7092515

CD28 Mouse anti-Human, FITC, Clone: CD28.2, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD28

Applications

Flow Cytometry

Conjugate

FITC

Regulatory Status

RUO

Target Species

Human

Immunogen

Human CD28 Transfected Cell Line

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

CD28.2

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Immunology

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

CD28 antigen; T44; Tp44; TP44

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Description

  • The CD28.2 monoclonal antibody specifically binds to CD28, a 44 kDa homodimeric transmembrane glycoprotein present on most mature T cells, thymocytes and plasma cells
  • CD28 is a costimulatory receptor that binds CD80 and CD86 as ligands and plays a very important role in T cell-B cell interactions
  • It has been suggested that CD28 initiates and regulates a separate and distinct signal transduction pathway from those stimulated by the TCR complex
  • Additionally, it has been reported that CD28 antibody clones vary in their ability to stimulate T cells to produce IL-2 and increase intracellular Ca2+ concentration
  • This finding suggests the existence of functionally distinct subregions on the CD28 molecule
  • CD28.2 has been demonstrated to bind to the same molecule as clone L293, another CD28 mAb, and has been reported to induce Ca2+ influx in Jurkat T cells.

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7092515

Mouse Monoclonal Antibody...


Antigen:
CD28

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Target Species:
Human

Immunogen:
Human CD28 Transfected Cell Line

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
CD28.2

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Immunology

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
CD28 antigen; T44; Tp44; TP44

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Rat Monoclonal Antibody...


Antigen:
CD3 Molecular Complex

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Target Species:
Mouse

Immunogen:
γδ TCR-positive T-T hybridoma D1

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
17A2

Classification:
Monoclonal

Host Species:
Rat

Research Discipline:
Immunology

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

Description:
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Rat Monoclonal Antibody...


Antigen:
CD3 Molecular Complex

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Target Species:
Mouse

Immunogen:
γδ TCR-positive T-T hybridoma D1

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
17A2

Classification:
Monoclonal

Host Species:
Rat

Research Discipline:
Immunology

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

Description:
__

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Rat Monoclonal Antibody...


Antigen:
CD3 Molecular Complex

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Target Species:
Mouse

Immunogen:
γδ TCR-positive T-T hybridoma D1

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
17A2

Classification:
Monoclonal

Host Species:
Rat

Research Discipline:
Immunology

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

Description:
__