7162580

BRCC3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

BRCC3

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Gene Accession No.

P46736

Gene ID (Entrez)

79184

Isotype

IgG

Content And Storage

-20°C or -80°C if preferred

Gene

BRCC3

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Alias

6.1A protein, BRCA1/BRCA2-containing complex subunit 3, BRCA1/BRCA2-containing complex subunit 36, BRCA1/BRCA2-containing complex, subunit 3, BRCA1-A complex subunit BRCC36, Brcc3, BRCC36, BRISC complex subunit BRCC36, C6.1A, CXorf53, lys-63-specific deubiquitinase BRCC36, RP11-143H17.2

Gene Symbols

BRCC3

Primary or Secondary

Primary

Product Type

Antibody

Description

  • Together with the breast and ovarian predisposition proteins BRCA1 and BRCA2 and RAD51 and BRCC45, BRCC36 forms a holoenzyme complex that possesses a ubiquitin E3 ligase activity
  • Aberrant levels of BRCC36 were detected in sporadic breast tumors and depletion of either BRCC36 or BRCC45 by siRNA resulted in increased sensitivity to ionizing radiation and defects in the G2/M checkpoint, indicating that BRCC36 acts to enhance cellular survival following DNA damage
  • Recent experiments have shown that BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation, suggesting that BRCC36 may be an important target in the treatment of radiation-resistant breast tumors
  • At least two isoforms of BRCC36 are known to exist.

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7162580

Rabbit Polyclonal Antibody...


Antigen:
BRCC3

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Gene Accession No.:
P46736

Gene ID (Entrez):
79184

Isotype:
IgG

Content And Storage:
-20°C or -80°C if preferred

Gene:
BRCC3

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Alias:
6.1A protein, BRCA1/BRCA2-containing complex subunit 3, BRCA1/BRCA2-containing complex subunit 36, BRCA1/BRCA2-containing complex, subunit 3, BRCA1-A complex subunit BRCC36, Brcc3, BRCC36, BRISC complex subunit BRCC36, C6.1A, CXorf53, lys-63-specific deubiquitinase BRCC36, RP11-143H17.2

Gene Symbols:
BRCC3

Primary or Secondary:
Primary

Product Type:
Antibody

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7162581

Rabbit Polyclonal Antibody...


Antigen:
Carbonic Anhydrase I

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Gene Accession No.:
P00915, P13634

Gene ID (Entrez):
12346, 759

Isotype:
IgG

Content And Storage:
-20°C or -80°C if preferred

Gene:
CA1

Applications:
__

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Alias:
AW555628, CA I, CA1, ca1 {ECO:0000250, CAB, CA-I, CA-I {ECO:0000250, Car1, Car-1, Carbonate dehydratase I, carbonate dehydratase I {ECO:0000250, carbonic anhydrase 1, carbonic anhydrase 1 {ECO:0000250, Carbonic anhydrase B, carbonic anhydrase I, carbonic anhydrase I {ECO:0000250, epididymis secretory protein Li 11, HEL-S-11, UniProtKB:P00915}

Gene Symbols:
CA1, Car1

Primary or Secondary:
Primary

Product Type:
Antibody

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7162586

Mouse Monoclonal Antibody...


Antigen:
CD163

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Gene Accession No.:
Q86VB7

Gene ID (Entrez):
9332

Isotype:
IgG1 κ

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CD163

Applications:
Flow Cytometry

Conjugate:
Alexa Fluor 488

Host Species:
Mouse

Target Species:
Human

Gene Alias:
CD163, CD163 antigen, CD163 molecule, CD163v2, CD163v3, Hemoglobin scavenger receptor, M130, macrophage-associated antigen, MM130, putative CD163 antigen, SCARI1, Scavenger receptor cysteine-rich type 1 protein M130, sCD163, Soluble CD163, Soluble sCD163

Gene Symbols:
CD163

Primary or Secondary:
Primary

Product Type:
Antibody

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7162592

Mouse Monoclonal Antibody...


Antigen:
CD25

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Gene Accession No.:
P01589

Gene ID (Entrez):
3559

Isotype:
IgG1 κ

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
IL2RA

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Mouse

Target Species:
Human

Gene Alias:
ADA, ADA1, Adenosine aminohydrolase, adenosine deaminase, CD25, CD25 antigen, cytokine receptor, IDDM10, IL 2 RA, IL 2 receptor, IL 2R, IL 2R subunit alpha, IL2 RA, IL2 RA antibody, IL2 receptor, il-2 receptor alpha, IL-2 Receptor alpha chain, IL-2 receptor alpha subunit, IL2 receptor subunit alpha, IL-2 receptor subunit alpha, IL2R, IL-2R alpha, IL-2R alpha chain, IL2R subunit alpha, IL-2R subunit alpha, Il2ra, IL-2RA, IL-2-RA, IL2-RA, Il2ra antibody, IL2RAC, IMD41, interleukin 2 receptor, interleukin 2 receptor alpha chain, interleukin 2 receptor subunit alpha, interleukin 2 receptor, alpha, interleukin 2 receptor, alpha chain, interleukin-2 receptor alpha, interleukin-2 receptor alpha chain, interleukin-2 receptor alpha subunit, interleukin-2 receptor beta chain, Interleukin2 receptor subunit alpha, interleukin-2 receptor subunit alpha, Ly-43, p55, p55 chain, sIL 2R, soluble IL 2 receptor, TAC antigen, TCGFR

Gene Symbols:
IL2RA

Primary or Secondary:
Primary

Product Type:
Antibody