7182617

Emerin, Mouse anti-Human, Clone: EMD/2167, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Emerin

Concentration

0.2 mg/mL

Applications

Western Blot, Immunohistochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P50402

Gene ID (Entrez)

2010

Immunogen

Recombinant human Emerin protein fragment (around aa 56-167) (exact sequence is proprietary)

Primary or Secondary

Primary

Content And Storage

Store at 4°C.

Clone

EMD/2167

Dilution

Western Blot 1-2 ug/ml, Immunohistochemistry 1-2 ug/ml, Immunocytochemistry/Immunofluorescence 1-3 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Formulation

10 mM PBS with 0.05% BSA

Gene Alias

emerin, Emery-Dreifuss muscular dystrophy, LEM domain containing 5, STAEDMDLEMD5

Gene Symbols

EMD

Isotype

IgG1 κ

Purification Method

Protein A or G purified

Test Specificity

Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized by slowly progressing contractures, skeletal muscle wasting and cardiomyopathy. Reportedly, lack of Emerin expression is one cause of EDMD. Emerin is involved in the association of the nuclear membrane with the lamina, and is localized specifically to desmosomes and fasciae adherents in the heart. Identification of nuclear membrane irregularities with anti-emerin antibody has been reported useful in diagnosing papillary thyroid carcinoma.

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Description

  • Emerin Monoclonal specifically detects Emerin in Human samples
  • It is validated for Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Protein Array.

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Show Difference

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7182617

Mouse Monoclonal Antibody...


Antigen:
Emerin

Concentration:
0.2 mg/mL

Applications:
Western Blot, Immunohistochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P50402

Gene ID (Entrez):
2010

Immunogen:
Recombinant human Emerin protein fragment (around aa 56-167) (exact sequence is proprietary)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C.

Clone:
EMD/2167

Dilution:
Western Blot 1-2 ug/ml, Immunohistochemistry 1-2 ug/ml, Immunocytochemistry/Immunofluorescence 1-3 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Formulation:
10 mM PBS with 0.05% BSA

Gene Alias:
emerin, Emery-Dreifuss muscular dystrophy, LEM domain containing 5, STAEDMDLEMD5

Gene Symbols:
EMD

Isotype:
IgG1 κ

Purification Method:
Protein A or G purified

Test Specificity:
Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized by slowly progressing contractures, skeletal muscle wasting and cardiomyopathy. Reportedly, lack of Emerin expression is one cause of EDMD. Emerin is involved in the association of the nuclear membrane with the lamina, and is localized specifically to desmosomes and fasciae adherents in the heart. Identification of nuclear membrane irregularities with anti-emerin antibody has been reported useful in diagnosing papillary thyroid carcinoma.

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7182620

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Antigen:
C1QB

Concentration:
0.2 mg/mL

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P02746

Gene ID (Entrez):
713

Immunogen:
Recombinant fragment (around aa 41-188) of human C1QB protein (exact sequence is proprietary)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C.

Clone:
C1QB/2965

Dilution:
Immunohistochemistry 1-2 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Formulation:
10 mM PBS with 0.05% BSA

Gene Alias:
B chain, complement C1q subcomponent subunit B, complement component 1, q subcomponent, B chain, complement subcomponent C1q chain B, q subcomponent, beta polypeptide

Gene Symbols:
C1QB

Isotype:
IgG1 κ

Purification Method:
Protein A or G purified

Test Specificity:
__

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Antigen:
TRAF-1

Concentration:
0.2 mg/mL

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q13077, Q13077

Gene ID (Entrez):
7185

Immunogen:
Recombinant fragment of human TRAF-1 protein (around aa 73-219) (exact sequence is proprietary)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C.

Clone:
TRAF1/2770

Dilution:
Immunohistochemistry 1-2 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Formulation:
10 mM PBS with 0.05% BSA

Gene Alias:
EBI6MGC:10353, Epstein-Bar virus-induced protein 6, Epstein-Barr virus-induced protein 6, TNF receptor-associated factor 1

Gene Symbols:
TRAF1

Isotype:
IgG1 κ

Purification Method:
Protein A or G purified

Test Specificity:
This monoclonal antibody recognizes a protein of 52kDa, which is identified as TRAF-1 (TNFR-associated factor 1), which is highly useful for the differentiation of LyP and cALCL in patients with cutaneous CD30-positive lymphoproliferations. CD30-positive lymphoproliferations of the skin comprise 30% of all primary cutaneous T-cell lymphomas (CTCLs). Besides borderline cases this group includes lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large T-cell lymphoma (cALCL).

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Antigen:
TRAF-1

Concentration:
0.2 mg/mL

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q13077, Q13077

Gene ID (Entrez):
7185

Immunogen:
Recombinant fragment of human TRAF-1 protein (around aa 73-219) (exact sequence is proprietary)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C.

Clone:
TRAF1/3298

Dilution:
Immunohistochemistry 1-2 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Formulation:
10 mM PBS with 0.05% BSA

Gene Alias:
EBI6MGC:10353, Epstein-Bar virus-induced protein 6, Epstein-Barr virus-induced protein 6, TNF receptor-associated factor 1

Gene Symbols:
TRAF1

Isotype:
IgG2b κ

Purification Method:
Protein A or G purified

Test Specificity:
This monoclonal antibody recognizes a protein of 52kDa, which is identified as TRAF-1 (TNFR-associated factor 1), which is highly useful for the differentiation of LyP and cALCL in patients with cutaneous CD30-positive lymphoproliferations. CD30-positive lymphoproliferations of the skin comprise 30% of all primary cutaneous T-cell lymphomas (CTCLs). Besides borderline cases this group includes lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large T-cell lymphoma (cALCL).