NPM1, Mouse anti-Human, Clone: NPM1/1902, Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
NPM1
Concentration
0.2 mg/mL
Applications
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array
Conjugate
Unconjugated
Host Species
Mouse
Research Discipline
Apoptosis, Cancer, Cell Cycle and Replication, Chromatin Research, DNA replication Transcription Translation and Splicing, Mitotic Regulators, Phospho Specific, Signal Transduction, Tumor Suppressors
Formulation
10 mM PBS with 0.05% BSA
Gene Alias
B23, MGC104254, NPMnucleophosmin/nucleoplasmin family, member 1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), numatrin
Gene Symbols
NPM1
Isotype
IgG2b κ
Purification Method
Protein A or G purified
Test Specificity
This antibody recognizes a 33kDa glycoprotein, identified as Nucleophosmin (NPM1). It is predominantly localized in the nucleus of cells in most tissues. NPM1 is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia.
Clone
NPM1/1902
Dilution
Western Blot 1-2 ug/ml, ELISA 2-4 ug/ml, Immunohistochemistry 1-2 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Human
Gene Accession No.
P06748, P06748
Gene ID (Entrez)
4869
Immunogen
Recombinant human NPM1 protein fragment (aa185-287) (exact sequence is proprietary)
Primary or Secondary
Primary
Content And Storage
Store at 4°C.
Related Products
Description
- NPM1 Monoclonal specifically detects NPM1 in Human samples
- It is validated for Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Protein Array.
Compare Similar Items
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Antigen: NPM1
Concentration: 0.2 mg/mL
Applications: Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Apoptosis, Cancer, Cell Cycle and Replication, Chromatin Research, DNA replication Transcription Translation and Splicing, Mitotic Regulators, Phospho Specific, Signal Transduction, Tumor Suppressors
Formulation: 10 mM PBS with 0.05% BSA
Gene Alias: B23, MGC104254, NPMnucleophosmin/nucleoplasmin family, member 1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), numatrin
Gene Symbols: NPM1
Isotype: IgG2b κ
Purification Method: Protein A or G purified
Test Specificity: This antibody recognizes a 33kDa glycoprotein, identified as Nucleophosmin (NPM1). It is predominantly localized in the nucleus of cells in most tissues. NPM1 is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia.
Clone: NPM1/1902
Dilution: Western Blot 1-2 ug/ml, ELISA 2-4 ug/ml, Immunohistochemistry 1-2 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Accession No.: P06748, P06748
Gene ID (Entrez): 4869
Immunogen: Recombinant human NPM1 protein fragment (aa185-287) (exact sequence is proprietary)
Primary or Secondary: Primary
Content And Storage: Store at 4°C.
Antigen: Pax2
Concentration: 0.2 mg/mL
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Chaperone Mediated Autophagy (CMA), Neuronal Cell Markers, Stem Cell Markers
Formulation: 10 mM PBS with 0.05% BSA
Gene Alias: paired box 2, paired box gene 2, paired box homeotic gene 2, paired box protein Pax-2
Gene Symbols: PAX2
Isotype: IgG2b κ
Purification Method: Protein A or G purified
Test Specificity: This antibody recognizes a protein of 42kDa, which is identified as Pax2. Pax2 has been used as a marker for the identification of renal cell carcinoma and ovarian carcinoma by immunohistochemistry.
Clone: PAX2/1104
Dilution: ELISA, Immunohistochemistry 1-2 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Accession No.: Q02962, Q02962
Gene ID (Entrez): 5076
Immunogen: Recombinant fragment (around aa 223-354) human Pax2 protein (exact sequence is proprietary)
Primary or Secondary: Primary
Content And Storage: Store at 4°C.
Antigen: Pax2
Concentration: 0.2 mg/mL
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Chaperone Mediated Autophagy (CMA), Neuronal Cell Markers, Stem Cell Markers
Formulation: 10 mM PBS with 0.05% BSA
Gene Alias: paired box 2, paired box gene 2, paired box homeotic gene 2, paired box protein Pax-2
Gene Symbols: PAX2
Isotype: IgG2b κ
Purification Method: Protein A or G purified
Test Specificity: This antibody recognizes a protein of 42kDa, which is identified as Pax2. Pax2 has been used as a marker for the identification of renal cell carcinoma and ovarian carcinoma by immunohistochemistry.
Clone: PAX2/1104
Dilution: ELISA, Immunohistochemistry 1-2 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Accession No.: Q02962, Q02962
Gene ID (Entrez): 5076
Immunogen: Recombinant fragment (around aa 223-354) human Pax2 protein (exact sequence is proprietary)
Primary or Secondary: Primary
Content And Storage: Store at 4°C.
