7121492

Human/Mouse/Rat NEDD8 Antibody, R&D Systems™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

NEDD8

Dilution

Western Blot 2 ug/mL, Immunocytochemistry 8-25 ug/mL

Classification

Monoclonal

Host Species

Rat

Target Species

Human, Mouse, Rat

Gene Accession No.

Q15843

Gene ID (Entrez)

4738

Isotype

IgG2b

Purification Method

Protein A or G purified from hybridoma culture supernatant

Content And Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

Clone

866916

Applications

Western Blot, Immunocytochemistry

Conjugate

Unconjugated

Regulatory Status

RUO

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS.

Gene Alias

FLJ43224, MGC104393, MGC125896, MGC125897, NEDD-8, Neddylin, Neural precursor cell expressed developmentally down-regulated protein 8, neural precursor cell expressed, developmentally down-regulated 8, Rub1, Ubiquitin-like protein Nedd8

Immunogen

E. coli-derived recombinant human NEDD8 Leu2-Gly77 Accession # Q15843

Primary or Secondary

Primary

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Test Specificity

Detects human NEDD8 in direct ELISAs and Western blots.

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Description

  • NEDD8 Monoclonal specifically detects NEDD8 in Human, Mouse, Rat samples
  • It is validated for Western Blot, Immunocytochemistry.

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Fischer Scientific

7121492

Rat Monoclonal Antibody...


Antigen:
NEDD8

Dilution:
Western Blot 2 ug/mL, Immunocytochemistry 8-25 ug/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Human, Mouse, Rat

Gene Accession No.:
Q15843

Gene ID (Entrez):
4738

Isotype:
IgG2b

Purification Method:
Protein A or G purified from hybridoma culture supernatant

Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

Clone:
866916

Applications:
Western Blot, Immunocytochemistry

Conjugate:
Unconjugated

Regulatory Status:
RUO

Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS.

Gene Alias:
FLJ43224, MGC104393, MGC125896, MGC125897, NEDD-8, Neddylin, Neural precursor cell expressed developmentally down-regulated protein 8, neural precursor cell expressed, developmentally down-regulated 8, Rub1, Ubiquitin-like protein Nedd8

Immunogen:
E. coli-derived recombinant human NEDD8 Leu2-Gly77 Accession # Q15843

Primary or Secondary:
Primary

Reconstitution:
Reconstitute at 0.5 mg/mL in sterile PBS.

Test Specificity:
Detects human NEDD8 in direct ELISAs and Western blots.

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Fischer Scientific

7121494

Rat Monoclonal Antibody...


Antigen:
Meteorin-like/METRNL

Dilution:
Flow Cytometry 0.25 ug/10^6 cells, CyTOF-ready

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
Q8VE43

Gene ID (Entrez):
284207

Isotype:
IgG2b

Purification Method:
Protein A or G purified from hybridoma culture supernatant

Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

Clone:
829535

Applications:
Flow Cytometry, CyTOF

Conjugate:
Unconjugated

Regulatory Status:
RUO

Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS.

Gene Alias:
Meteorin like, meteorin, glial cell differentiation regulator-like, meteorin-like protein, METRNL, MGC99788

Immunogen:
Chinese hamster ovary cell line CHO-derived recombinant mouse METRNL Gln46-Glu311 Accession # Q8VE43

Primary or Secondary:
Primary

Reconstitution:
Reconstitute at 0.5 mg/mL in sterile PBS.

Test Specificity:
Detects mouse METRNL in direct ELISAs.

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7121496

Mouse Monoclonal Antibody...


Antigen:
MDGA2

Dilution:
Flow Cytometry 0.25 ug/10^6 cells

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human, Rat

Gene Accession No.:
Q72553

Gene ID (Entrez):
161357

Isotype:
IgG2b

Purification Method:
Protein A or G purified from hybridoma culture supernatant

Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

Clone:
803732

Applications:
Flow Cytometry

Conjugate:
Unconjugated

Regulatory Status:
RUO

Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS.

Gene Alias:
MAM domain containing glycosylphosphatidylinositol anchor 2, MAMDC1

Immunogen:
Mouse myeloma cell line NS0-derived recombinant human MDGA2 Gln21-Asp934 Accession # Q7Z553

Primary or Secondary:
Primary

Reconstitution:
Reconstitute at 0.5 mg/mL in sterile PBS.

Test Specificity:
Detects human MDGA2 in direct ELISAs. Detects rat MDGA2 in Flow Cytometry.

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7121499

Mouse Monoclonal Antibody...


Antigen:
MAML3

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
__

Gene ID (Entrez):
55534

Isotype:
IgG1

Purification Method:
Protein A or G purified

Content And Storage:
Store at -20 to -80C. Avoid freeze-thaw cycles.

Clone:
MAML3/1303

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF

Conjugate:
Unconjugated

Regulatory Status:
RUO

Formulation:
PBS with No Preservative

Gene Alias:
CAG/CTG 3, ERDA3, MAM-2, mam-3, mastermind-like 3 (Drosophila), mastermind-like protein 3, polyglutamine rich, trinucleotide repeat containing 3

Immunogen:
Recombinant human MAML3 protein fragment

Primary or Secondary:
Primary

Reconstitution:
__

Test Specificity:
MAML3 (mastermind-like protein 3) is a nuclear speckle protein that acts as a transcriptional coactivator for Notch receptors. The Notch signaling pathway influences cell fate by regulating the ability of precursor cells to properly respond to developmental signals. MAML3 is a member of the mastermind-like family of proteins that are human homologs of the Drosophila melanogaster mastermind protein. Through its N-terminal region, MAML3 interacts with the ankyrin repeats of the Notch proteins Notch 1, Notch 2, Notch 3 and Notch 4. This interaction leads to formation of a DNA-binding complex with the Notch proteins and RBP-Jk; a complex that can then induce HES1 gene expression. While the N-terminal domain of MAML3 is essential for proper Notch binding, the C-terminal domain of MAML3 is essential for transcriptional activation. Due to its involvement in cell signaling and transcriptional activation, upregulation of MAML3 is thought to be involved in oncogenesis.