7092536

CD31 Rat anti-Mouse, PE, Clone: MEC 13.3, BD

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD31

Concentration

0.2mg/mL

Classification

Monoclonal

Host Species

Rat

Target Species

Mouse

Immunogen

129/Sv mouse-derived endothelioma cell line tEnd.1

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

MEC 13.3

Applications

Flow Cytometry

Conjugate

PE

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype

IgG2a κ

Purification Method

Affinity Purified

Description

PECAM-1

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Description

  • The MEC13.3 antibody reacts with CD31, also known as PECAM-1 (Platelet Endothelial Cell Adhesion Molecule-1)
  • CD31 is a 130 kDa integral membrane protein, a member of the immunoglobulin superfamily, that mediates cell-to-cell adhesion
  • CD31 is expressed constitutively on the surface of adult and embryonic endothelial cells and is also expressed on many peripheral leukocytes and platelets
  • It has also been detected on bone marrow-derived hematopoietic stem cells and embryonic stem cells
  • CD31 is involved in the transendothelial emigration of neutrophils, and neutrophil PECAM-1 appears to be down-regulated after extravasation into inflamed tissues
  • Multiple alternatively spliced isoforms are detected during early post-implantation embryonic development; this alternative splicing is involved in the regulation of ligand specificity
  • CD38 and vitronectin receptor (αvβ3 integrin, CD51/CD61) are proposed to be ligands for CD31
  • CD31-mediated endothelial cell-cell interactions are involved in angiogenesis
  • The MEC13.3 mAb inhibits a variety of in vitro and in vivo functions mediated by CD31.

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Show Difference

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7092536

Rat Monoclonal Antibody...


Antigen:
CD31

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
129/Sv mouse-derived endothelioma cell line tEnd.1

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
MEC 13.3

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
PECAM-1

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Rat Monoclonal Antibody...


Antigen:
CD31

Concentration:
0.5mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
129/Sv mouse-derived endothelioma cell line tEnd.1

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Clone:
MEC 13.3

Applications:
Flow Cytometry

Conjugate:
Unconjugated

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
PECAM-1

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Antigen:
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Concentration:
__

Classification:
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Host Species:
Mouse

Target Species:
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Immunogen:
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Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
581

Applications:
Flow Cytometry

Conjugate:
APC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
gp105-120; My10; Hematopoietic progenitor cell antigen CD34

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Antigen:
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Concentration:
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Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
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Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
HIT2

Applications:
Flow Cytometry

Conjugate:
APC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
__