
Applications: Flow Cytometry
Conjugate: FITC
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: __
Clone: HI149
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: __
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD1a
Applications:
Flow Cytometry
Conjugate:
FITC
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
__
Clone:
HI149
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
__
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.