7092722
FoxP3 Mouse anti-Human, Alexa Fluor 647, Clone: 259D/C7, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
FoxP3
Applications
Flow Cytometry
Conjugate
Alexa Fluor 647
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype
IgG1
Purification Method
Affinity Purified
Description
Scurfin, IPEX, JM2
Clone
259D/C7
Classification
Monoclonal
Host Species
Mouse
Target Species
Baboon, Cynomolgus, Human, Rhesus Monkey
Immunogen
FoxP3 recombinant protein
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The 259D/C7 antibody reacts with the human FoxP3 transcription factor, a member of the forkhead or winged helix family of transcription factors
- The expression of FoxP3, also known as Scurfin, IPEX and JM2, has been found to be associated with CD4+ regulatory T cells and represents a specific marker for these cells
- Flow-cytometric analysis has shown that FoxP3 is expressed by the majority of CD4+CD25+high T cells in peripheral blood while less than half of CD4+CD25int cell population are FoxP3 positive
- Approximately 5-10% of peripheral CD4+ cells are CD4+CD25+ T regulatory cells
- T regulatory cells are thought to play a critical role in the control of T cell mediated autoimmunity by suppressing the proliferation and cytokine production of other T cells
- To support this hypothesis, it has been found that FOXP3 is mutated in scurfy (sf) mice
- The 259D/C7 antibody reacts with all currently identified isoforms of human FoxP3 and is cross-reactive with Cynomolgus, Rhesus and Baboon.
Compare Similar Items
Show Difference
Antigen: FoxP3
Applications: Flow Cytometry
Conjugate: Alexa Fluor 647
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Description: Scurfin, IPEX, JM2
Clone: 259D/C7
Classification: Monoclonal
Host Species: Mouse
Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
Immunogen: FoxP3 recombinant protein
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
FoxP3
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor 647
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Description:
Scurfin, IPEX, JM2
Clone:
259D/C7
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey
Immunogen:
FoxP3 recombinant protein
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: FoxP3
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Description: Scurfin, IPEX, JM2
Clone: 259D/C7
Classification: Monoclonal
Host Species: Mouse
Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
Immunogen: FoxP3 recombinant protein
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
FoxP3
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Description:
Scurfin, IPEX, JM2
Clone:
259D/C7
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey
Immunogen:
FoxP3 recombinant protein
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Granzyme B
Applications: Flow Cytometry
Conjugate: Alexa Fluor 647
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: GZMB; Granzyme-2; CCPI; CGL1; CSPB; CTLA1; CTSGL1; GRB; HLP; SECT
Clone: GB11
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Human Granzyme B
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Granzyme B
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor 647
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
GZMB; Granzyme-2; CCPI; CGL1; CSPB; CTLA1; CTSGL1; GRB; HLP; SECT
Clone:
GB11
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Human Granzyme B
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Granzyme B
Applications: Flow Cytometry
Conjugate: Alexa Fluor 647
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: GZMB; Granzyme-2; CCPI; CGL1; CSPB; CTLA1; CTSGL1; GRB; HLP; SECT
Clone: GB11
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Human Granzyme B
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Granzyme B
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor 647
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
GZMB; Granzyme-2; CCPI; CGL1; CSPB; CTLA1; CTSGL1; GRB; HLP; SECT
Clone:
GB11
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Human Granzyme B
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.