7144237
USP5/IsoT Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
USP5/IsoT
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
Ubiquitin carboxyl-terminal hydrolase 5; Ubiquitin thiolesterase 5; Ubiquitin-specific processing protease 5; Deubiquitinating enzyme 5; Isopeptidase T
Gene Symbols
USP5
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunofluorescence, Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P45974
Gene ID (Entrez)
8078
Immunogen
Between 375 and 425
Primary or Secondary
Primary
Content And Storage
4° C
Gene
USP5
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon, Crab-eating macaque and Wh USP5 (ubiquitin carboxyl-terminal hydrolase 5) cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers
- It is involved in uchored Lys-48-linked polyubiquitin disassembly, and also binds linear and Lys-63 linked polyubiquitin with a lower affinity
- Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the uchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
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Antigen: USP5/IsoT
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: Ubiquitin carboxyl-terminal hydrolase 5; Ubiquitin thiolesterase 5; Ubiquitin-specific processing protease 5; Deubiquitinating enzyme 5; Isopeptidase T
Gene Symbols: USP5
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunofluorescence, Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P45974
Gene ID (Entrez): 8078
Immunogen: Between 375 and 425
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: USP5
Antigen:
USP5/IsoT
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
Ubiquitin carboxyl-terminal hydrolase 5; Ubiquitin thiolesterase 5; Ubiquitin-specific processing protease 5; Deubiquitinating enzyme 5; Isopeptidase T
Gene Symbols:
USP5
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunofluorescence, Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P45974
Gene ID (Entrez):
8078
Immunogen:
Between 375 and 425
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
USP5
Antigen: CENP-F/Mitosin
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: RP11-262H5.1, CENF, PRO1779, hcp-1
Gene Symbols: CENPF
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunofluorescence, Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P49454
Gene ID (Entrez): 1063
Immunogen: Between 2350 and 2400
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: CENPF
Antigen:
CENP-F/Mitosin
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
RP11-262H5.1, CENF, PRO1779, hcp-1
Gene Symbols:
CENPF
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunofluorescence, Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P49454
Gene ID (Entrez):
1063
Immunogen:
Between 2350 and 2400
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
CENPF
Antigen: SF3a120/SAP114
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: Splicing factor 3a, PRP21, PRPF21, SAP114, SF3A120
Gene Symbols: __
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunofluorescence, Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: Q15459, Q8K4Z5
Gene ID (Entrez): 10291, 67465
Immunogen: Between 300 and 350
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: SF3A1
Antigen:
SF3a120/SAP114
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
Splicing factor 3a, PRP21, PRPF21, SAP114, SF3A120
Gene Symbols:
__
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunofluorescence, Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
Q15459, Q8K4Z5
Gene ID (Entrez):
10291, 67465
Immunogen:
Between 300 and 350
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
SF3A1
Antigen: SF3b145/SAP145
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: Splicing factor 3B subunit 2, Pre-mRNA-splicing factor SF3b 145 kDa subunit, SF3b145, SF3b150, Spliceosome-associated protein 145, SAP 145, SF3B2, SAP145
Gene Symbols: __
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunofluorescence, Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: Q13435
Gene ID (Entrez): 10992, 319322
Immunogen: Between 775 and 825
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: SF3B2
Antigen:
SF3b145/SAP145
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
Splicing factor 3B subunit 2, Pre-mRNA-splicing factor SF3b 145 kDa subunit, SF3b145, SF3b150, Spliceosome-associated protein 145, SAP 145, SF3B2, SAP145
Gene Symbols:
__
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunofluorescence, Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
Q13435
Gene ID (Entrez):
10992, 319322
Immunogen:
Between 775 and 825
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
SF3B2