Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Cytokeratin 7
1.0 mg/mL
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Unconjugated
Mouse
Cytoskeleton Markers
PBS with No Preservative
3855
OTN 11, ovarian carcinoma cell line
Primary
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
55 kDa
OV-TL12/30
Simple Western : 1.0 ug/ml, Flow Cytometry : 5 - 10 ul/million cells in 0.1ml, Immunohistochemistry-Paraffin : 1:100-1:200, Immunofluorescence : 1:50 - 1:100, CyTOF-ready
Monoclonal
Purified
RUO
Human
CK7, CK-7, cytokeratin 7, Cytokeratin-7, K2C7, K7keratin, 55K type II cytoskeletal, keratin 7, keratin, type II cytoskeletal 7, keratin-7, MGC129731, MGC3625, Sarcolectin, SCLkeratin, simple epithelial type I, K7, type II mesothelial keratin K7, Type-II keratin Kb7
KRT7
IgG1
Protein A or G purified
It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).