7159121
SIGLEC H Monoclonal Antibody (eBio440c), Super Bright™ 600, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
SIGLEC H
Concentration
0.2 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias
6430529G09Rik; sialic acid binding Ig-like lectin H; Siglec; Siglech; Siglec-H; SIGLEC-like protein
Gene Symbols
Siglech
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Gene
Siglech
Clone
eBio440c
Applications
Flow Cytometry
Conjugate
Super Bright 600
Host Species
Rat
Target Species
Mouse
Gene Accession No.
0
Gene ID (Entrez)
233274
Isotype
IgG2b κ
Purification Method
Affinity chromatography
Product Type
Antibody
Related Products
Description
- The monoclonal antibody eBio440c recognizes Siglec-H, a protein exclusively found on pDC (plasmacytoid dendritic cells) or type I IFN-producing cells (IPC) in the naive mouse
- Mouse IPC are typically PDCA+, CD11c+, CD11b-, B220+, and Ly-6C+ Siglec-H, a protein exclusively found on pDC (plasmacytoid dendritic cells) or type I IFN-producing cells (IPC) in the naive mouse
- Mouse IPC are typically PDCA+, CD11c+, CD11b-, B220+, and Ly-6C+, and are quick to respond to viruses
- Siglec-H is a transmembrane protein of the Ig superfamily that like CD33 have been shown to bind sialic acid but lacks the characteristic cytoplasmic ITIM domain (immunoreceptor tyrosine based inhibitory motif)
- To overcome the lack of a cytoplasmic domain, Siglec-H associates with DAP12 thereby allowing for signal transduction
- The eBio440c antibody has been shown to inhibit pDC function (inhbits IFNalpha secretion in response to CpG)
- It has been observed that some mouse strains (such as SJL) have higher percentages of pDCs compared to C57BL/6.
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Antigen: SIGLEC H
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias: 6430529G09Rik; sialic acid binding Ig-like lectin H; Siglec; Siglech; Siglec-H; SIGLEC-like protein
Gene Symbols: Siglech
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: Siglech
Clone: eBio440c
Applications: Flow Cytometry
Conjugate: Super Bright 600
Host Species: Rat
Target Species: Mouse
Gene Accession No.: 0
Gene ID (Entrez): 233274
Isotype: IgG2b κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
SIGLEC H
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
6430529G09Rik; sialic acid binding Ig-like lectin H; Siglec; Siglech; Siglec-H; SIGLEC-like protein
Gene Symbols:
Siglech
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
Siglech
Clone:
eBio440c
Applications:
Flow Cytometry
Conjugate:
Super Bright 600
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
0
Gene ID (Entrez):
233274
Isotype:
IgG2b κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: T-bet
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Gene Symbols: Tbx21
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: Tbx21
Clone: eBio4B10 (4B10)
Applications: Flow Cytometry
Conjugate: eFluor 450
Host Species: Mouse
Target Species: Human, Mouse, Rhesus Monkey
Gene Accession No.: Q9JKD8, Q9UL17
Gene ID (Entrez): 30009, 57765, 694044
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
T-bet
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Gene Symbols:
Tbx21
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
Tbx21
Clone:
eBio4B10 (4B10)
Applications:
Flow Cytometry
Conjugate:
eFluor 450
Host Species:
Mouse
Target Species:
Human, Mouse, Rhesus Monkey
Gene Accession No.:
Q9JKD8, Q9UL17
Gene ID (Entrez):
30009, 57765, 694044
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: VSIG4
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias: A530061A11; BC025105; complement receptor of the immunoglobulin superfamily; CRIg; Ig superfamily protein; MGC137243 protein; protein Z39Ig; UNQ317/PRO362; V-set and immunoglobulin domain containing 4; V-set and immunoglobulin domain-containing protein 4; VSIG4; Z39IG
Gene Symbols: VSIG4
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: VSIG4
Clone: JAV4
Applications: Flow Cytometry
Conjugate: Super Bright 436
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q9Y279
Gene ID (Entrez): 11326
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
VSIG4
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
A530061A11; BC025105; complement receptor of the immunoglobulin superfamily; CRIg; Ig superfamily protein; MGC137243 protein; protein Z39Ig; UNQ317/PRO362; V-set and immunoglobulin domain containing 4; V-set and immunoglobulin domain-containing protein 4; VSIG4; Z39IG
Gene Symbols:
VSIG4
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
VSIG4
Clone:
JAV4
Applications:
Flow Cytometry
Conjugate:
Super Bright 436
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q9Y279
Gene ID (Entrez):
11326
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
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Antibody
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