7092799
Stat4 (pY693) Mouse, PE, Clone: 38/P-STAT4, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Stat4 (pY693)
Applications
Flow Cytometry
Conjugate
PE
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype
IgG2b κ
Purification Method
Affinity Purified
Description
Signal transducer and activator of transcription 4; SLEB11
Clone
38/P-STAT4
Classification
Monoclonal
Host Species
Mouse
Target Species
Human, Mouse
Immunogen
Phosphorylated Human Stat4 (pY693)
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The Stat proteins function both as cytoplasmic signal transducers and as activators of transcription
- Seven mammalian Stat proteins have been identified: Stat1-4, Stat5a, 5b, and Stat6
- Stat4 has been shown to play an important role in development of T helper cells, specifically the Th1 subset
- Stat4 is activated by IL-12 and by type 1 interferons
- Knockout mice supported the role that Stat4 plays in IL-12 signaling because lymphocytes from Stat 4-/- mice could neither differentiate into Th1 cells nor produce IFN-γ in response to treatment with IL-12
- IFN-γ plays an important role in host defense
- A key component in the activation of Stat4 is the phosphorylation on tyrosine and serine residues in response to IL-12 stimulation
- IL-12 stimulation leads to the phosphorylation of Stat4 on tyrosine 693 and serine 721
- Transcriptional activity of Stat4 has been shown to be significantly reduced when residues Y693 and S721 are mutated.
Compare Similar Items
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Antigen: Stat4 (pY693)
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype: IgG2b κ
Purification Method: Affinity Purified
Description: Signal transducer and activator of transcription 4; SLEB11
Clone: 38/P-STAT4
Classification: Monoclonal
Host Species: Mouse
Target Species: Human, Mouse
Immunogen: Phosphorylated Human Stat4 (pY693)
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Stat4 (pY693)
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype:
IgG2b κ
Purification Method:
Affinity Purified
Description:
Signal transducer and activator of transcription 4; SLEB11
Clone:
38/P-STAT4
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human, Mouse
Immunogen:
Phosphorylated Human Stat4 (pY693)
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: __
Applications: __
Conjugate: __
Regulatory Status: __
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Isotype: __
Purification Method: __
Description: __
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Classification: __
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Immunogen: __
Primary or Secondary: __
Content And Storage: __
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Applications:
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Conjugate:
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Regulatory Status:
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Formulation:
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Isotype:
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Purification Method:
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Description:
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Clone:
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Classification:
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Host Species:
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Target Species:
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Immunogen:
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Primary or Secondary:
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Content And Storage:
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Antigen: Stat6 (pY641)
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG2a
Purification Method: Affinity Purified
Description: Signal transducer and activator of transcription 6; IL-4 Stat
Clone: 18/P-STAT6
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Phosphorylated Human Stat6 (pY641)
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Stat6 (pY641)
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG2a
Purification Method:
Affinity Purified
Description:
Signal transducer and activator of transcription 6; IL-4 Stat
Clone:
18/P-STAT6
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Phosphorylated Human Stat6 (pY641)
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: T- and B-Cell Activation Antigen
Applications: Flow Cytometry
Conjugate: FITC
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype: IgM κ
Purification Method: Affinity Purified
Description: GL7
Clone: GL7
Classification: Monoclonal
Host Species: Rat
Target Species: Mouse
Immunogen: In vitro-activated T-cell-depleted CBA/Ca mouse splenocytes
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
T- and B-Cell Activation Antigen
Applications:
Flow Cytometry
Conjugate:
FITC
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype:
IgM κ
Purification Method:
Affinity Purified
Description:
GL7
Clone:
GL7
Classification:
Monoclonal
Host Species:
Rat
Target Species:
Mouse
Immunogen:
In vitro-activated T-cell-depleted CBA/Ca mouse splenocytes
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.