NB254431100

CD11c Mouse anti-Human, Clone-ITGAX/1242, Novus Biologicals™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 NB254431100-Each-of-1 In Stock ₹ 56,298.48

NB254431100 - Each of 1

₹ 56,298.48

In Stock

Quantity

1

Base Price: ₹ 56,298.48

GST (18%): ₹ 10,133.726

Total Price: ₹ 66,432.206

Antigen

CD11c

Classification

Monoclonal

Concentration

1 mg/mL

Dilution

Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready

Gene Alias

95, 95 alpha chain, 95, alpha subunit, CD11 antigen-like family member C, CD11c, CD11c antigen, CD11Cleu M5, alpha subunit, integrin alpha-X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit), Leu M5, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion receptor p150, leukocyte surface antigen p150, myeloid membrane antigen, alpha subunit, p150 95 integrin alpha chain, SLEB6

Host Species

Mouse

Molecular Weight of Antigen

145 kDa

Quantity

100 μg

Research Discipline

Dendritic Cell Markers, Signal Transduction

Gene ID (Entrez)

3687

Target Species

Human

Isotype

IgG κ

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF

Clone

ITGAX/1242

Conjugate

Unconjugated

Formulation

PBS with No Preservative

Gene Symbols

CD11c

Immunogen

Recombinant fragment (191 Amino acid residues between aa 600-850) of human ITGAX protein

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Recognizes a protein of 145kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.

Content And Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

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Description

  • CD11c Monoclonal specifically detects CD11c in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.

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Show Difference

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Fischer Scientific

NB254431100

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Antigen:
CD11c

Classification:
Monoclonal

Concentration:
1 mg/mL

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready

Gene Alias:
95, 95 alpha chain, 95, alpha subunit, CD11 antigen-like family member C, CD11c, CD11c antigen, CD11Cleu M5, alpha subunit, integrin alpha-X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit), Leu M5, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion receptor p150, leukocyte surface antigen p150, myeloid membrane antigen, alpha subunit, p150 95 integrin alpha chain, SLEB6

Host Species:
Mouse

Molecular Weight of Antigen:
145 kDa

Quantity:
100 μg

Research Discipline:
Dendritic Cell Markers, Signal Transduction

Gene ID (Entrez):
3687

Target Species:
Human

Isotype:
IgG κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF

Clone:
ITGAX/1242

Conjugate:
Unconjugated

Formulation:
PBS with No Preservative

Gene Symbols:
CD11c

Immunogen:
Recombinant fragment (191 Amino acid residues between aa 600-850) of human ITGAX protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 145kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.

Content And Storage:
Store at -20 to -80C. Avoid freeze-thaw cycles.

Img

Fischer Scientific

NB254431200

--


Antigen:
CD11c

Classification:
Monoclonal

Concentration:
1 mg/mL

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready

Gene Alias:
95, 95 alpha chain, 95, alpha subunit, CD11 antigen-like family member C, CD11c, CD11c antigen, CD11Cleu M5, alpha subunit, integrin alpha-X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit), Leu M5, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion receptor p150, leukocyte surface antigen p150, myeloid membrane antigen, alpha subunit, p150 95 integrin alpha chain, SLEB6

Host Species:
Mouse

Molecular Weight of Antigen:
145 kDa

Quantity:
200 μg

Research Discipline:
Dendritic Cell Markers, Signal Transduction

Gene ID (Entrez):
3687

Target Species:
Human

Isotype:
IgG κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF

Clone:
ITGAX/1242

Conjugate:
Unconjugated

Formulation:
PBS with No Preservative

Gene Symbols:
CD11c

Immunogen:
Recombinant fragment (191 Amino acid residues between aa 600-850) of human ITGAX protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 145kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.

Content And Storage:
Store at -20 to -80C. Avoid freeze-thaw cycles.

Img

Novus Biologicals

NB254433

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Antigen:
TCERG1

Classification:
Polyclonal

Concentration:
__

Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
CA150TATA box-binding protein-associated factor 2S, co-activator of 150 kDa, TAF2SMGC133200, TATA box binding protein (TBP)-associated factor, RNA polymerase II, S, 150kD, TATA box-binding protein-associated factor 2S, transcription elongation regulator 1, Transcription factor CA150, Urn1

Host Species:
Rabbit

Molecular Weight of Antigen:
__

Quantity:
0.1 mL

Research Discipline:
Cellular Markers, Transcription Factors and Regulators

Gene ID (Entrez):
10915

Target Species:
Human, Mouse

Isotype:
IgG

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
__

Conjugate:
Alexa Fluor 700

Formulation:
50mM Sodium Borate

Gene Symbols:
__

Immunogen:
A synthetic peptide made to a portion of human transcription elongation regulator 1 (CA150) encoded within exon 1 (LocusLink ID 10915).

Purification Method:
Immunogen affinity purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C in the dark.

Img

Fischer Scientific

NB254433100

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Antigen:
PTH

Classification:
Monoclonal

Concentration:
1 mg/mL

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready

Gene Alias:
Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1

Host Species:
Mouse

Molecular Weight of Antigen:
9 kDa

Quantity:
100 μg

Research Discipline:
Apoptosis, Biologically Active Proteins, Cancer

Gene ID (Entrez):
5741

Target Species:
Human

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF

Clone:
PTH/911

Conjugate:
Unconjugated

Formulation:
PBS with No Preservative

Gene Symbols:
PTH

Immunogen:
A synthetic peptide from the N-terminal of human PTH polypeptide.

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Epitope of this MAb maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

Content And Storage:
Store at -20 to -80C. Avoid freeze-thaw cycles.