CD11c Mouse anti-Human, Clone-ITGAX/1242, Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD11c
Concentration
1 mg/mL
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Human
Gene Alias
95, 95 alpha chain, 95, alpha subunit, CD11 antigen-like family member C, CD11c, CD11c antigen, CD11Cleu M5, alpha subunit, integrin alpha-X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit), Leu M5, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion receptor p150, leukocyte surface antigen p150, myeloid membrane antigen, alpha subunit, p150 95 integrin alpha chain, SLEB6
Gene Symbols
CD11c
Isotype
IgG κ
Purification Method
Protein A or G purified
Test Specificity
Recognizes a protein of 145kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.
Clone
ITGAX/1242
Dilution
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Dendritic Cell Markers, Signal Transduction
Formulation
PBS with No Preservative
Gene ID (Entrez)
3687
Immunogen
Recombinant fragment (191 Amino acid residues between aa 600-850) of human ITGAX protein
Primary or Secondary
Primary
Content And Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Molecular Weight of Antigen
145 kDa
Related Products
Description
- CD11c Monoclonal specifically detects CD11c in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.
Compare Similar Items
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Antigen: CD11c
Concentration: 1 mg/mL
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human
Gene Alias: 95, 95 alpha chain, 95, alpha subunit, CD11 antigen-like family member C, CD11c, CD11c antigen, CD11Cleu M5, alpha subunit, integrin alpha-X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit), Leu M5, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion receptor p150, leukocyte surface antigen p150, myeloid membrane antigen, alpha subunit, p150 95 integrin alpha chain, SLEB6
Gene Symbols: CD11c
Isotype: IgG κ
Purification Method: Protein A or G purified
Test Specificity: Recognizes a protein of 145kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.
Clone: ITGAX/1242
Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Dendritic Cell Markers, Signal Transduction
Formulation: PBS with No Preservative
Gene ID (Entrez): 3687
Immunogen: Recombinant fragment (191 Amino acid residues between aa 600-850) of human ITGAX protein
Primary or Secondary: Primary
Content And Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
Molecular Weight of Antigen: 145 kDa
Antigen: Cannabinoid R2/CB2/CNR2
Concentration: __
Applications: Flow Cytometry, CyTOF
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human
Gene Alias: cannabinoid receptor 2 (macrophage), CannabinoidR2, CB-2, CB2cannabinoid receptor 2, CB2R, CNR2, CX5, CX5testis-dominant CNR2 isoform CB2, hCB2
Gene Symbols: __
Isotype: IgG2b
Purification Method: Protein A or G purified from hybridoma culture supernatant
Test Specificity: Detects human Cannabinoid R2/CB2/CNR2 in direct ELISAs. Stains human Cannabinoid R2/CB2/CNR2 transfectants but not irrelevant transfectants in flow cytometry.
Clone: 352110
Dilution: Flow Cytometry 0.25 ug/10^6 cells, CyTOF-ready
Classification: Monoclonal
Host Species: Mouse
Research Discipline: __
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS.
Gene ID (Entrez): 1269
Immunogen: Human embryonic kidney cell line HEK293-derived transfected with human Cannabinoid R2/CB2/CNR2 Met1-Cys360 Accession # NP_001832
Primary or Secondary: Primary
Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Molecular Weight of Antigen: __
Antigen: Calnexin
Concentration: 1 mg/mL
Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human, Rat (Negative)
Gene Alias: calnexin, CNX, IP90FLJ26570, Major histocompatibility complex class I antigen-binding protein p88, P90
Gene Symbols: CANX
Isotype: IgG2b κ
Purification Method: Protein A or G purified
Test Specificity: __
Clone: CANX/1541
Dilution: Western Blot 0.5 - 1 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, CyTOF-ready
Classification: Monoclonal
Host Species: Mouse
Research Discipline: ER Markers, Neuroscience, Phospho Specific, Sensory Systems, Unfolded Protein Response, Vision
Formulation: PBS with No Preservative
Gene ID (Entrez): 821
Immunogen: Recombinant N-terminal fragment of human Calnexin protein (exact sequence is proprietary)
Primary or Secondary: Primary
Content And Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
Molecular Weight of Antigen: 90 kDa
