7106028
CD25/IL-2R alpha Antibody (Daclizumab) - Chimeric - Azide and BSA Free, Novus Biologicals™
Rabbit Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
CD25/IL-2 R alpha
Dilution
Flow Cytometry 1:10 - 1:1000, Blocking/Neutralizing 50 - 200 molar excess, CyTOF-ready
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Human
Gene Alias
CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Gene Symbols
IL2RA
Isotype
IgG
Purification Method
Protein A or G purified
Test Specificity
Binds to p55 chain of IL2R on human T cells, Tac antigen, which is expressed on T cells activated by mitogens, soluble antigens, and alloantigens but not on resting T cells, thymocytes, B cells, monocytes, activated B cells, leukemic T cell blasts from patients with acute lymphoblastic leukemia, and long-term T cell lines.
Clone
Daclizumab
Applications
Flow Cytometry, Blocking Assay, CyTOF
Conjugate
Unconjugated
Host Species
Rabbit
Research Discipline
Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Biologically Active Proteins, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
Formulation
PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez)
3559
Immunogen
Cultured T-cells derived from a patient with Mycosis fungoides.
Primary or Secondary
Primary
Content And Storage
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
Description
- CD25/IL-2R alpha Monoclonal specifically detects CD25/IL-2R alpha in Human, Cynomolgus Monkey, Rhesus Macaque samples
- It is validated for Flow Cytometry, CyTOF-ready, Block/Neutralize.
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Antigen: CD25/IL-2 R alpha
Dilution: Flow Cytometry 1:10 - 1:1000, Blocking/Neutralizing 50 - 200 molar excess, CyTOF-ready
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Gene Symbols: IL2RA
Isotype: IgG
Purification Method: Protein A or G purified
Test Specificity: Binds to p55 chain of IL2R on human T cells, Tac antigen, which is expressed on T cells activated by mitogens, soluble antigens, and alloantigens but not on resting T cells, thymocytes, B cells, monocytes, activated B cells, leukemic T cell blasts from patients with acute lymphoblastic leukemia, and long-term T cell lines.
Clone: Daclizumab
Applications: Flow Cytometry, Blocking Assay, CyTOF
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Biologically Active Proteins, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
Formulation: PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez): 3559
Immunogen: Cultured T-cells derived from a patient with Mycosis fungoides.
Primary or Secondary: Primary
Content And Storage: Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
Antigen:
CD25/IL-2 R alpha
Dilution:
Flow Cytometry 1:10 - 1:1000, Blocking/Neutralizing 50 - 200 molar excess, CyTOF-ready
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Gene Symbols:
IL2RA
Isotype:
IgG
Purification Method:
Protein A or G purified
Test Specificity:
Binds to p55 chain of IL2R on human T cells, Tac antigen, which is expressed on T cells activated by mitogens, soluble antigens, and alloantigens but not on resting T cells, thymocytes, B cells, monocytes, activated B cells, leukemic T cell blasts from patients with acute lymphoblastic leukemia, and long-term T cell lines.
Clone:
Daclizumab
Applications:
Flow Cytometry, Blocking Assay, CyTOF
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Biologically Active Proteins, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
Formulation:
PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez):
3559
Immunogen:
Cultured T-cells derived from a patient with Mycosis fungoides.
Primary or Secondary:
Primary
Content And Storage:
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
Antigen: CD25/IL-2 R alpha
Dilution: Western Blot 1:100 - 1:2000, Flow Cytometry 1:10 - 1:1000, Immunohistochemistry 1:10 - 1:500, Blocking/Neutralizing 50 - 200 molar excess, Immunofluorescence 1:10 - 1:500, CyTOF-ready
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Mouse, Rat
Gene Alias: CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Gene Symbols: IL2RA
Isotype: IgG
Purification Method: Protein A or G purified
Test Specificity: Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit - binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ( alpha beta yc) - T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.
