7145133

IgE Monoclonal Antibody (Ige21), Super Bright™ 600, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

IgE

Concentration

5 μL/Test

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias

HCAK1; IgA1; IgG3; IGHA1; IGHA2; IGHG1; IGHG2; IGHG3; IGHG4; IGKC; IGKCD; IGLC; IGLC1; Immunoglobulin E; immunoglobulin heavy constant alpha 1; immunoglobulin heavy constant alpha 2 (A2m marker); immunoglobulin heavy constant gamma 1 (G1m marker); immunoglobulin heavy constant gamma 2 (G2m marker); immunoglobulin heavy constant gamma 3 (G3m marker); immunoglobulin heavy constant gamma 4 (G4m marker); immunoglobulin kappa constant; immunoglobulin lambda constant 1; ImmunoglobulinE; Km

Gene Symbols

IGHE

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

IGHE

Clone

Ige21

Applications

Flow Cytometry

Conjugate

Super Bright 600

Host Species

Mouse

Target Species

Human

Gene Accession No.

P01854

Gene ID (Entrez)

3497

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Product Type

Antibody

Description

  • Description: The monoclonal antibody IgE21 recognizes the immunoglobulin E class of antibodies
  • The natural levels of IgE in the serum are quite low, comprising only a small portion of the total immunoglobulin
  • IgE plays a role in allergy responses by binding to mast cells and basophils through the Fc epsilon receptor I which results in the release of histamine and other molecules
  • The IgE is produced by terminally differentiated plasma B cells and basophils
  • Like all immunoglobulins, IgE is expressed as a soluble molecule as well as a membrane bound form
  • IgE21 recognizes both forms
  • Applications Reported: This IgE21 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This IgE21 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
  • This may be used at 5 μL (0.125 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Super Bright 600 is a tandem dye that can be excited with the violet laser line (405 nm) and emits at 600 nm
  • We recommend using a 610/20 bandpass filter
  • Please make sure that your instrument is capable of detecting this fluorochrome
  • When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Staining Buffer (Product No
  • IgE is one of the five classes of immunoglobulins found in mammals
  • Monomers consist of two heavy (epsilon) chains with 4 Ig-like constant domains, and two light chains
  • IgE plays an essential role in type I hypersensitivity (allergic responses such as hay fever, asthma, hives, anaphylatic shock) by binding to Fc receptors on basophils and mast cells
  • Crosslinking of IgE bound to Fc receptors induces degranulation of mast cells and basophils that promote allergic manifestations
  • IgE is also functionally important for immunity against parasites.

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Fischer Scientific

7145133

Mouse Monoclonal Antibody...


Antigen:
IgE

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
HCAK1; IgA1; IgG3; IGHA1; IGHA2; IGHG1; IGHG2; IGHG3; IGHG4; IGKC; IGKCD; IGLC; IGLC1; Immunoglobulin E; immunoglobulin heavy constant alpha 1; immunoglobulin heavy constant alpha 2 (A2m marker); immunoglobulin heavy constant gamma 1 (G1m marker); immunoglobulin heavy constant gamma 2 (G2m marker); immunoglobulin heavy constant gamma 3 (G3m marker); immunoglobulin heavy constant gamma 4 (G4m marker); immunoglobulin kappa constant; immunoglobulin lambda constant 1; ImmunoglobulinE; Km

Gene Symbols:
IGHE

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
IGHE

Clone:
Ige21

Applications:
Flow Cytometry

Conjugate:
Super Bright 600

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P01854

Gene ID (Entrez):
3497

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
T-bet

Concentration:
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Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21

Gene Symbols:
Tbx21

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Tbx21

Clone:
eBio4B10 (4B10)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Mouse

Target Species:
Human, Mouse, Rhesus Monkey

Gene Accession No.:
Q9JKD8, Q9UL17

Gene ID (Entrez):
30009, 57765, 694044

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
TCR gamma/delta

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
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Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
RGD1311300; similar to T cell receptor V delta 6; T cell receptor gamma locus; T3/TCR complex; TCR delta gamma; TCR gamma/delta; TCR-CD3 complex; Tcrg; Trg; Trg@

Gene Symbols:
Tcrd, Tcrg

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
__

Clone:
eBioGL3 (GL-3, GL3), GL3)

Applications:
Flow Cytometry

Conjugate:
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Host Species:
Armenian Hamster

Target Species:
Mouse

Gene Accession No.:
0

Gene ID (Entrez):
110066, 110067

Isotype:
IgG

Purification Method:
Affinity chromatography

Product Type:
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Antigen:
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Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
4632428N05Rik; B7H5; B7-H5; C10orf54; C1H10orf54; C28H10orf54; C4H10orf54; chromosome 10 open reading frame 54; DD1alpha; Death Domain1alpha; Dies1; differentiation of ESCs 1; GI24; PD-1H; PDCD1 homolog; PD-H1; platelet receptor Gi24; PP2135; RIKEN cDNA 4632428N05 gene; SISP1; sisp-1; Stress-induced secreted protein-1; UNQ730/PRO1412; V-domain Ig suppressor of T cell activation; VISTA; V-set domain-containing immunoregulatory receptor; V-set immunoregulatory receptor; VSIR; V-type immunoglobulin domain-containing suppressor of T-cell activation

Gene Symbols:
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Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
VSIR

Clone:
B7H5DS8

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q9H7M9

Gene ID (Entrez):
64115

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody