Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Insulin
1.0 mg/mL
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Unconjugated
Mouse
Diabetes Research, Immune System Diseases, Immunology, Stem Cell Markers
PBS with No Preservative
3630
Recombinant INS protein
Primary
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
6 kDa
IRDN/794
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.1 - 0.2 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready
Monoclonal
Purified
RUO
Human, Mouse, Rat, Porcine, Primate
IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin
INS
IgG1 κ
Protein A or G purified
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.