Clone: Basiliximab
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Blocking Assay, Immunofluorescence, CyTOF
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
Formulation: PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez): 3559
Immunogen: CD25
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Antigen:
CD25/IL-2 R alpha
Dilution:
Western Blot 1:100 - 1:2000, Flow Cytometry 1:10 - 1:1000, Immunohistochemistry 1:10 - 1:500, Blocking/Neutralizing 50 - 200 molar excess, Immunofluorescence 1:10 - 1:500, CyTOF-ready
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat
Gene Alias:
CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Gene Symbols:
IL2RA
Isotype:
IgG
Purification Method:
Protein A or G purified
Test Specificity:
Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit - binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ( alpha beta yc) - T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.
Clone:
Basiliximab
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Blocking Assay, Immunofluorescence, CyTOF
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
Formulation:
PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez):
3559
Immunogen:
CD25
Primary or Secondary:
Primary
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Antigen: CD25/IL-2 R alpha
Dilution: Western Blot 1:100 - 1:2000, Flow Cytometry 1:10 - 1:1000, Immunohistochemistry 1:10 - 1:500, Blocking/Neutralizing 50 - 200 molar excess, Immunofluorescence 1:10 - 1:500, CyTOF-ready
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Mouse, Rat
Gene Alias: CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Gene Symbols: IL2RA
Isotype: IgG
Purification Method: Protein A or G purified
Test Specificity: Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit - binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ( alpha beta yc) - T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.
Clone: Basiliximab
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Blocking Assay, Immunofluorescence, CyTOF
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
Formulation: PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez): 3559
Immunogen: CD25
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Antigen:
CD25/IL-2 R alpha
Dilution:
Western Blot 1:100 - 1:2000, Flow Cytometry 1:10 - 1:1000, Immunohistochemistry 1:10 - 1:500, Blocking/Neutralizing 50 - 200 molar excess, Immunofluorescence 1:10 - 1:500, CyTOF-ready
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat
Gene Alias:
CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Gene Symbols:
IL2RA
Isotype:
IgG
Purification Method:
Protein A or G purified
Test Specificity:
Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit - binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ( alpha beta yc) - T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.
Clone:
Basiliximab
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Blocking Assay, Immunofluorescence, CyTOF
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
Formulation:
PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez):
3559
Immunogen:
CD25
Primary or Secondary:
Primary
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Antigen: CD19
Dilution: Flow Cytometry 1:10 - 1:1000, Immunohistochemistry 1:10 - 1:500, Immunoprecipitation 1:10 - 1:500, Blocking/Neutralizing 50 - 200 molar excess, Immunofluorescence 1:10 - 1:500, CyTOF-ready
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19 antigen, CD19 molecule, CVID3, Differentiation antigen CD19, MGC12802, T-cell surface antigen Leu-12
Gene Symbols: CD19
Isotype: IgG
Purification Method: Protein A or G purified
Test Specificity: Recognises human CD19.
Clone: HD37
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Blocking Assay, Immunofluorescence, CyTOF
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Adaptive Immunity, B Cell Development and Differentiation Markers, Cytokine Research, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Myeloid derived Suppressor Cell, Signal Transduction, Stem Cell Lines, Stem Cell Markers
Formulation: PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez): 930
Immunogen: Cells from a hairy cell leukemia patient.
Primary or Secondary: Primary
Content And Storage: Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
Antigen:
CD19
Dilution:
Flow Cytometry 1:10 - 1:1000, Immunohistochemistry 1:10 - 1:500, Immunoprecipitation 1:10 - 1:500, Blocking/Neutralizing 50 - 200 molar excess, Immunofluorescence 1:10 - 1:500, CyTOF-ready
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19 antigen, CD19 molecule, CVID3, Differentiation antigen CD19, MGC12802, T-cell surface antigen Leu-12
Gene Symbols:
CD19
Isotype:
IgG
Purification Method:
Protein A or G purified
Test Specificity:
Recognises human CD19.
Clone:
HD37
Applications:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Blocking Assay, Immunofluorescence, CyTOF
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cytokine Research, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Myeloid derived Suppressor Cell, Signal Transduction, Stem Cell Lines, Stem Cell Markers
Formulation:
PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene ID (Entrez):
930
Immunogen:
Cells from a hairy cell leukemia patient.
Primary or Secondary:
Primary
Content And Storage:
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.